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Clinical Trials for Hemoglobinopathies

• Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies
• Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
• Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study
• Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant
• A Blood Stem Cell Transplant for Sickle Cell Disease
• Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
• Fetal Hemoglobin Induction Treatment Metformin
• HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity
• Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases
• Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies
• Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease
• Safety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant
• Non-Myeloablative Conditioning and Bone Marrow Transplantation
• Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients
• Pharmacokinetic Study of Deferiprone in Paediatric Patients
• Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
• Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies
• Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
• Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
• Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies
• Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders
• Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload
• Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP
• Stem Cell Transplant for Hemoglobinopathy
• Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies
• Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies
• Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies
• Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
• Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes
• Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)
• Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG)
• Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis
• Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
• Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)
• Penicillin Prophylaxis in Sickle Cell Disease (PROPS)