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Clinical Trials for Muscle Spasticity

• Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients
• Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy
• Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
• A Phase IIb Study of Nabiximols for Spasticity Due to Neuromyelitis Optica Spectrum Disorders
• The Effect of Ultrasound-Guided Botulinum Toxin Injections on Pain, Functionality, Spasticity, and Range of Motion in Patients With Post-Stroke Upper Extremity Spasticity
• Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach
• The Effect of Botulinum Toxin and ESWT Applications on Spasticity and Functionality in Cerebral Palsy Patients
• The Effect of Dalfampridine in Hereditary Spastic Paraparezi: Randomized Controlled Trial
• Safety and Efficacy of CKDB-501A in Subjects With Post-stroke Upper Limb Spasticity
• INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT)
• Phase II Study to Assess Safety, Pharmacokinetics and Efficacy of SL-1002 for Limb Spasticity
• A Study to Investigate Arbaclofen ER Tablets for the Treatment of Spasticity in Patients With Multiple Sclerosis
• CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1)
• Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
• Testing Miglustat Administration in Subjects With Spastic Paraplegia 11
• A Study to Assess the Safety and Efficacy of IPN10200 of in Adult Participants With Upper Limb Spasticity.
• Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Patients With Multiple Sclerosis
• Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy
• Effects of Baclofen on Presynaptic Inhibition in Humans
• Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts
• Effect of Video Game-assisted and BoNT-A Injection Therapy on Spasticity, Activity and Participation in CP Patients
• Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis
• PCSK9 Inhibitor Treatment for Patients With SPG5
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity
• Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
• MEDITOXIN® Treatment in Subjects With Post-Stroke Upper Limb Spasticity
• Botulinum Toxin A & Weekly Serial Casting in ABI Inpatients With Lower Extremity Spasticity
• BX-1 in Spasticity Due to Multiple Sclerosis
• Dry Needling and Botulinum Toxin in the Management of Poststroke Spasticity
• Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study
• Effect of Botulinum Toxin Type A Associated With Physical Therapy on Children With Spastic Cerebral Palsy
• Hand Rehabilitation Using Botulinum Toxin and Functional Electrical Stimulation-pilot Study
• Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
• Dose-response Relationship of Botullinum Toxin (DWP 450) for Finger Flexor Spasticity
• Efficiency of Botulinum Toxin Injection for Spastic Equinovarus Foot in Post Stroke Hemiparetic Patients
• The Movement of Botulinum Toxin Through the Lateral Gastrocnemius Muscle in Humans: An Expanded Examination
• A Study to Evaluate the Long-term Safety of Arbaclofen Extended-Release Tablets for Patients With Spasticity Due to MS
• Peripheral Modulation of Muscle Stiffness and Spasticity
• Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings
• A Study to Investigate the Safety and Effectiveness of Arbaclofen Extended-Release Tablets for Patients With MS
• CORETOX® in Treatment of Post Stroke Upper Limb Spasticity
• A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity
• Comparing the Radial Extracorporeal Shock Waves and Botulinum Toxin Injection for Spasticity
• Effects of Botulinum Neurotoxin Type A (BoNT/A) Free of Complexing Proteins in the Spastic Equinovarus Foot
• Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC)
• Intrathecal (IT) Baclofen Drug Distribution
• Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity
• Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients
• Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 Infection
• Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Upper Extremities
• Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy?
• Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis
• The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults
• The Effects of Cannabis on Dystonia and Spasticity on Pediatric Patients
• Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Lower Extremities
• Study of the Effects on Motor Recovery of Early Post-stroke Spasticity Treatment
• Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial
• Altering Activation Patterns Post-stroke
• Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
• Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression
• Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5
• A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
• Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy
• OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity
• Rectus Femoris Tenotomy Versus Botulinum Toxin A for Stiff Knee Gait After Stroke
• Efficacy And Safety Of Dysport In The Treatment Of Upper Limb Spasticity In Children
• ASIS for Botox in Upper Limb Spasticity
• Myobloc Atrophy Study
• Study of SPARC1103 in Subjects With Spasticity
• RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke
• Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy
• A Randomized Study of Sativex on Cognitive Function and Mood: Multiple Sclerosis Patients
• A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb Spasticity
• An Adult Spasticity Registry of OnabotulinumtoxinA Treatment
• Study of a New Generation Botulinum Toxin A2NTX to Treat Spasticity After Stroke
• Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
• A Safety, Efficacy and Tolerability Study of Sativex for the Treatment of Spasticity in Children Aged 8 to 18 Years
• Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy
• Early Use of Botulinum Toxin in Spasticity Post Stroke.
• Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.
• One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity
• A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial
• Central Effects of Botulinum Toxin: Neurophysiological Study in Stroke Patients With Spastic Lower Limb
• Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
• Safety Study of SPARC1104
• Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease
• Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis
• Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
• Efficacy of 5 Weeks of Treatment With BGG492 in Patients With Spasticity Due to Multiple Sclerosis
• BOTOX® Treatment in Pediatric Lower Limb Spasticity
• BOTOX® Treatment in Pediatric Upper Limb Spasticity
• Efficacy and Safety Dose Titration Study of Botulinum Toxin Type A to Treat Spasticity in the Leg and Arm
• BOTOX® Treatment in Adult Patients With Post-Stroke Lower Limb Spasticity
• Neurophysiological Study of Sativex in Multiple Sclerosis (MS) Spasticity
• Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump
• Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases
• Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke
• Efficacy and Safety of SPARC0921 in Subjects With Spasticity
• Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle
• Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy
• Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke
• Special Drug Use Investigation for Botox® (Botulinum) Spasticity (BOTOX is a Registered Trademark of Allergan, Inc.)
• Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)
• JCP Study of Investigation of Patient Background Characteristics
• MEDITOXIN® Versus BOTOX® in the Treatment of Post-stroke Spasticity of the Upper Limb Spasticity
• Botulinum Toxin A Adult Gastrocnemius Muscle Study
• The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy
• Dysport® Pediatric Lower Limb Spasticity Follow-on Study
• Dysport® Adult Lower Limb Spasticity Follow-on Study
• Dysport® Pediatric Lower Limb Spasticity Study
• Dysport® Adult Lower Limb Spasticity Study
• Effect of Cannabinoids on Spasticity and Neuropathic Pain in Spinal Cord Injured Persons
• A Multicenter, Open-label, Single Dose Study of the Safety and Efficacy of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Focal Upper Limb Spasticity
• A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Upper Limb Spasticity
• SISTERS: Spasticity In Stroke Study - Randomized Study
• Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
• Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity
• A Study With IPX056 in Subjects With Spasticity Associated With Multiple Sclerosis
• Efficacy Study of Selective Tibial Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic Patients
• Trial Comparing Two Commercial Formulations of Botulinum Toxin Type A in the Treatment of Spasticity
• A Study of Sativex® for Relief of Spasticity in Subjects With Multiple Sclerosis.
• Evaluate the Maintenance of Effect After Long-term Treatment With Sativex® in Subjects With Symptoms of Spasticity Due to Multiple Sclerosis
• Cannabis for Spasticity in Multiple Sclerosis
• Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM)
• A Study of the Safety and Effectiveness of Sativex®, for the Relief of Symptoms of Spasticity in Subjects, From Phase B, With Multiple Sclerosis (MS)
• Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity
• MEOPA to Improve Physical Therapy Results After Multilevel Surgery
• Randomized Double Blind Cross Over Study for Nabilone in Spasticity in Spinal Cord Injury Persons
• Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity
• A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury
• MUltiple Sclerosis and Extract of Cannabis (MUSEC) Study
• Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis
• Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury
• IPX056 in Subjects With Established Spasticity Resulting From Multiple Sclerosis
• IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity
• One Year Extension Study To Protocol C2/5/TZ:MS-05
• Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
• Study Of GSK1358820 In Patients With Post-Stroke Upper Limb Spasticity
• IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Post-stroke Spasticity of the Upper Limb
• BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity
• Dutch National ITB Study in Children With Cerebral Palsy
• Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity
• Botox vs. Baclofen for Upper Limb Spasticity
• HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke
• Cannabis for Spasticity in Multiple Sclerosis
• Short-Term Effects of Medicinal Cannabis Therapy on Spasticity in Multiple Sclerosis
• Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity
• Effects on Quality of Life Following Dysport Treatment in Post-stroke Spasticity of the Arm
• Treatment of Spastic Equinovarus Foot After Stroke
• Vanderbilt University Spasticity Management Program Evaluation Plan
• Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
• Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist Muscles
• Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
• Safety Study of Botulinum Toxin Type A in Post-Upper Limb Stroke Patients With Reduced Lung Function
• Botulinum Toxin (BOTOX) for Cerebral Palsy
• Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe
• Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury