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Clinical Trials for Vaso-Occlusive Crises

• Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease
• Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care
• Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
• Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis
• A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
• Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
• Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease
• A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
• Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department