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Clinical Trials for Hyponatremia

• To Study Effect of the Combination of Midodrine and Tolvaptan Versus Tolvaptan Alone in Patients With Severe Hyponatremia in Cirrhosis(TOLMINA Trial)
• Urea for Chronic Hyponatremia
• Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage
• Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia
• Early Sodium Intake in Preterm Newborns
• Albumin for Management of Hypervolemic Hyponatremia (AlbuCAT)
• Prophylaxis Versus Treatment for TURP Syndrome.
• The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.
• Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study
• A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH
• Tolvaptan for Advanced or Refractory Heart Failure
• Intravenous Fluids in Hospitalised Children
• Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients
• Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study
• Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium
• Regional Tolvaptan Registry
• Tolvaptan for Patients With Acute Neurological Injuries
• International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia
• A Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic Hyponatremia
• Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage:
• Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure
• Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances
• Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients
• V2 Receptor Effects on Fluid Regulation and Performance
• An Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic Hyponatremia
• Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia
• Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia
• Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia
• Efficacy and Safety of Tolvaptan in Cirrhotic Patients With Hyponatremia
• Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites
• Effect of Tolvaptan on Cognitive Function in Cirrhosis
• Effect of Samsca on Control of Hyponatremia and Extracellular Fluid in Cirrhotic Patients With Ascites
• Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia
• A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia
• Fractional Urate Excretion in Nonedematous Hyponatremia
• Tolvaptan for In-hospital Hyponatremia
• 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children
• Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS
• Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children
• Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical Practice
• Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia
• Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function
• Pico-Salax Colonic Preparation Study: Quantifying Electrolyte and Volume Status Changes
• International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
• A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia
• Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function
• Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)
• Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation
• Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial
• A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia
• Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
• Safety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological Patients
• A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia
• Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia
• 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children
• Maintenance Intravenous Fluids in Children
• THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation
• Hypertonic Saline Solution in Heart Failure
• Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients
• Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascites
• Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia
• Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
• A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
• Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia
• An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia
• DILIPO (DILutIonal HyPOnatremia)
• Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion
• Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion
• "SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
• "SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
• Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion