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Clinical Trials for Cachexia

• Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)
• Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15
• A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects
• Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.
• A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma
• A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514
• Olanzapine in Anorexia Cachexia Syndrome Among Advanced Cancer Patients
• Ruxolitinib for Cancer Cachexia
• A Phase 1 Study of AV-380 in Healthy Subjects
• Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
• Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
• MS-20 on Gut Microbiota and Risk/Severity of Cachexia in Pancreatic Cancer Patients
• The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
• Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.
• Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia
• Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency
• Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia
• A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
• A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
• Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)
• Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.
• Impact of the Use of Nandrolone on the Treatment of Malnutrition Induced by Cancer
• The Effect of Cannabis in Pancreatic Cancer
• Study of Onivyde and 5-FU in Combination With Xilonix for Pancreatic Cancer With Cachexia
• Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients
• The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers
• Safety, Tolerability, Pharmacokinetic (PK), and Pharmacodynamic Study of GSK2881078 and Study to Evaluate the Effect of CYP3A4 Inhibition on PK of GSK2881078
• A Prospective, Randomized, Controlled, Multicenter Study of Kanglaite Injection for the Treatment of Cancer Cachexia
• Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
• Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy
• Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery
• Study of Ruxolitinib in the Treatment of Cachexia in Patients With Tumor-Associated Chronic Wasting Diseases.
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of GSK2881078 in Single and Repeat Doses
• A Study to Evaluate a Skeletal-muscle Microbiopsy Technique With Dynamic Proteomic Measurement in Healthy Male Volunteers
• Effects of PINTA 745 in End Stage Renal Disease (ESRD) Patients Who Require Hemodialysis and Have Protein Energy Wasting
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2849466 in Healthy Male Subjects
• BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
• Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia
• The Role of Ghrelin in Cancer Cachexia
• Clinical Study of BYM338 for the Treatment of Unintentional Weight Loss in Patients With Cancer of the Lung or the Pancreas
• Fractional Urate Excretion in Nonedematous Hyponatremia
• Pharmacokinetics of Megace F and Megace OS Under Fasting and Fed Conditions in Healthy Male Volunteers
• Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3)
• Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting
• Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2)
• Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)
• Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum
• Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)
• A Study In Healthy Subjects Of Single Doses of PF-05230901 Injected Under The Skin
• A Clinical Study With MT-102 in Subjects With Cancer Cachexia
• Open Label Study With OHR/AVR118 in Advanced Cancer Patients With Anorexia-Cachexia
• Lenalidomide for Lean Body Mass and Muscle Strength in Inflammatory Cancer Cachexia Syndrome
• Individual Dose-escalated Bi-daily Subcutaneously (sc) Ghrelin in Cancer Cachexia: a Phase I/II Study
• Pilot Study of APD209 in Cancer Cachexia
• Testosterone for Treating Cachexia in Patients With Squamous Cell Carcinoma
• A Pilot Study of Eicosapentaenoic Acid (EPA) in Patients With Cancer Cachexia
• SUN11031 in Cachexia Associated With Chronic Obstructive Pulmonary Disease (COPD)
• Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension
• Treatment of Cancer-anorexia Using Megestrol Acetate Concentrated Suspension in Lung or Pancreatic Cancer Patients
• Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss
• Multimodal Treatment Strategy for Cancer Cachexia
• Haelan and Nutrition in Cancer Patients
• Safety and Efficacy Study of Betamarc to Treat Loss of Weight and Appetite in Non-Small Cell Lung Cancer
• Regimen for the Treatment of Cachexia in Subjects With NSCLC
• Growth Hormone in the Treatment of HIV-Associated Wasting
• Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.
• Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia
• Insulin Treatment in Cancer Cachexia
• Effects of Growth Hormone in Chronically Ill Children
• Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.
• Effects of Infliximab (Remicade) on Fat Free Mass in Patients With Moderate to Severe COPD Suffering From Cachexia
• Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss
• Pharmacokinetics and Safety of Transdermal Megestrol Acetate
• Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia
• A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
• Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer
• Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
• A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia
• Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)
• Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer
• Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite
• Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients
• Adenosine Triphosphate in Treating Patients With Advanced Solid Tumors
• Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer
• Nutrition Intervention in AIDS Wasting
• AIDS Wasting in Women: Anabolic Effects of Testosterone
• Megestrol and Exercise in Treating Patients With Cancer-Related Weight Loss
• Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting
• Phase II Randomized Study of Physiologic Testosterone Replacement in Premenopausal, HIV-Positive Women
• The Safety and Effectiveness of Megace in HIV-Infected Women
• A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition
• Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome
• A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome
• A Study Comparing Megestrol Acetate at 800 mg/Day, and Placebo in AIDS Patients With Anorexia and Cachexia
• A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss
• A Study to Evaluate High Protein Supplementation in HIV-Positive Patients With Stable Weight Loss
• A Study to Evaluate the Effect of Nandrolone Decanoate in Women With HIV-Associated Weight Loss
• A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome