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Clinical Trials for Mitochondrial Diseases

• MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
• OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)
• Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
• Applying pGz in Mitochondrial Disease
• A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease
• Study to Evaluate the Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease Resulting From Nuclear DNA Mutations (nPMD)
• The KHENERGYC Study
• Drug-drug Interaction Study of KL1333 in Healthy Subjects
• The KHENEREXT Study
• A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy
• The KHENERGYZE Study
• A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
• Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity
• Mitochondria and Chronic Kidney Disease
• Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
• Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)
• The KHENERGY Study
• Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study
• Sulfamethoxazole for the Treatment of Primary PREPL Deficiency
• A Dose-escalating Clinical Trial With KH176
• Fatty Acid Oxidation Defects and Insulin Sensitivity
• Heart Rate Variability in Response to Metformin Challenge
• A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease
• A Study of Bezafibrate in Mitochondrial Myopathy
• Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy
• Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?
• Phase 2 Study of EPI-743 in Children With Pearson Syndrome
• Anesthesia in Patients With Mitochondrial Disease
• Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease
• Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
• EPI-743 for Metabolism or Mitochondrial Disorders
• Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism
• Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/Action
• EPI-743 for Mitochondrial Respiratory Chain Diseases
• Anesthetic Effects in Mitochondrial Disease
• Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects
• Phase III Trial of Coenzyme Q10 in Mitochondrial Disease
• RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease