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Clinical Trials for Tuberous Sclerosis

• Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
• A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex
• Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy (TrustTSC OLE)
• Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC
• Feasibility of [11C]Acetate-Positron Emission Tomography (PET) in Lymphangioleiomyomatosis and Tuberous Sclerosis Complex
• Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy
• A Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
• Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
• Basimglurant in Children and Adolescents With TSC
• Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
• Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants
• Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants
• Safety, Pharmacokinetics, and Exploratory Efficacy Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) Compared With Standard of Care Antiepileptic Therapy, in Patients Age 1 Month to <12 Months of Age With Tuberous Sclerosis Complex Who
• Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)
• Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex
• Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.
• Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
• Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex
• Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis
• Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
• Topical Everolimus in Patients With Tuberous Sclerosis Complex
• Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex
• Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
• Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
• A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
• An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
• A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
• Everolimus for Cancer With TSC1 or TSC2 Mutation
• Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers
• Safety of Simvastatin in LAM and TSC
• A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis
• Rapalogues for Autism Phenotype in TSC: A Feasibility Study
• Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
• Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
• A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures
• Topical Rapamycin to Erase Angiofibromas in TSC
• Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
• Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients
• Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis
• Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
• Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
• Doxycycline In Lymphangioleiomyomatosis (LAM)
• Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)
• Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
• Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
• Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
• RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
• Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
• Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex