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Clinical Trials for Leishmaniasis

• Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults
• LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study
• Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis
• A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis
• Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis
• Treatment of Mucosal Bolivian Leishmaniasis
• Combination, Miltefosine Monotherapy & Antimonial Therapy for Cutaneous Leishmaniasis in New World
• Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants
• Efficacy of Intra-lesional Injections of Glucantime Once a Week or Twice a Week in the Treatment of Anthroponotic Cutaneous Leishmaniasis (ACL)
• Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis.
• Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects
• Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy Subjects
• Oral Miltefosine Plus Topical Paromomycin In American Cutaneous Leishmaniasis
• Steady State Global Bioequivalence Study of Amphotericin B Liposome for Injection 50 mg/ Vial in Fed Condition
• Miltefosine Plus IL Pentamidine for Bolivian CL
• Short Course Regimens for Treatment of PKDL (Sudan)
• Safety and Effectiveness of Short-course AmBisome in the Treatment of PKDL in Bangladesh
• Fourth-generation Immucillin Derivative DI4G Associated Therapy in Cutaneous Leishmaniasis
• Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa
• Topical Paromomycin for Cutaneous Leishmaniasis in Bolivia
• Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients
• Miltefosine and GM-CSF in Cutaneous Leishmaniasis
• Efficacy and Safety of Pentamidine (7mg/kg) for Patients With Cutaneous Leishmaniasis Caused by L. Guyanensis
• A Study of a New Leishmania Vaccine Candidate ChAd63-KH
• Thermotherapy + a Short Course of Miltefosine for the Treatment of Uncomplicated Cutaneous Leishmaniasis in the New World¨
• Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis
• The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil
• Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
• Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children in Eastern Africa
• Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
• Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient Registry
• Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy Registry
• Prospective Observational Study of Intralesional Treatment With Pentostam in Cutaneous Leishmaniasis Israeli Patients
• Miltefosine for Children With PKDL
• Liposomal Amphotericin in Disseminated Leishmaniasis
• Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.
• WR 279,396 for the Treatment of Cutaneous Leishmaniasis
• Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in Sudan
• A Study to Explore Association of Treatment Regimens for Visceral Leishmaniasis, Host Immunological, Genetical and Nutrition Factors With Post-kala-azar Dermal Leishmaniasis (PKDL)
• High Dose Fluconazole in Cutaneous Leishmaniasis in Bahia and Manaus
• Topical 3% Amphotericin B Cream for the Treatment of Cutaneous Leishmaniasis in Colombia
• Phase 3 Study of Walter Reed (WR) 279,396 and Paromomycin Alone for the Treatment of Cutaneous Leishmaniasis in Panama
• LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine
• Efficacy of Radio-frequency Induced Heat (RFH)Therapy in Treatment of Cutaneous Leishmaniasis in India
• Paromomycin for Individuals With Uncomplicated Cutaneous Leishmaniasis
• Single Dose Liposomal Amphotericin B for Visceral Leishmaniasis
• A Study to Evaluate the Efficacy and Tolerance of WR279,396 for Old World Cutaneous Leishmaniasis
• WR 279,396 Open Label Treatment Protocol in Tunisia
• Add-on Study of Pentoxifylline in Cutaneous Leishmaniasis
• Pharmacokinetics of Miltefosine in Children and Adults
• SCH708980 With and Without AmBisome for Visceral Leishmaniasis
• Antimony Plus Pentoxifylline in Cutaneous Leishmaniasis
• Oral Miltefosine Plus Topical Imiquimod to Treat Cutaneous Leishmaniasis
• Treatment of Cutaneous Leishmaniasis With a Combination of Miltefosine and Antimony
• Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis
• Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study
• An Effectiveness Study of Paromomycin IM Injection (PMIM) for the Treatment of Visceral Leishmaniasis (VL) in Bangladesh
• Efficacy and Safety Study of Drugs for Treatment of Visceral Leishmaniasis in Brazil
• Low Antimonial Dosage in American Mucosal Leishmaniasis
• Comparison of Standard and Alternative Antimonial Dosage in Patients With American Cutaneous Leishmaniasis
• Intralesional Antimony for Bolivian Cutaneous Leishmaniasis
• A Pilot Study for Capacity Building for a Multi-centre, Randomized Trial for Treatment of Kala Azar in Bangladesh
• Safety, Efficacy, and PK of Topical Paromomycin/Gentamicin Cream for Treatment of Cutaneous Leishmaniasis
• Immune Response of Visceral Leishmaniasis PatientsTreated With Antimonial Plus N-Acetylcysteine
• Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh
• Pharmacokinetics, Safety, and Efficacy Trial of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream for the Treatment of Cutaneous Leishmaniasis in Panama
• A Community Trial for Visceral Leishmaniasis (VL)
• Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa
• Miltefosine to Treat Mucocutaneous Leishmaniasis
• Efficacy of Topical Liposomal Form of Drugs in Cutaneous Leishmaniasis
• Safety, Efficacy and Pharmacokinetics (PK) Study of WR 279,396 Versus Paromomycin for Treatment of Cutaneous Leishmaniasis (Peru-PK)
• Amphotericin B to Treat Visceral Leishmaniasis in Brazilian Children
• A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis
• Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients
• Reduced Doses of Antimony Plus Ranulocyte Monocyte Colony Stimulating Factor (GM-CSF) for Cutaneous Leishmaniasis
• Rationale for New Topical Anthroponotic Cutaneous Leishmaniasis (ACL) Treatment in Kabul
• Local Heat Therapy Versus Sodium Stibogluconate for the Treatment of Cutaneous Leishmaniasis
• To Study the Effect Of Single Infusions Of Amphotericin B Lipid Preparations in Treatment of Patients Of Kala Azar
• Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Patients With VL
• Low-dose Pentavalent Antimony Treatment of Cutaneous Leishmaniasis in Old Age Patients
• Topical Treatment of Cutaneous Leishmaniasis With WR 279,396: A Phase 2 Study in the Old World
• Safety and Efficacy Study to Evaluate Different Combination Treatment Regimens for Visceral Leishmaniasis
• Safety and Efficacy of Azithromycin to Treat Cutaneous Leishmaniasis
• Sodium Stibogluconate Treatment of Leishmaniasis
• Topical Treatment of Recalcitrant Ulcerative Old World Leishmaniasis With WR 279,396
• Use of Sodium Stibogluconate as a Treatment for Leishmaniasis
• An Open Lable Randomised Study to Assess the Safety and Efficacy of Short Course Paromomycin in Visceral Leishmaniasis
• Single Infusion of Liposomal Amphotericin B in Indian Visceral Leishmaniasis
• Phase 3 Study to Evaluate WR 279,396 vs. Paromomycin Alone to Treat Cutaneous Leishmaniasis (in Tunisia)
• Expand Access/Assess Safety and Efficacy of Paromomycin IM Injection for the Treatment of Visceral Leishmaniasis
• Trial of Miltefosine in Cutaneous Leishmaniasis (Brazil)
• Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia
• Combination Therapy in Indian Visceral Leishmaniasis
• Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
• A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar
• Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application
• Oral Miltefosine for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia
• Treatment of Cutaneous Leishmaniasis With Meglumine Antimoniate Versus Meglumine Antimoniate and Allopurinol
• Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia.
• Antihelminthic Therapy Combined With Antimony in the Treatment of Cutaneous Leishmaniasis
• A Study Evaluating Sitamaquine Compared With Amphotericin B In The Treatment Of Visceral Leishmaniasis.
• Miltefosine for Brazilian Visceral Leishmaniasis
• Miltefosine for Mucosal Leishmaniasis
• Miltefosine (Long Course) for Bolivian Mucosal Leishmaniasis
• Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar
• Combination Chemotherapy for the Treatment of Indian Kala-Azar
• Efficacy Trial on Oral Miltefosine in Comparison With Glucantime in the Treatment of ACL Caused by L. Tropica
• Safety and Efficacy of Low-Dose Pentavalent Antimony for Treatment of Cutaneous Leishmaniasis
• Controlled Nitric Oxide Releasing Patch Versus Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis
• Amphotericin B Treatment in Visceral Leishmaniasis
• Imiquimod Plus Antimony Immunochemotherapy for Cutaneous Leishmaniasis
• Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis
• Miltefosine to Treat Cutaneous Leishmaniasis in Bolivia
• Safety and Efficacy Study of Paromomycin to Treat Visceral Leishmaniasis
• Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil