"The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"
Status:
Not yet recruiting
Trial end date:
2023-07-30
Target enrollment:
Participant gender:
Summary
Several studies have attempted to calculate the ideal epinephrine concentration for
vasoconstriction, however there has been little consensus. These experiments were carried out
on animals, and the degree of vasoconstriction was measured using a variety of methods.
Animal studies aren't always reliable since animal capillary density differs from human
capillary density. Furthermore, because the density of capillaries in the head and neck is 30
to 40% higher than in other parts of the body, previous studies may not adequately reflect
the ideal epinephrine concentration for this highly vascular location. As a result of this
study, clinicians will be able to determine the appropriate dose of epinephrine to control
intraoperative bleeding. This study aims to determine the effect of different doses of
epinephrine on volume of bleeding in surgical incisions in participants undergoing
supraclavicular flap surgery.