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Clinical Trials for Respiratory Tract Diseases

• A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC
• Study to Evaluate the AIO-001 in Healthy Participants
• RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection
• Efficacy of Probiotics (LiveSpo Navax) in Preventing Respiratory Diseases in Children
• Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
• Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Respiratory Disease
• Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)
• Povidone Iodine Nasal Application to Prevent Intraoperative Spread of SARS-CoV-2
• Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia
• Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
• A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 50-59 Years of Age, Including Adults at Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease, Compared to Older Adult
• Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease
• Study of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer With Activating EGFR or HER2 Mutations, Including Exon 20 Insertion Mutations
• A Study of Various Respiratory Syncytial Virus (RSV) Pre-Fusion (preF)-Based Vaccine Formulations in Adults Aged 60 Years and Older
• Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease
• Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
• SOLIDARITY Finland Plus Long COVID-19
• Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC
• Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)
• Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)
• Convalescent Plasma Therapy for Hospitalized Patients With COVID-19
• LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)
• NAC for Attenuation of COVID-19 Symptomatology
• Study of the Use of Nasal IFN-γ in Patients for the Prevention of Acute Respiratory Viral Infections, Icluding COVID-19
• Mechanisms of Dupilumab in AERD
• Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients
• Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2
• Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
• Interest of Nasal Provocation Tests for Diagnosis of House Mites Allergic Rhinitis
• (SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC
• PREvent Viral Exposure aNd Transmission Study: a SARS-CoV-2 PEP Study (PREVENT)
• EFFICACY and SAFETY OF BEVACIZUMAB (ZIRABEV®) IN PATIENTS WITH SEVERE HYPOXEMIC COVID-19
• Efficacy and Safety of Viusid and Asbrip in Hospitalized Patients With Mild and Moderate COVID-19
• Reconvalescent Plasma/Camostat Mesylate Early in SARS-CoV-2 Q-PCR (COVID-19) Positive High-risk Individuals
• Dupilumab in CRSsNP (Liberty CRSsNP ORION)
• Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decli
• LYT-100 in Post-acute COVID-19 Respiratory Disease
• A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
• The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19
• SILtuximab in Viral ARds (SILVAR) Study
• Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19
• Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19
• Effect of Dupilumab on Aspirin Intolerance
• Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease
• Inhaled Ibuprofen to Treat COVID-19
• Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19
• Sintilimab (IBI308) in the Neoadjuvant Treatment of Patients With Resectable II-IIIA NSCLC
• ASC Therapy for Patients With Severe Respiratory COVID-19
• Protective Role of Inhaled Steroids for Covid-19 Infection
• Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
• A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
• Daily Vitamin D for Sickle-cell Respiratory Complications
• Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients With CRS
• Apatinib Combined With SHR-1210 Injection in the Treatment of Patients With Removable IB-IIIA NSCLC
• HDDO-1801 Intervention Trial
• A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH
• Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD
• Screening for Cancer in Patients With Thromboembolic Disease
• A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcysteine (NAC) in Chinese Healthy Volunteers
• A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respirator
• The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases
• A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
• Non-specific Effects of Rabies Vaccine
• Systemic Corticosteroids Avoidance Study in Severe Asthma Patients
• A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
• Dupilumab for Aspirin-exacerbated Respiratory Disease
• Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude
• The EPIC Trial The Elderly Patient Individualized Chemotherapy Trial
• Apatinib in the Treatment of Patients With EGFR T790M-Negative NSCLC
• A Clinical Trial to Evaluate the Efficacy and Safety of YMC026 in Respiratory Disease Patients
• Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban
• A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis
• A Long Term Follow-up Study up to 4 Years After Study Vaccination to Assess Immunogenicity and Safety of the Investigational Vaccine in Adults
• A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis
• A Study of SHR-1210 in Combination With Pemetrexed and Carboplatin in Subjects With Non-squamous NSCLC
• Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Patients With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors
• Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)
• A Study to Assess the Effect of AZD5634 on Mucociliary Clearance, Safety, Tolerability and Pharmacokinetic Parameters in Patients With Cystic Fibrosis
• Intranasal Ketamine as a Sedative for Venipuncture
• A Study of Oral Hymecromone and Hyaluronan Synthesis
• What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?
• Bioequivalence of GW483100 10 Milligram (mg) Tablets in Healthy Subjects Under Fasting Conditions
• A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the Investigational GSK Biologicals' GSK3277511A Vaccine in Adults.
• The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine
• Airway Inflammation in Children With Allergic Rhinitis and Intervention
• Relative Bioavailability Study of Two Montelukast Sodium (GW483100) 5 Milligrams (mg) Chewable Tablets and One Reference Montelukast Sodium 5 mg Chewable Tablet in Healthy Adult Subjects
• Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration
• Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
• Relative Bioavailability Study of Candesartan Cilexetil Under Fasting Conditions
• Postmarketing Surveillance Study of Berotec® N 100 µg Metered-dose Inhaler in Chronic Obstructive Respiratory Tract Disease
• Postmarketing Surveillance Study of Berodual® Metered-dose Inhaler in Chronic Obstructive Respiratory Tract Disease
• Post-marketing Surveillance of Berodual® Metered-dose Inhaler in the Treatment of Chronic Obstructive Respiratory Tract Disease
• Trial to Determine the Safety of Oral Ifetroban in Patients With a History of Aspirin Exacerbated Respiratory Disease
• Recurrent Wheezing in Infants: Risk Factors and Prevention With Probiotics.
• In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation
• A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstructio
• The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases
• A Study to Investigate the Safety Tolerability Pharmacokinetics, and Pharmacodynamics of Inhaled and Intravenous GSK2862277 in Healthy Volunteers
• Efficacy and Tolerability of NM-BL in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
• Special Drug Use Investigation - Assessment of Efficacy and Safety in Treating Secondary Infection of Chronic Respiratory Disease
• A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Non-typeable Haemophilus Influenzae (NTHi) Investigational Vaccine (GSK2838497A) in Current and Former Smokers
• Therapeutic Control of Aspirin-Exacerbated Respiratory Disease (Aspirin)
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057
• Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects.
• Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
• Clinical Trial of Low Dose Oral Interferon Alpha in Idiopathic Pulmonary Fibrosis
• Special Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)
• Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)
• Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU)
• Extended Steroid in Use in Community Acquired Pneumonia (CAP)(e)
• Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis
• Prophylactic Efficacy of Relenza Against Influenza A and B
• A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease
• A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects
• Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients
• A Trial Of Azithromycin SR For The Treatment Of Acute Bronchitis And Secondary Infection Of Chronic Respiratory Diseases
• Effects Of Ciclesonide And Beclomethasone On Lens Opacification In Adult Subjects With Moderate To Severe Persistent Asthma
• Impact of Antibiotic Treatment on Outcome in Patients With Ventilator-Associated Tracheobronchitis