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Clinical Trials for Restless Legs Syndrome

• Pitolisant in Refractory Restless Legs Syndrome
• Sublingual Apomorphine in Refractory Restless Legs Syndrome
• The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis
• Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy
• Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
• Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia
• Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder
• RCT for Pregabalin in Restless Legs Syndrome in South Korea
• A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo
• A Follow-up Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome
• Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients
• DIalysis Symptom COntrol-Restless Legs Syndrome Trial
• Treatment of Restless Legs Syndrome With the Hypocretin Antagonist Suvorexant
• A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown Cause
• Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD
• Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome
• Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
• Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
• Cholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney Disease
• A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients
• Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia
• Quality Improvement and Practice Based Research in Neurology Using the EMR
• Long-term Efficacy and Safety of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients
• The Effect of Horizant (Gabapentin Enacarbil) on Augmentation
• An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
• A PK and Safety Evaluation of HORIZANT (Gabapentin Enacarbil) in Adolescents With Moderate-to-Severe Primary RLS
• An Efficacy and Safety Evaluation of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
• Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)
• IV Iron Treatment of Restless Legs Syndrome
• Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome
• Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS
• Vitamin D in the Treatment of Primary Restless Legs Syndrome
• Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS)
• Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS)
• Study to Investigate Pharmacokinetics (PK) of Pramipexole in Pediatric Patients Who Are Individually Optimized to Stable Pramipexole Doses for the Treatment of Idiopathic Restless Legs Syndrome (RLS)
• Butrans for Treatment of Restless Legs Syndrome
• Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome
• Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome
• Post-marketing Study of Gabapentin Enacarbil to Evaluate the Effect in Restless Leg Syndrome (RLS) Patients With Moderate Renal Impairment
• Switching From Oral Dopamine Agonists to Rotigotine
• Targeting Dopamine Therapy in RLS
• Investigation of Efficacy of incobotulinumtoxinA (Xeomin) in Relieving Symptoms of Restless Leg Syndrome.
• Specified Drug Use-Results Survey of Regnite
• Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome
• Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study
• Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs Syndrome (RLS)
• A Long-Term Extension Trial From Late Phase II of SPM 962 in Patients With Restless Legs Syndrome
• A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis
• Safety and Efficacy Study of IPX159 in Restless Legs Syndrome (RLS)
• A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers
• Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Legs Syndrome
• Dose Escalating Study of Rotigotine in Pediatric Subjects With Restless Legs Syndrome
• Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine
• Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome
• Study to Assess the Effect of Gabapentin Enacarbil on Simulated Driving in Healthy Subjects
• Intravenous (IV) Iron Preparation (VIT-45) in the Treatment of Restless Legs Syndrome (RLS)
• Simulated Driving Study in Restless Legs Syndrome
• Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs Syndrome
• REQUIP RLS Post Marketing Surveillance
• Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy
• Safety and Efficacy of Rasagiline in Restless Legs Syndrome
• Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
• Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients
• Non-interventional Study (NIS) in Patients With Restless Legs Syndrome in Daily Practise
• Oxycodone/Naloxone Prolonged Release (OXN PR) Compared to Placebo to Demonstrate Improvement in Symptoms of Restless Legs Syndrome (RLS) in Subjects With Moderate to Severe Idiopathic RLS With Daytime Symptoms
• Study of SPM 962 in Patients With Restless Legs Syndrome (RLS)
• 12-Week Efficacy And Safety Of Pregabalin In Treating Restless Legs Syndrome (RLS) Subjects
• Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemo
• Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance
• Restless Legs Syndrome Treatment With Botulinum Toxin
• Iron Sucrose In The Treatment of Restless Legs Syndrome: Safety of Three Dose Regimens as Evaluated by Clinical Assessments
• Efficacy and Safety Study of Aplindore in Patients With Restless Legs Syndrome
• Long Term Study Of Pregabalin In Idiopathic Restless Legs Syndrome Patients
• Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Disturbance
• Sifrol (Pramipexole) Onset of Action and Impact: a 12-weeks Observational Study in Patients With Primary Restless Legs Syndrome
• Intravenous Iron Metabolism in Restless Legs Syndrome
• Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients
• A Single-Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Ropinirole 0.25 mg Tablets Under Fed Conditions
• A Single Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Ropinirole 0.25 mg Tablets Und Fasted Conditions
• A Placebo-Controlled Study for SPM 962 in Restless Legs Syndrome (RLS) Patients
• Neuroma Injections to Treat Restless Legs Syndrome - RCT
• Pramipexole in Out-patients With Idiopathic Restless Legs Syndrome (IRLS)
• A Study to Evaluate the Efficacy and Safety of Cabergoline Compared With Placebo for the Treatment of RLS
• The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome
• A Study to Determine the Efficacy and Safety of Cabergoline for the Treatment of Patients With RLS
• Bupropion and Restless Legs Syndrome
• Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome
• Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome
• ASP8825 - Study in Patients With Restless Legs Syndrome
• Long-term Open-label Trial in Idiopathic Restless Legs Syndrome (RLS)
• Phase 3 Open-label Extension Trial With Rotigotine in Idiopathic Restless Legs Syndrome Subjects
• Botulinum Toxin to Treat Restless Legs Syndrome
• Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS)
• A Study To Investigate The Effects Of End Stage Renal Disease And Hemodialysis On The Pharmacokinetics Of Ropinirole
• Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food
• A Randomised, Comparing Fixed Doses of Pramipexole to Investigate the Efficacy and Safety in Patients With RLS.
• Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of RLS Symptoms
• A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS
• 12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
• Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)
• XP13512 vs. Placebo in Patients With Restless Legs Syndrome.
• A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome
• The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrome
• Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Disturbances
• Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome
• A Phase IV Trial With Pramipexole to Investigate the Effects on RLS Symptoms and Sleep Disturbance in Patients With RLS
• SWITCH:Restless Legs Patients Switched to Ropinirole From Pramipexole
• XP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome.
• Long-term Study Of Ropinirole In Restless Legs Syndrome
• RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole
• Long-Term Study of Gabapentin Enacarbil (GEn, XP13512) vs. Placebo in Patients With Restless Legs Syndrome.
• XP13512 (GSK1838262) Versus Placebo in Patients With Restless Legs Syndrome.
• Efficacy and Safety of Pramipexole (PPX) in Moderate to Severe Idiopathic Restless Legs Syndrome (RLS) Patients
• A Sleep Lab Trial to Investigate the Efficacy and Safety of Transdermal Rotigotine in Subjects With Idiopathic Restless Legs Syndrome
• An Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs Syndrome
• Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)
• A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)
• Rotigotine Restless Legs Syndrome Dose Finding Trial
• Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS)
• A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS)
• Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome
• Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome
• Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome
• Pramipexole (BI-Sifrol®) Orally Once Daily for 6 Weeks in Patients With Primary Restless Legs Syndrome
• A Study in Patients Suffering From Idiopathic Restless Legs Syndrome Who Responded to a Preceding, 6-month Treatment With Open-label Pramipexole Including Titration (0.125, 0.25, 0.5, 0.75 mg Orally q.n.)
• Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in Patients With Restless Legs Syndrome
• Ropinirole Tablets In Young Patients With Restless Legs Syndrome
• Three Different Transdermal Doses of Rotigotine in Subjects With Idiopathic Restless Leg Syndrome
• Four Different Transdermal Doses of Rotigotine in Subjects With Idiopathic Restless Legs Syndrome
• Efficacy and Safety of Pramipexole Compared to Placebo in the Treatment of Restless Legs Syndrome (RLS)