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Clinical Trials for Amyotrophic Lateral Sclerosis

• Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis
• An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease
• Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS
• Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
• Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis
• Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis
• Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS)
• Clinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS Patients
• Safety and Tolerability of RAG-17 in the Treatment of Amyotrophic Lateral Sclerosis Patients With SOD1 Gene Mutation
• Safety and Gut Microbiota Analysis of an Oral Microbiotherapy in Patients With Amyotrophic Lateral Sclerosis
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPG302 in Healthy Volunteers and ALS Participants
• Investigation of Cannabinoid 2-receptor Expression in the Brain and Spine of ALS-patients Compared to Healthy Controls With PET (18F-RoSMALS)
• A Multicenter, Open-label Extension Study to Investigate the Long-term Safety of FAB122 in Patients With Amyotrophic Lateral Sclerosis
• Effect of Salbutamol on Walking Capacity in Ambulatory ALS Patients
• HEALEY ALS Platform Trial - Regimen G DNL343
• A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as C
• A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fast
• Single & Multiple Ascending Dose Study of SAR443820 in Healthy Adult Participants
• Open Label Extension of TUDCA-ALS Study
• HEALEY ALS Platform Trial - Regimen F ABBV-CLS-7262
• Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)
• A Study Evaluating the Safety and Tolerability of QRL-201 in ALS
• Extension Study Evaluating The Safety And Tolerability of AMX0035
• AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy
• Treatment Combining Riluzole and IFB-088 in Bulbar Amyotrophic Lateral Sclerosis (TRIALS Protocol)
• A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031)
• Dazucorilant in Patients With Amyotrophic Lateral Sclerosis (DAZALS)
• A Study to Evaluate the Safety, Pharmacokinetics and Biodistribution of an Imaging Agent, 18F-OP-801 (18F Hydroxyl Dendrimer) in Patients With Amyotrophic Lateral Sclerosis (ALS) and Healthy Volunteers (HV)
• A Phase IIb, Randomized, Prospective, Double-Blind, Placebo-Controlled Study, to Evaluate Safety, Tolerability and Efficacy of PrimeC in Subjects With ALS
• Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS
• An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS
• A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers
• Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)
• Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis
• Triumeq in Amyotrophic Lateral Sclerosis
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial
• A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of FAB122 in Patients With Amyotrophic Lateral Sclerosis
• Study of Safety, Tolerability, and Biological Activity of LAM-002A in C9ORF72-Associated Amyotrophic Lateral Sclerosis
• HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose
• Tideglusib for the Treatment of Amyotrophic Lateral Sclerosis
• A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS
• 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)
• A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)
• NF-κB Inhibition in Amyotrophic Lateral Sclerosis
• Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment
• A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis
• TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle Cramps
• EMERALD TRIAL Open Label Extension Study
• A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD
• Low Dose IL-2 in the Treatment of Immune-associated ALS Syndrome
• The Treatment of Amyotrophic Lateral Sclerosis With Huollingshengji Granules
• Efficacy and Safety of Nitrazine in the Treatment of ALS
• A Phase 1 Study to Investigate the Safety and Pharmacokinetics of ABBV-CLS-7262 in Patients With Amyotrophic Lateral Sclerosis
• A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)
• A Study of Monepantel in Individuals With Motor Neurone Disease
• A Study of BIIB067 When Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation
• Clinical Trial on the Use of Cell Therapy in the Treatment of Patients With Amyotrophic Lateral Sclerosis
• Enoxacin for Amyotrophic Lateral Sclerosis (ALS)
• Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS)
• A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)
• RT001 in Amyotrophic Lateral Sclerosis
• Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS
• Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS
• iPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study
• Impact of the Combined Treatment of Liposomed Polyphenols With G04CB02 on the ALS Patients
• The Evaluation of the Effect of Mesenchymal Stem Cells on the Immune System of Patients With ALS
• HEALEY ALS Platform Trial - Regimen D Pridopidine
• MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)
• Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Exploratory Evaluation of [11C]MPC6827
• Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS)
• Open Label Study: Treatment of ALS Fatigue With PolyMVA
• Explore Neuroprotective Effect of Lipoic Acid in Amyotrophic Lateral Sclerosis
• A Compassionate Use Protocol of AMX0035 for Treatment of Patients With Amyotrophic Lateral Sclerosis (ALS)
• Evaluate PU-AD in Subjects With Amyotrophic Lateral Sclerosis
• Trial of Theracurmin for Patients With Amyotrophic Lateral Sclerosis (ALS)
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB105 in Participants With Amyotrophic Lateral Sclerosis With or Without Poly-cytosine-adenine-guanine (CAG) Expansion in the Ataxin-2 Gene
• Treatment of Intravenous Infusion Plasma in Amyotrophic Lateral Sclerosis
• HEALEY ALS Platform Trial - Regimen B Verdiperstat
• HEALEY ALS Platform Trial - Regimen A Zilucoplan
• A Safety and Biomarker Study of ALZT-OP1a in Subjects With Mild-Moderate ALS Disease
• HEALEY ALS Platform Trial - Regimen C CNM-Au8
• The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS
• Trial of Safety, Tolerability and Efficacy of Trametinib (SNR1611) in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Multiple Doses of AT-1501-A201 in Adults With ALS
• Treatment Continuation Study for Patients With ALS/MND Who Completed Study CMD-2019-001
• Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial
• HEALEY ALS Platform Trial - Master Protocol
• Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 Administered to Previously Treated Adults C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS)
• Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy
• An Efficacy and Safety Study of Ravulizumab in ALS Participants
• Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis
• Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD
• Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis
• Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS
• Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS)
• Ciprofloxacin/Celecoxib Combination in Patients With ALS
• CuATSM Compared With Placebo for Treatment of ALS/MND
• Study of Safety and of the Mechanism of BLZ945 in ALS Patients
• Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
• A Study to Evaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS)
• Effects of Oral Levosimendan on Respiratory Function in Patients With ALS: Open-Label Extension
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB100 Administered Orally to Adults With Amyotrophic Lateral Sclerosis
• Outcomes Mandate National Integration With Cannabis as Medicine for Prevention and Treatment of COVID-19
• Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis
• Impact of Nuedexta on Bulbar Physiology and Function in ALS
• Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET
• 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Amyotrophic Lateral Sclerosis (REPAIR-ALS)
• Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial
• Randomized, Double-blind, Safety and Efficacy of Recombinant Human Erythropoietin in Amyotrophic Lateral Sclerosis
• Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS
• Perampanel Single Ascending Dose Transcranial Magnetic Stimulation Biomarker Study in Amyotrophic Lateral Sclerosis
• Inhibition of Rho Kinase (ROCK) With Fasudil as Disease-modifying Treatment for ALS
• Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis
• A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV
• Treatment of FUS-Related ALS With Betamethasone - The TRANSLATE Study
• A Safety and Tolerability Study of ILB in Patients With Amyothrophic Lateral Sclerosis (ALS)
• Colchicine for Amyotrophic Lateral Sclerosis
• Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone Disease
• Riluzole Oral Soluble Film (ROSF) Swallowing Safety in Amyotrophic Lateral Sclerosis (ALS)
• A Study of IPL344 in the Treatment of ALS Patients
• To Determine the Maximum Tolerated Dose (MTD) of HK-001 in Healthy Volunteers
• A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis
• A Study to Evaluate the Safety, Tolerability and Efficacy of ILB in Patients With Amyotrophic Lateral Sclerosis
• Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Clinical Trial of Ultra-high Dose Methylcobalamin for ALS
• Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS
• A Pilot Trial of Triheptanoin for People With Amyotrophic Lateral Sclerosis (PALS)
• Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS
• Arimoclomol in Amyotropic Lateral Sclerosis
• Open Label Extension Study of AMX0035 in Patients With ALS
• Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis
• Riluzole Oral Soluble Film Safety and Tolerability in Amyotrophic Lateral Sclerosis
• The Effect of RNS60 on ALS Biomarkers
• Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis
• Safety and Tolerability of Perampanel in Amyotrophic Lateral Sclerosis Patients
• Rapamycin Treatment for ALS
• Study to Evaluate the Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Upper or Lower Extremity Muscles Most Affected in Subjects With ALS
• Study to Evaluate Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Appendicular Muscle in Adult Subjects With ALS
• Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis
• Treatment Effect of Edaravone in Patients With Amyotrophic Lateral Sclerosis (ALS)
• A Clinical Trial of Pimozide in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
• Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants
• Dual Treatment With Lithium and Valproate in ALS.
• A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.
• Open-label Clinical Trial of Lacosamide in ALS
• Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)
• A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• ALS Treatment Extension Study
• AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
• Effect of MD1003 in Amyotrophic Lateral Sclerosis
• Trial of Amivita in Amyotrophic Lateral Sclerosis
• Long-Term Evaluation of BIIB067
• Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)
• CC100: Phase 1 Multiple-Dose Safety and Tolerability in Subjects With ALS
• MIROCALS: Modifying Immune Response and OutComes in ALS
• A Clinical Trial to Evaluate the Safety and Efficacy of Fycompa in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Perampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS)
• Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis
• Delineating Swallowing Impairment and Decline in ALS
• A Study for Patients Who Completed VITALITY-ALS (CY 4031)
• Oxidative Stress and Apoptosis of Energy Metabolism by Deferiprone From the Circulating Lymphocytes
• Phase 1 Dose Escalation and PK Study of Cu(II)ATSM in ALS/MND
• Safety and Tolerability of Antiretroviral (Triumeq) in Patients With Amyotrophic Lateral Sclerosis (ALS).
• Use of Dalfampridine in Primary Lateral Sclerosis
• SSRIs vs. TCAs for Depression in ALS Patients
• Safety and Efficacy Study of NP001 in Patients With Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation
• Mexiletine in Sporadic Amyotrophic Lateral Sclerosis
• A Biomarker Study to Evaluate MN-166 (Ibudilast) in Subjects With Amyotrophic Literal Sclerosis (ALS)
• Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
• Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS)
• ALS Reversals - Lunasin Regimen
• A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis
• Acetylcholine Receptors From Human Muscles as Pharmacological Target for ALS
• An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)
• Food Supplement for the Treatment of Patients With Amyotrophic Lateral Sclerosis
• Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)
• Imaging and BioFluid Biomarkers in Amyotrophic Lateral Sclerosis
• A Pilot Study of RNS60 in Amyotrophic Lateral Sclerosis (ALS)
• Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year
• Effects of ODM-109 on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis
• A Trial of Tocilizumab in ALS Subjects
• A Registry-Based Clinical Trial of Pimozide in Patients With Neuromuscular Junction Transmission Dysfunction Due to ALS
• Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)
• Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
• HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
• F 18 T807 Tau PET Imaging in Familial Amyotrophic Lateral Sclerosis
• Microglial Activation Role In ALS (MARIA)
• A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral
• A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)
• A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS
• Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Tamoxifen Treatment in Patients With Motor Neuron Disease
• Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients
• Therapy in Amyotrophic Lateral Sclerosis (TAME)
• Immuno-modulation in Amyotrophic Lateral Sclerosis- a Phase II Study of Safety and Activity of Low Dose Interleukin-2
• A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS
• LIME Study (LFB IVIg MMN Efficacy Study)
• A Clinical Trial of Safety and Efficacy of Fasudil in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis
• Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)
• Study of Rasagiline in Patients With Amyotrophic Lateral Sclerosis
• GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)
• Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)
• Determining the Safety of L-serine in ALS
• The Effect of GCSF in the Treatment of ALS Patients
• Mexiletine for the Treatment of Muscle Cramps in ALS
• Clinical Trial Nuedexta in Subjects With ALS
• Rasagiline in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Gilenya in Amyotrophic Lateral Sclerosis (ALS)
• Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease
• Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis
• Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)
• Phase 3 Extension Study of Dexpramipexole in ALS
• Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS)
• Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
• Dexpramipexole and Cimetidine Drug Drug Interaction (DDI)
• Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)
• Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis
• Dose Titration Study to Test Safety and Effects of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Dexpramipexole SAD/MAD Study
• Dexpramipexole Renal PK Study
• Dexpramipexole Japanese PK Study
• An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis
• A Study to Evaluate the Effects of Multiple Doses of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Safety Extension Study of TRO19622 in ALS
• A Study of NP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Phase 3 Study of Dexpramipexole in ALS
• Safety and Tolerability of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis
• Safety Study of High Doses of Zinc in ALS Patients
• Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
• Trial of Safety and Efficacy of Rasagiline in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls
• Single-Ascending-Dose Safety/Tolerability of NP001 in Amyotrophic Lateral Sclerosis (ALS)
• A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)
• Safety, Tolerability, and Activity Study of ISIS SOD1Rx to Treat Familial Amyotrophic Lateral Sclerosis (ALS) Caused by SOD1 Gene Mutations
• Memantine Therapy in Amyotrophic Lateral Sclerosis
• Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS)
• Escitalopram (Lexapro) for Depression MS or ALS
• Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)
• Effect of Lithium Carbonate in Patients With Amyotrophic Lateral Sclerosis
• Combination Therapy in Amyotrophic Lateral Sclerosis (ALS)
• Efficacy and Safety of YAM80 in Amyotrophic Lateral Sclerosis (ALS)
• Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis
• Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS)
• First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis
• Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS
• Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
• Randomized Placebo-Controlled Crossover Trial With THC (Delta 9-Tetrahydrocannabinol) for the Treatment of Cramps in Amyotrophic Lateral Sclerosis (ALS)
• A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis
• A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response
• Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS)
• Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
• Talampanel for Amyotrophic Lateral Sclerosis (ALS)
• A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)
• Study of Pioglitazone in Patients With Amyotrophic Lateral Sclerosis
• Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS)
• Growth Hormone in Amyotrophic Lateral Sclerosis
• R(+)PPX High Dose Treatment of ALS
• Treating Amyotrophic Lateral Sclerosis (ALS) With R(+) Pramipexole Dihydrochloride Monohydrate at 60 mg/Day
• Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
• A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS
• CARE Canadian ALS Riluzole Evaluation
• A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
• A Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
• The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (ALS)
• Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS)
• G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response
• Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis
• Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)
• Clinical Trial Ceftriaxone in Subjects With ALS
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)
• Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)
• Influence of G-CSF and EPO on Associative Learning and Motor Skills
• A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS
• Clinical Trial of High Dose CoQ10 in ALS
• Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS)
• A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS)
• Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS]
• Phase II Study Using Thalidomide for the Treatment of ALS
• R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis
• Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis
• Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis)
• Safety Study of Botulinum Toxin Type A in Post-Upper Limb Stroke Patients With Reduced Lung Function
• Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS)
• Creatine for the Treatment of Amyotrophic Lateral Sclerosis
• Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis
• Minocycline to Treat Amyotrophic Lateral Sclerosis
• A 12-week, Multicenter, Safety and Dose-ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis
• Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial
• Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]
• Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease