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Clinical Trials for Carcinoma in Situ

• Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
• Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma
• Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
• DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
• A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
• Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
• A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia
• Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)
• Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL
• A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia
• 5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
• A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)
• Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer
• Lopinavir/Ritonavir in PLWH With High-Grade AIN
• Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia
• Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)
• Metformin and Nightly Fasting in Women With Early Breast Cancer
• A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)
• A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCC
• Study of ONCOFID-P-B™ (PACLITAXEL-HYALURONIC ACID)
• Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ
• Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
• Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia or Lobular Carcinoma In Situ
• The Effectiveness of High Resolution Microendoscopy for People Living With HIV
• Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC
• The Ultrasound-guided Multiple-injection Costotransverse Block for Mastectomy and Primary Reconstructive Surgery.
• Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer
• HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
• Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males
• Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ
• Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast
• Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer
• HPV-SAVE: 9-Valent HPV Vaccine for High-Grade Anal Dysplasia
• Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9
• Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices
• Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)
• Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer
• Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS
• Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.
• Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
• Study of Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer
• Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
• Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer
• TMTP1-ICG Mapping in Colposcopy-directed Biopsy
• Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery
• Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer
• A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3)
• IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3
• Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection
• Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
• Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
• Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia
• Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer
• Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)
• Biweekly SOLAR, as First-line C/T in Pts With Gastric, Pancreatic and Biliary Cancers
• Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN)
• Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)
• Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer
• Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast
• A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.
• Oxybutynin Chloride in Managing Hot Flashes
• Ruxolitinib for Premalignant Breast Disease
• Imiquimod Treatment of High-grade CIN
• Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder
• Study of Pembrolizumab (MK-3475) for High Risk Oral Intra-Epithelial Neoplasias
• Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer
• Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3)
• E7 TCR T Cells for Human Papillomavirus-Associated Cancers
• Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
• Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder Cancer
• PDT Plus Vitamin D3 for Anal Dysplasia
• The PROMISE Study: Duavee in Women With DCIS
• Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol
• Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer
• Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1)
• The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP)
• Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVIN
• Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs)
• A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant
• Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization
• Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)
• MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ
• Imiquimod Treatment of CIN Lesions
• Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy
• Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia
• Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
• Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia
• Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3)
• Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer
• Topical or Ablative Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Squamous Intraepithelial Lesions
• Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix
• Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer
• HPV (Human Papilloma Virus) Vaccination After Treatment of Anal Intraepithelial Neoplasia (AIN)
• Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions
• Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction
• A Prospective, With One Site, Open-label Not Controled Trial, for the Observation of Treatment With CIDOFOVIR 1%, 3 Nights Per Week, During 4 Weeks, of Anal Intraepithelial Neoplasia, High Level, in HIV+ Patients
• A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia
• Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia
• Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
• Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer
• Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia
• Docosahexaenoic Acid in Preventing Recurrence in Breast Cancer Survivors
• Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia
• Broccoli Sprout Extract in Treating Patients With Breast Cancer
• Study With TMX-101 in Patients With Carcinoma In Situ (CIS) Bladder Cancer
• SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
• "Phase II Study of PET Guided Neoadjuvant Chemotherapy (NAC) and Oncotype Guided Hormonal Therapy of Breast Cancer"
• Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.
• Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in Situ
• Diagnostic Study of Early Breast Cancer Using Ultrasound
• Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasia
• Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor: A Proof of Principle Trial
• Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor
• Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia
• Indirect Comparison Topotecan Cervical Carcinoma
• Intravesical AD 32 (Valrubicin) in Patients With Carcinoma in Situ (CIS) of the Bladder Who Have Failed or Have Recurrence Following Treatment With Bacillus Calmette-guerin (BCG)
• Multi-center Study to Evaluate the Efficacy and Safety of Maintenance Therapy With Valrubicin Versus no Maintenance, in Subjects Treated With Valrubicin Induction for Carcinoma in Situ (CIS) of the Bladder
• Safety and Efficacy Study of Antiviral Local Application to Treat High Grade Cervical Intraepithelial Lesions (CIN2/3)
• Hormone Therapy Or Chemotherapy Before Surgery Based on Gene Expression Analysis in Treating Patients With Breast Cancer
• Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia
• Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
• RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the Bladder
• Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia
• Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms
• Clinical Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention
• Meta-analysis of Efficacy of Topotecan
• A Trial of Photodynamic Therapy With HPPH for Treatment of Dysplasia, Carcinoma in Situ and T1 Carcinoma of the Oral Cavity and/or Oropharynx
• Preoperative Testing of the Anti-Progesterone Mifepristone in Early Stage Breast Cancer
• An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+
• Letrozole in Preventing Breast Cancer in Healthy Postmenopausal Women at High Risk for Breast Cancer
• A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ
• Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial)
• A Study of RO5217790 in Participants With High Grade Cervical Intraepithelial Neoplasia (CIN) Associated With High Risk Human Papillomavirus (HR-HPV) Infection
• Safety and Tolerability of Cidofovir Gel Applied on Cervix Squamous Lesions
• Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)
• 4-Hydroxytamoxifen or Tamoxifen Citrate in Treating Women With Newly Diagnosed Ductal Breast Carcinoma in Situ
• Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod Treatment
• ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial
• Lapatinib for Treatment of Ductal Carcinoma In Situ (DCIS) of the Breast
• Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast
• Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving Tamoxifen
• Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) of Cervical Intraepithelial Neoplasia (CIN) Grade 1
• Doxorubicin Hydrochloride Liposome in Treating Women With Ductal Carcinoma in Situ Undergoing Surgery
• Photodynamic Therapy Using HPPH in Treating Patients With Recurrent Dysplasia, Carcinoma in Situ, or Stage I Oral Cavity Cancer
• Study Of Intraductal Carboplatin In Women With Ductal Carcinoma In Situ (DCIS)
• A Phase I Prevention Study of Atorvastatin in Women at Increased Risk for Breast Cancer
• A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL)
• Study of Polyphenon E in Men With High-grade Prostatic Intraepithelial Neoplasia
• Lapatinib Ditosylate in Treating Patients With Ductal Breast Carcinoma In Situ
• Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia
• Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast
• Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ
• Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ
• Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer
• Effect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, Stage II, Stage III Breast Cancer, or Ductal Carcinoma In Situ That Can Be Removed By Surgery
• Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer
• Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Cutaneous Squamous Cell Carcinoma In Situ
• Risedronate in Improving Bone Mineral Density and Bone Health in Postmenopausal Women With Ductal Carcinoma In Situ Enrolled in Clinical Trial CRUK-IBIS-II-DCIS
• Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia
• Tamoxifen or Letrozole in Treating Women With Ductal Carcinoma in Situ
• Internal Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ
• Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix
• Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II
• A Trial for Patients With Advanced/Recurrent Cervical Cancer
• A Pilot Clinical Trial to Evaluate the Biological Activity of Fulvestrant in Breast Ductal Carcinoma in Situ (DCIS)
• A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia
• A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia
• Fulvestrant or Tamoxifen in Treating Postmenopausal Women Who Are Undergoing Surgery for Ductal Carcinoma in Situ of the Breast
• Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia)
• Gefitinib Followed By Surgery in Treating Women With Ductal Carcinoma In Situ of the Breast
• Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
• Adjuvant Radiation Therapy Compared With Observation After Surgery in Treating Women With Estrogen Receptor Positive or Progesterone Receptor Positive Ductal Carcinoma In Situ of the Breast Who Are Receiving Tamoxifen or Anastrozole
• S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of the Cervix
• Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
• Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation Therapy
• Cystoscopy and Hexyl 5-Aminolevulinate in Detecting Carcinoma In Situ in Patients With Bladder Cancer
• A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN)
• Eflornithine To Prevent Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia
• Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia
• Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ