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Clinical Trials for Myotonic Disorders

• An Open-Label Extension Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (FREEDOM-OLE)
• Global Open-Label Extension Study of Del-desiran for the Treatment of DM1
• A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I
• Global Study of Del-desiran for the Treatment of DM1
• Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1
• Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients
• Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients
• Open Label Study in Adolescents and Children With Myotonic Disorders
• Open-label Extension Study in Paediatric Patients Who Have Completed the MEX-NM-301 Study.
• Mexiletine and Non Dystrophic Myotonias
• Study of Ranolazine in Myotonia Congenita, Paramyotonia Congenita and Myotonic Dystrophy Type 1
• Lamotrigine as Treatment of Myotonia
• Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders