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Clinical Trials for Hyperinsulinism

• Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy
• Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β
• A Pilot Study of Monitoring Insulin Levels and Treating Hyperinsulinemia and Hyperglycemia With Pioglitazone in Patients Treated With Alpelisib for Metastatic Breast Cancer.
• Effect of Alpelisib in Healthy Volunteers
• Glycemic Effect of Diazoxide in NAFLD
• Pancreatic Clamp in NAFLD
• Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes Mellitus
• Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
• Vitamin E Efficacy in HI/HA
• Exenatide-test for Diagnosing Endogenous Hyperinsulinemic Hypoglycemia
• HM15136 Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)
• 18F-DOPA II - PET Imaging Optimization
• Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia
• An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism
• Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
• Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance
• Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism
• Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
• Pasireotide in Hyperinsulinemic Hypoglycemia
• 18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety
• Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)
• CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism
• Compassionate Use of SOM230 for Hyperinsulinemic/Hypoglycemia
• Reprometabolic Syndrome Mediates Subfertility in Obesity
• Natriuretic Peptides and Metabolic Risk in Obesity
• A Single-Dose Open-Label Study of XOMA 358 in Subjects With Congenital Hyperinsulinism
• Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia
• Sirolimus for the Treatment of Hyperinsulinism
• PK/PD Study of U-500 Regular Insulin
• Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
• 18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia
• Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia
• The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension
• Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
• Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of Infancy
• Sandostatine® LP and Hyperinsulinism
• Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
• Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia
• Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism
• Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
• EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance
• Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism
• Diazoxide-Mediated Insulin Suppression in Hyperinsulinemic Obese Men
• Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities
• Metformin to Treat Obesity in Children With Insulin Resistance
• Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome
• Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome
• Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
• Phase II Long Term, Randomized Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
• Dose Ranging Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism
• Effect of Insulin on Endothelin-Dependent Vascular Tone in the Forearm Circulation