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Clinical Trials for Aspergillosis

• A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis
• Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations
• A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus
• Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and Allergic Bronchopulmonary Aspergillosis
• Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study
• Oral Itraconazole Versus Combination of Systemic Glucorticoids and Oral Itraconazole in CPA-ABPA Overlap Syndrome
• Safety and Efficacy of PC945 in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis
• A Prospective Study on Optimizing Treatment for ABPA
• Olorofim Aspergillus Infection Study
• PC945 Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients
• A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection
• Azole-echinocandin Combination Therapy for Invasive Aspergillosis
• A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment naïve Subjects With Chronic Pulmonary Aspergillosis
• Isavuconazole for the Prevention of COVID-19-associated Pulmonary Aspergillosis
• A Study to Evaluate the Efficacy and Safety of Dupilumab in Participants With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)
• Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study)
• Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects
• Deflazacort vs. Prednisolone in Acute-stage ABPA
• Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis
• Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)
• Benralizumab in the Treatment of Patients With Severe Asthma With ABPA
• Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA
• The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients.
• The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis
• PTX3-targeted Antifungal Prophylaxis
• A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants
• The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases
• CYP2C19 Genotype-Specific Dosing Plus TDM on Reaching Therapeutic Voriconazole Blood Levels
• Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants
• Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis
• Chronic Pulmonary Aspergillosis and Ambisome Aerosol With Itraconazole
• Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients
• Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects
• VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults
• A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma
• Drug/Drug Interactions With F901318
• Pharmacokinetics of IV Formulation
• Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment
• Radiolabelled IV and Oral Metabolism Study of F901318
• Invasives Aspergillosis in Acute Myeloid Leukemia
• Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patients
• Evaluation of Immediate Release Tablet
• Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects
• Study of Potential for Interaction of Fluconazole With F901318
• A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945
• Evaluation of the Potential for Cytochrome P450 3A4 Inhibition by F901318 Using Oral Midazolam as a Probe
• Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp
• Post Marketing Study to Evaluate the Efficacy and Safety of Micafungin Treatment on Invasive Aspergillosis
• Phase I Clinical Trial for Comparison of Pharmacokinetic Characteristics of Vorico Injection 200mg(Voriconazole) and Vfend® IV 200mg for Single Dose Crossover Intravenous Infusion in Healthy Volunteers
• A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis
• Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration
• Single Ascending Oral Dose Study of F901318
• F901318 Multiple Ascending Dose Study
• Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded).
• Voriconazole for IPA in Chinese Patients With COPD
• Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)
• F901318 Single Ascending Dose Study in Healthy Male Volunteers
• CYP 2C19 Polymorphism and Voriconazole Trough Concentration in Chinese Adult Patients
• Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy
• A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis
• A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)
• Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis
• Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia
• ATCF (Azole Therapy in Cystic Fibrosis)
• Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease
• Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To Less Than 15 Years Old Who Are At High Risk For Systemic Fungal Infection
• Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis
• Efficacy Of Itraconazole In Chronic Cavitary Pulmonary Aspergillosis
• Trial of Combination Antifungal Therapy (Vori+Mica vs. Vori+Placebo) in Invasive Aspergillosis
• Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects
• A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074)
• Voriconazole Trough Plasma Levels : Genetic Polymorphism, Efficacy, Safety in Patients With Hematologic Malignancy
• Efficacy, Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis
• Influence of Drug-drug Interactions on the Pharmacokinetics (PK) of Voriconazole
• Value of Amphotericin B Inhalation for Prophylaxis of Invasive Pulmonary Aspergillosis After Renal Transplantation
• Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients
• Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis
• A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects
• A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children
• An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)
• A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection
• A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)
• A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections
• Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi
• Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene)
• Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis
• Prophylaxis of Fungal Invasive Infections in Leukemia
• A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis
• Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis
• Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis
• Nebulized Liposomal Amphotericin B Ambisome for Prophylaxis of Invasive Pulmonary Aspergillosis
• Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection
• Micafungin Salvage Mono-therapy in Invasive Aspergillosis
• To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early
• COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis
• Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis
• Voriconazole For Chronic Bronchopulmonary Aspergillosis
• Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment
• Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant
• Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043)
• MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)
• Voriconazole With or Without Interferon Gamma in Treating Patients With Aspergillosis or Other Fungal Infections
• Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis
• A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome® for Treatment of Invasive Aspergillosis (IA).
• Study of FK463 for the Treatment of Invasive Aspergillosis
• Voriconazole to Prevent Systemic Fungal Infections in Children
• A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma
• Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis
• Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
• An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections
• Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis