rEduction of oXygen After Cardiac arresT: a Pilot Study

• Status: Completed
• Trial end date: 2017-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This Phase 2 study aims to determine the feasibility of paramedic titration of oxygen delivery in adult patients who have been resuscitated from OHCA.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Monash University
• Collaborators: Ambulance Victoria; Curtin University; Curtin University of Technology; Flinders University; SA Ambulance Service

Criteria

Inclusion Criteria:

• Adults (age ≥18 years)

• Out-of-hospital cardiac arrest of presumed cardiac cause

• Initial cardiac rhythm ventricular fibrillation/ ventricular tachycardia ("shockable")

• Unconscious (Glasgow Coma Scale <9)

• In cardiac arrest on ambulance arrival

• Sustained return of spontaneous circulation (>2 minutes)

• Pulse oximeter trace with oxygen saturation measured at ≥95% on bag/ reservoir with oxygen set at ≥10L/min

• Patient is spontaneous breathing or ventilated using bag/valve/oxygen reservoir via endotracheal tube or SGA (i.e. laryngeal mask airway)

Exclusion Criteria:

• Female who is known or suspected to be pregnant

• Dependant on others for activities of daily living (i.e. facilitated care or nursing home residents)

• "Not for Resuscitation" order

• EMS witnessed arrests