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Clinical Trials for Vulvar Neoplasms

• A PHASE II, RANDOMIZED TRIAL TO ASSESS MAINTENANCE THERAPY WITH CEMIPLIMAB VERSUS BEST SUPPORTIVE CARE AFTER 1ST LINE PLATINUM-BASED CHEMOTHERAPY IN ADVANCED/RECURRENT VULVAR CANCER
• Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors
• Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery
• ECT STUDY High-grade or Initially Invasive Vulva - GinOnc-ECT Study
• HPV Vaccine, Imiquimod, and Metformin Combination Trial
• [177Lu]Lu-AKIR001 First-in-human Study
• Agnostic Therapy in Rare Solid Tumors
• Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma
• Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
• A Phase II, Single-arm, Multicenter, Prospective Study of Cardunolizumab in Recurrent or Metastatic Vulvar and Vaginal Cancer
• MRI and Magnetometer-guided Sentinel Lymph Node Detection in Vulvar Cancer
• Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor
• A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)
• HRYZ-T101 Injection for HPV18 Positive Solid Tumor
• AK104 for Recurrent or Metastatic Vulvar Cancer
• Electrochemotherapy for the Treatment of Vulvar Cancer
• Primary Chemoradiation VS. Neoadjuvant Chemotherapy Followed By Surgery As Treatment Strategy For LAVC
• Pembrolizumab in Combination With Lenvatinib in Patients With Recurrent, Persistent, Metastatic or Locally Advanced Vulvar Cancer Not Amenable to Curative Surgery or Radiotherapy
• Neo-adjuvant Pembrolizumab in Vulvar Squamous Cell Carcinoma: a Clinical Proof-of-concept Study
• E7 TCR-T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
• Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
• Electrochemotherapy With Carboplatinum Plus Bleomycin Versus Bleomycin Alone in Vulvar Cancer
• Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery
• Contrast-Enhanced Ultrasound Imaging Scan for the Detection of Sentinel Lymph Nodes in Patients With Cervical, Vaginal, or Vulvar Cancer
• Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
• Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
• Cisplatin+Pembrolizumab+RT in Vulvar Cancer
• Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations
• Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize)
• Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery
• Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy
• Stereotactic Ablative Radiotherapy (SABR) in Combination With Durvalumab and Tremelimumab in Patients With Cervical, Vaginal, or Vulvar Cancer
• Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer
• PEN-866 in Patients With Advanced Solid Malignancies
• Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)
• Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer
• Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery
• A Phase 1/2 Study to Investigate the Safety, Biologic and Anti-tumor Activity of ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies
• E7 TCR T Cells for Human Papillomavirus-Associated Cancers
• Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer
• HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA
• Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer
• Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva
• Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery
• Safety Study Of Avastin And Pelvic Radiation In Women With Recurrent Gynecological Cancers
• Broad Spectrum HPV (Human Papillomavirus) Vaccine in 16 to 26 Year Old Women (V505-001)
• Topical Imiquimod in Treating Patients With Recurrent Paget's Disease of the Vulva
• Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity of the Fungicide Ciclopirox.
• Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer
• Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic Malignancies
• Docetaxel in Treating Patients With Refractory or Recurrent Advanced Gynecologic Cancer
• Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva
• Octreotide in Preventing Diarrhea in Patients Who Are Undergoing Radiation Therapy to the Pelvis
• Fibrin Sealant in Decreasing Lymphedema Following Surgery to Remove Lymph Nodes in Patients With Cancer of the Vulva
• Paclitaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Cancer of the Vulva
• Radiation Therapy With or Without Cisplatin in Treating Patients With Stage I, Stage II, or Stage III Cancer of the Vulva
• Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or Vulva