Overview

tSCI Contrast Enhanced Ultrasound Study

Status:
Recruiting

Trial end date:
2024-12-31

Target enrollment:
0

Participant gender:
All

Summary

Patients with traumatic spinal cord injury (tSCI) often suffer from spinal cord swelling inside the thecal sac, which contains the spinal cord and surrounding fluid, leading to increased pressure on the spinal cord tissue and decreased spinal cord blood flow at the site of injury. The combination of increased pressure and decreased blood flow causes vascular hypo-perfusion of the spinal cord and exacerbates the severity of injury. This is also referred to as secondary injury. Thus, knowledge of spinal cord hypo-perfusion would allow the treating physician to optimize the hemodynamic condition of patient with acute spinal cord injury and potentially improve functional outcome. We plan to use contrast-enhanced ultrasound (CEUS) to determine decrease of blood flow in the spinal cord at the site of injury, during the routine surgery that these patients require to decompress and stabilize their injured spine. This may help us to determine the efficacy of certain treatments in improving blood flow and patients suffering from tSCI.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Washington

Criteria

Inclusion Criteria:

>18 Male or Female Acute <72 hours spinal cord injury American Spinal Injury Association
(ASIA) grade A to D Medically stable to undergo routine decompression and spinal
realignment

Exclusion Criteria:

<18 years of age Not clinically stable for spinal surgery Traumatic Brain Injury