Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

• Status: Not yet recruiting
• Trial end date: 2024-02-01
• Target enrollment: 0
• Participant gender: All

Summary

One initial study has shown that Botulinum Toxin (BT) in combination with zinc supplementation may increase the duration of effects BT treatment. This initial study was in the context of facial aesthetics. The purpose of the present study is to determine the effect, if any, of oral zinc supplementation prior to BT in the treatment of spasmodic dysphonia. If positive effects will be observed, this would help reduce the burden of disease for these patients.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Florida
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; Zinc

Criteria

Inclusion Criteria:

• Adults patients

• 18 years old and above

• Current diagnosis of ADductor spasmodic dysphonia

• Has had Botox injection treatments for SD > 6 months

Exclusion Criteria:

• Pregnant

• Diagnosis of ABductor spasmodic dysphonia

• Patients taking > 30 mg zinc supplementation daily prior to study beginning