fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults
Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study was to characterize how the anti-cholinesterase inhibitor (AChE-I)
donepezil modulates brain regions involved in visual short-term memory, episodic memory and
inhibitory efficiency following 24 hours of total sleep deprivation using fMRI as an
additional marker for drug effect.