Overview

the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation

Status:
Unknown status
Trial end date:
2018-07-30
Target enrollment:
0
Participant gender:
Female
Summary
assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications. Research question Does pre-operative misoprostol affect on intra-operative blood loss during and after myomectomy operation ?. Research hypothesis Pre-operative misoprostol may reduce intra-operative blood loss during and after myomectomy operation .
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
ahmed nagy shaker ramadan
Treatments:
Misoprostol
Criteria
Inclusion Criteria:

- Premenopausal patients aged between 35 to 50 years old.

- Five or less symptomatic uterine myomas .

- Maximum diameter of the largest myoma is 6 cm .

- All myomas are subserous or intramural.

- Uterine size less than 24 weeks pregnancy

Exclusion Criteria:

- History of previous surgery.

- Allergy to Misoprostol.

- Hypertension.

- Cardiac and Pulmonary diseases.

- Patients who have bleeding disorders.

- Anemia (Hb < 10g %).

- Chronic endocrine or metabolic diseases such as Diabetes.

- Obesity (body mass index > 30 kg/m2).

- Cases that will require intraoperative conversion of myomectomy to hysterectomy.