Overview

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Status:
Not yet recruiting

Trial end date:
2026-09-01

Target enrollment:

Participant gender:

Summary

The purpose of this clinical trial is to investigate if prolonged antibiotics after pancreatoduodenectomy can prevent the development of a pancreatic fistula and related complications. Participants who are at high risk of pancreatic fistula will be administered an extended course of antibiotics. While inpatient, the patient will receive these antibiotics through the vein, and after discharge, the antibiotics will be taken by mouth.

Phase:

Phase 2

Details

Lead Sponsor:

Case Comprehensive Cancer Center

Treatments:

Amoxicillin
Clavulanic Acid
Clavulanic Acids
Piperacillin
Piperacillin, Tazobactam Drug Combination
Tazobactam