"Clinical Trial to Determine the Efficacy of Vitamin D for Acne Therapy"

• Status: Completed
• Trial end date: 2014-01-09
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to study the effects of topical Vitamin D cream (Calcipotriene, also known as Dovonex) on acne. The information gained from this study may lead to new treatments for acne. In this study, Calcipotriene will be compared with a placebo, a cream that looks like Calcipotriene, but contains no active ingredients.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, Los Angeles
• Collaborator: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Treatments: Calcipotriene; Calcitriol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

1. Age 18 years or older, of either gender and any racial/ethnic group

2. Subjects must have clinically evident mild to moderate acne vulgaris of the facial area, IGA scale, grade 2-4

3. Subjects must understand and sign the informed consent prior to participation

4. Subjects must be in generally good health

5. Subjects must be able and willing to comply with the requirements of the protocol

Exclusion Criteria:

1. Oral retinoid use within twelve months of entry into the study

2. Systemic acne therapies (oral antibiotics) within 30 days of entry into the study

3. Topical acne therapies (retinoids, antibiotics) within 14 days of entry into the study

4. Non-compliant patients

5. Pregnant or nursing women

6. Subjects with a significant medical history or concurrent condition that the investigator(s) feel is not safe for study participation

7. Subjects with hypercalcemia (hyperparathyroidism, kidney disease)

8. Subjects who cannot avoid excessive exposure to either natural or artificial sunlight.