Overview

"Steroids and Azathioprine Versus Steroids Alone in IgAN"

Status:
Completed
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
In a previous trial the investigators found that the effect of steroids in IgA nephropathy diminish over time. The difference in renal survival is striking up till the third year, but then remains constant. A six-month course of steroid therapy may be not enough to ensure a stable remission. The investigators hypothesized that a more aggressive treatment may obtain long-term better results. The investigators conducted a randomised controlled trial to assess the utility of low-dose azathioprine added to steroids in adult IgAN patients.
Phase:
Phase 4
Details
Lead Sponsor:
A. Manzoni Hospital
Treatments:
Azathioprine
Methylprednisolone
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Prednisone