Overview
the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation
Status:
Unknown status
Unknown status
Trial end date:
2018-07-30
2018-07-30
Target enrollment:
0
0
Participant gender:
Female
Female
Summary
assess the effect of using misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications. Research question Does pre-operative misoprostol affect on intra-operative blood loss during and after myomectomy operation ?. Research hypothesis Pre-operative misoprostol may reduce intra-operative blood loss during and after myomectomy operation .Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
ahmed nagy shaker ramadanTreatments:
MisoprostolCriteria
Inclusion Criteria:- Premenopausal patients aged between 35 to 50 years old.
- Five or less symptomatic uterine myomas .
- Maximum diameter of the largest myoma is 6 cm .
- All myomas are subserous or intramural.
- Uterine size less than 24 weeks pregnancy
Exclusion Criteria:
- History of previous surgery.
- Allergy to Misoprostol.
- Hypertension.
- Cardiac and Pulmonary diseases.
- Patients who have bleeding disorders.
- Anemia (Hb < 10g %).
- Chronic endocrine or metabolic diseases such as Diabetes.
- Obesity (body mass index > 30 kg/m2).
- Cases that will require intraoperative conversion of myomectomy to hysterectomy.