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Clinical Trials for Central Nervous System Diseases

• Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke
• A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
• Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age
• A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population
• An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease
• A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)
• Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer
• Propranolol on Post Stroke Immune Status and Infection
• Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation
• Study to Assess the Efficacy of XPro™ in Patients With Mild Alzheimer's Disease With Biomarkers of Inflammation
• For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.
• Phase 1 ALKS 1140 in Healthy Adults
• Dopaminergic Therapy for Frontotemporal Dementia Patients
• An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE
• Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia
• Adjunctive Use of Fute (Flupentixol) in Multi-acting Receptor-targeted Antipsychotics Treated Schizophrenia Patients
• Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's Disease
• A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
• XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy
• Blood-Brain Barrier Penetration of Therapeutic Agents in Human
• TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases
• Impact Dexmedetomidine on Postoperative Delirium in Patients After Intracranial Operation for Brain Tumor
• Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
• Dexmedetomidine for Prevention of Postoperative Delirium After Intracranial Operation for Brain Tumor
• The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients
• 1H Magnetic Resonance Spectroscopy in Migraine Patients
• CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)
• Is Sphenopalatine Ganglion Block Treatment Effective on Postspinal Headaches
• Fluoxetine Opens Window to Improve Motor Recovery After Stroke
• Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
• The Preventive Treatment of Migraine With Low-Dose Naltrexone and Acetaminophen Combination
• AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's Disease
• ACTHAR Therapy for Central Nervous System Sarcoidosis
• Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma
• General Anesthesia for Endovascular Thrombectomy; A Pilot Study.
• Retrospective Study of MRI in Pediatric Patients
• Testosterone Plus Finasteride Treatment After Spinal Cord Injury
• A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
• Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia
• Dexmedetomidine in Patients After Intracranial Surgery
• Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China
• Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions
• Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease
• Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia
• Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma
• DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas
• Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease
• Safety and Efficacy of Gadobutrol 1.0 Molar (Gadavist) in Patients for Central Nervous System (CNS) Imaging
• A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
• Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging
• Follow Up Safety Study of SCH 420814 in Subjects With Parkinson's Disease (P05175)
• ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases
• Dyskinesia in Parkinson's Disease (Study P04501)
• Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients
• Safety and Efficacy of MultiHance in Pediatric Patients
• Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System Disease