a Small Dose of Naloxone,Minimize Intrathecal Morphine Side Effects

• Status: Completed
• Trial end date: 2017-04-01
• Target enrollment: 0
• Participant gender: All

Summary

I.V naloxone decreases incidence and severity of the common morphine side effects (pruritis, nausea/emesis, constipation, urinary retention, respiratory depression and undesirable sedation) so using it as additive to intrathecal morphine in patients undergoing anal surgeries under spinal anesthesia may be beneficail

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Bupivacaine; Morphine; Naloxone

Criteria

Inclusion Criteria:

• ASA physical status I - II

• undergoing anal surgery with spinal anesthesia

Exclusion Criteria:

• Renal ,hepatic and cardiac patients -Infection at the site of injection.-

• Coagulopathy or other bleeding diathesis. -Preexisting neurologic deficits.-

• History of hypersensitivity to any of the given the drugs.

• Inability to communicate with the investigator and the hospital staff.

• History of chronic opioid use.