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Clinical Trials for Bone Marrow Diseases

• A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
• Efficacy and Safety of Apalutamide in Combination With 89Sr as Neoadjuvant Therapy in Prostate Cancer With ≤10 Bone Metastases
• TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer
• Diagnostic Performance and Safety of 18F-NaF-PET/CT in Bone Metastases Compared With 99mTc⁃MDP-BS±SPECT
• Efficacy of Sr-89 for Differentiated Thyroid Cancer With Bone Metastases
• Efficacy and Safety of LY01011 and Xgeva® in Patients With Bone Metastases From Solid Tumors
• Efficacy and Safety of MW032 and Xgeva® in Subjects With Bone Metastases From Solid Tumors
• Regeneration in Cervical Degenerative Myelopathy
• Efficacy and Safety of JMT103 in Patients With Bone Metastases From Solid Tumors
• To Evaluate the Efficacy and Safety of QL1206 and Xgeva in Patients With Bone Metastases From Solid Tumors
• Denosumab in Combination With Enzalutamide in Progressive Metastatic Castrate-resistant Prostate Cancer and Bone Metastases.
• Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study
• Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasis
• Denosumab and Nivolumab Combination as 2d-line Therapy in Stage IV NSC Lung Cancer With Bone Metastases (DENIVOS)
• Pilot, Syndros, Decreasing Use of Opioids in Breast Cancer Subjects With Bone Mets
• Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer
• Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone Metastasis
• Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to Bone
• Merestinib on Bone Metastases in Subjects With Breast Cancer
• A Study of KW-0761 in Subjects With HTLV-1 Associated Myelopathy (HAM)
• Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDS
• Dose-finding, Safety and Efficacy Study of Radium-223 Dichloride (XOFIGO) in RCC Patients With Bone Metastases. (EIFFEL)
• Investigating the Safety, Tolerability and Efficacy of Amorphous Calcium Carbonate (ACC) on the Treatment of Subjects With CRPC
• Evaluation of Medical Practice in the Management of Bone Metastases After Injectable Bone Antiresorptive Treatment, and Its Influence on Quality of Life
• Preliminary Evaluation of Uptake in Bone Metastases and Biodistribution of [68Ga]P15-041
• Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors
• Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy
• Androgen Deprivation Therapy +/- Radium-223 Dichloride in Metastatic Prostate Cancer With Bone Metastases
• Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer
• Pain Management With Pecfent in the Prevention of Pain Induced by Position in Radiotherapy
• Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
• Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors
• A Phase 2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Myelofibrosis
• The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
• Single Shot Intrathecal Ziconotide for Painful Neuropathy or Myelopathy
• Bone Marrow Transplant With Abatacept for Non-Malignant Diseases
• Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.
• A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
• A Phase II Clinical Trial on Comparison of Effectiveness and Safeness of Different Amifostine Regimens
• Dexamethasone for Pain Flare After Radiotherapy of Painful Bone metastasesZonMW 11510009
• MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases
• Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia
• Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer
• A Double-Blind, Placebo Controlled Study of Intravenous Immunoglobulin for HIV-Associated Myelopathy
• Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
• Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients
• Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to Bone
• Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer
• Hydroxychloroquine in Treating Patients With Solid Tumors Undergoing Radiation Therapy for Bone Metastases
• Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
• Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
• Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect)
• Dexamethasone vs Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone Metastases
• Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients
• A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)
• Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only
• Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
• Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
• Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
• Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates
• Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis
• A Phase I/II Open-label Study of MCS110 in Patients With Prostate Cancer and Bone Metastases
• BAY88-8223, Does Response Study in HRPC Patients
• Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis
• Docetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone Therapy
• Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis
• Phase IIa Vorinostat (MK0683, Suberoylanilide Hydroxamic Acid (SAHA)) Study in Lower Risk Myelodysplastic Syndromes (0683-064)
• Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer
• Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.
• Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer
• A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.
• Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial
• Safety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases Palliation
• Assessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone Metastasis
• Effect of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastasis
• Efficacy and Safety of Zoledronic Acid in Patients With Bone Metastases of Any Solid Tumors or Multiple Myeloma
• Concurrent Xeloda and Radiotherapy for Bone Metastases
• Study of Fentanyl-Propofol-EMLA of L.M.X4 Technique for Bone Marrow Aspiration
• Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone
• Stem Cell Transplant for Bone Marrow Failure Syndromes
• Stem Cell Transplant for Hemoglobinopathy
• SCIO-469: Open-Label Study for Patients With Myelodysplastic Syndromes.
• Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates
• Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer
• Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
• Treatment of AIDS Vacuolar Myelopathy With Methionine
• 12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder
• Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM)