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Clinical Trials for Diffuse Intrinsic Pontine Glioma

• Study of Olutasidenib and Temozolomide in HGG
• Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
• Study of Ribociclib and Everolimus in HGG and DIPG
• FUS Etoposide for DMG - A Feasibility Study
• Oral AMXT 1501 Dicaprate in Combination With IV DFMO
• Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
• Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors or Meningiomas Expressing SST2A
• A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma and H3 K27M-Mutant High-Grade Glioma
• PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
• 131I-omburtamab Delivered by Convection-Enhanced Delivery in Patients With Diffuse Intrinsic Pontine Glioma
• Combination Therapy for the Treatment of Diffuse Midline Gliomas
• rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG
• CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma
• Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)
• A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)
• Nimotuzumab in Combined With Concurrent Radiochemotherapy in the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Children
• Phase I Study of Marizomib + Panobinostat for Children With DIPG
• CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas
• A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma
• 9-ING-41 in Pediatric Patients With Refractory Malignancies.
• GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
• Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma
• Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
• Fimepinostat in Treating Brain Tumors in Children and Young Adults
• Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
• Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas
• REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
• A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas
• Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses
• A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
• Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
• MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
• ONC201 in Pediatric H3 K27M Gliomas
• Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
• Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
• A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
• A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG
• International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)
• CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)
• Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
• H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas
• Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
• Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma
• A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas
• Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
• Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
• A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy
• Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
• Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma
• Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
• Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
• Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22
• A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
• Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
• Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
• Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents
• Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma
• PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
• Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
• Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
• Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
• Cilengitide in Combination With Irradiation in Children With Diffuse Intrinsic Pontine Glioma
• Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)
• A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
• Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma