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Clinical Trials for Severe Combined Immunodeficiency

• Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus
• Safety and Efficacy Study of Human T Lymphoid Progenitor (HTLP) Injection After Partially HLA Compatible Allogeneic Hematopoietic Stem Cell Transplantation in SCID Patients
• Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID
• Conditioning SCID Infants Diagnosed Early
• Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency
• Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)
• Autologous Gene Therapy for Artemis-Deficient SCID
• Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
• Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency
• Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID
• Sirolimus Prophylaxis for aGVHD in TME SCID
• Immune Disorder HSCT Protocol
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
• Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
• Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
• Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
• Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim
• Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases
• Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders
• Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1
• IMM 0212: Busulfan With Fludarabine and Antithymocyte Globulin as Preparative Therapy for Hematopoietic Stem Cell Transplant for the Treatment of Severe Congenital T-Cell Immunodeficiency
• Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients
• Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome
• Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)
• Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency
• Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant
• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
• Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study