the Effect of Different Drugs and Infusion Ways on Degree of Postoperative Comfort

• Status: Completed
• Trial end date: 2020-10-30
• Target enrollment: 0
• Participant gender: All

Summary

To explore the effect of different drugs and infusion ways on degree of postoperative comfort.Patients undergoing spinal neoplasm surgery receive different patient controlled analgesia(PCA) drugs postoperatively,one group is sufentanil,the other is hydromorphone. Then each drug group will be divided into two subgroups according to the infusion way,intravenously,subcutaneously. During the patient controlled analgesia period, patients' degree of comfort,pain score,sleep quality, the degree of side reaction will be recorded.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Jun Wang
• Treatments: Dexmedetomidine; Dsuvia; Hydromorphone; Sufentanil

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical status I or II .

Exclusion Criteria:

• history of severe heart, hepatic or renal disease,

• history of chronic pain condition or opioid use,

• body mass index (BMI) ≤18 or ≥30 kg/m2,

• alcohol or drug abuse,

• relevant drug allergy,

• inability to properly describe postoperative pain,

• inability to use PCA pump.