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Clinical Trials for Digestive System Diseases

• A Trial to Learn if Dupilumab is Safe for and Helps Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis
• Efficacy Assessment of Chinese Herbal Medicine Tangweian Recipe Treating Participants With Diabetic Gastroenteropathy
• Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).
• A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis
• Efficacy and Safety of SOX Regimen Combined With Camrelizumab as Neoadjuvant Treatment in Locally Advanced Gastric Cancer: a Phase II, Single-arm Study
• Clinical Study Evaluating the Gastroprotective Effect of Carvedilol in Patients With Ischemic Heart Disease on Aspirin Therapy
• XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
• A First-in-human (FIH) Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
• A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
• Phase 1 Trial for Safety, Tolerability, and Immunogenicity of a Live, Attenuated, Oral Shigella/ETEC Combination Vaccine to Healthy Adults
• Preventive Effects of Low Dose Droperidol on the Postoperative Delirium in Non-cardiac Surgery of Elderly Patients
• Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
• Bioequivalence Study of Esomeprazole 20 Milligram (mg) Delayed-Release Capsules in Healthy Adult Participants
• Growth Hormone in Decompensated Liver Cirrhosis
• Anrotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients
• Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
• Indocyanine Green Clearance Test in Liver Transplantation (LivInG)
• Drug-drug Interactions and Safety Among JP-1366, Amoxicillin, and Clarithromycin in Healthy Volunteers
• A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
• Traditional Chinese Medicine Alleviates Stigma in Patients With Functional Dyspepsia
• A Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications
• The Role of Neuromodulators in Refractory Functional Dyspepsia
• The Treatment of Acute Gastrointestinal Injury Via Ultrasound-guided Erector Spinae Plane Block
• Phase 2 Study of NX9 for Delineation of Bowel Anatomy
• SGM-101 in Colorectal Brain Metastases.
• A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
• A Phase 1, Multicenter, Open-Label Study to Evaluate the Effect of Mild or Moderate Hepatic Impairment on the Multiple-Dose Pharmacokinetics of Ozanimod
• Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
• Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)
• Study on the Rule and Mechanism of Treating Functional Gastrointestinal Diseases From the Perspective of Liver and Spleen
• Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs
• Effect of Palatable Lidocaine Gel on Gag Reflex for Patients Undergoing Upper Gastrointestinal Endoscopy
• Cystic Fibrosis and Gut Dysmotility: The Effect of Polyethylene Glycol (PEG) on Intestinal Transit
• Anlotinib Hydrochloride Capsules Combined With CAPEOX in RAS and BRAF Wild-type mCRC Patients
• Study in Patients Suffering From Heartburn and Backward Flow of Stomach Liquid Into the Esophagus
• Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)
• A Study of PVP001, PVP002, and PVP003 in Healthy Adults and PVP001 and PVP002 in Adults With Celiac Disease
• A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)
• A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM)
• Gastric Gluten-Degradation Activity of PvP001
• Concomitant Versus Hybrid Regimen for H. Pylori Eradication
• A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer
• Safety and Efficacy of PBK-1701TC for Bowel Cleansing Before Colonoscopy
• Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders
• A Study on How Semaglutide Works on Early Stages of Scar Tissue in the Liver Assessed by Pictures of the Liver
• Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer
• Blood Pressure During ESD is Related With the Postoperative Bleeding
• Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection
• Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Patients With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors
• Efficacy, Safety and Tolerability of Eziclen®/Izinova® Versus Klean-prep® on Bowel Cleansing in Adolescents Undergoing Colonoscopy
• Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation
• Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis.
• Oral Resveratrol to Prevent Post-ERCP Pancreatitis
• Intranasal Ketamine as a Sedative for Venipuncture
• Investigation of the Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects With Type 2 Diabetes.
• Effect of Lactobacillus Reuteri DSM17938 in Neonates Treated With Antibiotics
• SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study
• Localized Therapeutics for the Treatment of Gastrointestinal Disorders II
• Prove of Concept Study, to Evaluate the Efficacy, Safety, and Tolerability of IBEROGAST in the Treatment of Bowel Troubles in Patients With Parkinson's Disease
• Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis
• Efficacy and Safety of Grazoprevir (+) Uprifosbuvir (+) Ruzasvir (MK-3682B) (MK-5172 + MK-3682 + MK-8408) Fixed Dose Combination in Chronic HCV Participants Failing Prior Antiviral Treatment (MK-3682-021)
• Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids
• Bioequivalence Study of Raperazole 20mg DR Tabs and PARIET® 20 mg DR Tabs Under Fed Conditions
• Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
• Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders
• Essentiale® Paste in Patients With Gastrointestinal Symptoms in Acute or Chronic Liver Diseases
• A Bioequivalence Study of Idiazole 20mg DR Tabs and PARIET® 20 mg DR Tabs After a Single Oral Dose Administration Under Fasting Conditions in Healthy Adults
• Efficacy of Open Label Placebo in Children With FGIDs
• A Randomized, Open-label, Three-arm Study of MZRW on Tolerability, Exposure and Pharmacokinetics
• Localized Therapeutics for the Treatment of Gastrointestinal Disorders
• Opioid Effects on Cognitive Function Following Colonoscopy
• Efficacy and Tolerability of Buscopan Plus in Painful Gastric or Intestinal Spasms
• Study of Autologous Tumor Lysate-pulsed D-CIK Combined With Chemotherapy for Gastric Cancer
• Adoptive Cell Therapy Plus Chemotherapy and Radiation After Surgery in Treating Patients With Colorectal Cancer
• PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers
• Change in Permeability of the Small Intestine After Treatment With Gluten
• Non-anesthesiologist Administered Propofol Sedation for Colonoscopy - a Randomized Clinical Trial
• Efficacy and Safety Study of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission
• Collaborative Cognitive Behavioral Therapy / Hypnotherapy for Treatment of Pediatric Functional Gastrointestinal Disease
• Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)
• Risk of Methicillin-resistant S.Aureus (MRSA) Infections in MRSA Carrier Under Introduction of Rapid MRSA Screening
• Effect of TU-100 in Patients With Irritable Bowel Syndrome (IBS)
• Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
• 89Zr-MMOT PET Imaging in Pancreatic and Ovarian Cancer Patients
• Sirolimus for Eosinophil-Associated Gastrointestinal Disorders
• Phase 2a Study of IW-9179 to Treat Functional Dyspepsia
• Efficacy and Tolerability of NM-BL in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
• Domperidone in Treating Patients With Gastrointestinal Disorders
• A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation
• Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams
• The Effect of Amoxicillin Versus Placebo on Gastrointestinal Motility in Children
• Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood
• Phase I Study to Investigate the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of CJ-12406 in Healthy Male Subjects
• Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics
• Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis
• Study to Examine the Effect of Ulimorelin on the Pharmacokinetics of Midazolam in Healthy Volunteers
• Evaluation of the Pharmacokinetics of Ulimorelin in Subjects With Hepatic Impairment and Healthy Subjects
• Low Dose Fat for the Prevention of Liver Disease in Babies With Gastrointestinal Disorders
• The Treatment of Periodontal Diseases
• Safety During Use of Paediatric Triple Chamber Bag Formulas
• Advanced Gastrointestinal Endoscopic Imaging
• Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)
• Validation of New Tests for Gastrointestinal (GI) Permeability
• Cholestasis Reversal: Efficacy of IV Fish Oil
• Domperidone for Relief of Gastrointestinal Disorders
• An Effectiveness and Safety Study of Chinese Herbal Medicine for Functional Constipation
• Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients
• A Phase I Study to Evaluate the Oral Absorption of Nepadutant in Infants
• A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation
• Transit Time and Bacterial Overgrowth Using SmartPill Capsule
• Study of Medication for Functional Abdominal Pain in Children
• Docetaxel, 5-Fluorouracil and Oxaliplatin in Adenocarcinoma of the Stomach or Gastroesophageal Junction Patients
• DIAMANTE - Diseases Infectious Analysis Microflora Antibiotic Effect
• Nexium Dyspepsia/AST
• Nexium Dyspepsia/AST
• Comparison of a "Step-Up" Versus a "Step-Down" Treatment Strategy for Patients With New Onset Dyspepsia in General Practice (The DIAMOND-Study)
• The Efficacy of Imipramine in Treatment of Refractory Functional Dyspepsia
• Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism
• A Study of Crofelemer to Treat Diarrhea Irritable Bowel Syndrome
• Humanized Anti-IL-2 Receptor Monoclonal Antibody in Moderate-to-severe Ulcerative Colitis
• A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease
• Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis
• Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease
• Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease
• A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2
• The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV
• A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients