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Clinical Trials for Porphyrias

• Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Variegate Porphyria (VP)
• A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP)
• ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)
• Harvoni Treatment Porphyria Cutanea Tarda
• A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)
• Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
• Acute Porphyria Biomarkers for Disease Activity
• A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
• Hydroxychloroquine and Phlebotomy for Treating Porphyria Cutanea Tarda
• Sorbent Therapy of the Cutaneous Porphyrias
• Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda
• Pilot Trial of Deferasirox in the Treatment of Porphyria Cutanea Tarda
• Porphozym in the Treatment of Acute Attacks in AIP
• Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria
• Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria
• Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria
• Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias
• Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks