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Clinical Trials for Mild Cognitive Impairment

• A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol
• Deferiprone to Delay Dementia (The 3D Study)
• Lithium As a Treatment to Prevent Impairment of Cognition in Elders
• Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI
• Nicotinamide as an Early Alzheimer's Disease Treatment
• A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease
• Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease
• Genomic Outcomes of Metformin
• Efficacy and Safety of 1612 Capsules in aMnestic Mild Cognitive Impairment
• Efficacy and Safety of Qinggongshoutao Bolus in aMnestic Mild Cognitive Impairment
• CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia
• A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)
• Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging
• Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations
• Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative Dementias
• An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)
• A Pilot of the Feasibility of Using the Iron-Chelator Deferiprone on Mild Cognitive Impairment
• Comparison of PET Amyloid Imaging in Japanese and Western Subjects
• 11C-Acetate PET/CT Imaging As a Biomarker of Amyloid-Induced Neuroinflammation
• Implications for Management of PET Amyloid Classification Technology
• Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
• Memory Improvement Through Nicotine Dosing (MIND) Study
• Dosage and Efficacy of Probucol-induced apoE to Negate Cognitive Deterioration
• Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia
• Quality Improvement and Practice Based Research in Neurology Using the EMR
• Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
• [18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
• Evaluate the Effects of Tolcapone on Cognitive and Behavioral Dysfunction in Patients With BI and NCD
• Candesartan's Effects on Alzheimer's Disease And Related Biomarkers
• A Study of LY2599666 in Healthy Participants and Participants With Mild Cognitive Impairment or Alzheimer's Disease (AD)
• Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment
• The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment
• Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment
• Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected Persons
• [18F]MK-6240 Positron Emission Tomography (PET) Tracer First-in-Human Validation Study (MK-6240-001)
• The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment
• The Effect of Nimodipine on the Postoperative Cognitive Dysfunction
• Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease
• BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)
• A Trial of Cilostazol in Patients With Mild Cognitive Impairment (COMCID)
• Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart
• Acupuncture Prevents Chemobrain in Breast Cancer Patients
• Effect of Donepezil on Cognition in Parkinson's Disease With Mild Cognitive Impairment (PD-MCI)
• Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
• A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD)
• Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study
• Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease
• Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
• Investigating the Clinical Consequences of Flutemetamol-PET-scanning
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
• Ritalin, Memory and Attention in MCI: a Behaviour-EEG Study
• Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease
• AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease
• Move for Your Mind - Pilot Trial
• Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury
• A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment
• NMDA-enhancing Agent for the Treatment of Mild Cognitive Impairment
• Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD
• The Effects of Methylphenidate on the Cognitive Function of Older People With Mild Cognitive Impairment
• Symptomatic Treatment of Vascular Cognitive Impairment
• A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzhei
• PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflammation in Cognitive Decline (NIDECO)
• CAndesartan vs LIsinopril Effects on the BRain
• Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019)
• Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly
• Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset
• Brain Aging and Treatment Response in Geriatric Depression
• Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
• Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)
• Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
• Body Temperature in Persons With Tetraplegia When Exposed to Cold
• Beta-Amyloid Imaging With [18F]NAV4694 Positron Emission Tomography (PET) in Predicting Progression to Alzheimer's Disease (AD) in Subjects With Mild Cognitive Impairment (MCI)
• Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease
• Nicotine Treatment of Cognitive Decline in Down Syndrome
• The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)
• Arterial Spin Labeling (ASL) MRI for Cognitive Decline
• Evaluation of Effects of Multiple Dose Regimens of CHF 5074 on Potential Biomarkers of Neurodegeneration in Subjects With Mild Cognitive Impairment
• DIetary Supplements, Executive funcTions and Vitamin D (DIET-D)
• Mild Cognitive Impairment in Men Following Androgen Deprivation
• Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images
• A Phase II Trial of Florbetapir (18F) Positron Emission Tomography (PET) Imaging in Japan of Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)
• Safety, Tolerability, Pharmacokinetics of EVP-0962 and Effects of EVP-0962 on Cerebral Spinal Fluid Amyloid Concentrations in Healthy Subjects and in Subjects With Mild Cognitive Impairment or Early Alzheimer's Disease
• Combination Treatment Study for Memory Impairment and Depression
• Efficacy of Pulsatile IV Insulin on Cognition and Amyloid Burden in Patients With Alzheimer's Disease
• Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase
• Study of Exelon Transdermal Patch in Amnestic Mild Cognitive Impairment Patients
• Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)
• NMDA-enhancing Agent for Treatment of Mild Cognitive Impairment and Mild Alzheimer's Disease
• Effects of Antimuscarinics on Cognition in Spinal Cord Injury
• Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120)
• Evaluation of Inter-reader Reliability Using Images From Subjects With Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI)
• Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease
• Evaluation of Web-based Training to Educate Physicians in the Methods of Interpreting Florbetapir-PET Scans
• A Study of the Safety and Tolerability of AZD5213 Effect on Sleep for Patients With Alzheimer's/Cognitive Impairment
• Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days
• Effects of Atomoxetine in Mild Cognitive Impairment
• Mild Cognitive Impairment in Parkinson's Disease
• Clinical Evaluation of Florbetapir F 18 (18F-AV-45)
• A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy
• Safety Study of HPP854 in Subjects With Mild Cognitive Impairment or a Diagnosis of Mild Alzheimer's Disease
• Minocycline in Patients With Alzheimer's Disease
• DaTSCAN Imaging in Aging and Neurodegenerative Disease
• Efficacy and Safety Study of Shenwu Capsule
• A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment
• Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP)
• 18-Month Study of Memory Effects of Curcumin
• Study of Intravenous Immunoglobulin in Amnestic Mild Cognitive Impairment
• A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease
• The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
• Phase II Study for Amyloid Binding Imaging Study of [18F]AV-45 in Patients With Mild Cognitive Impairment, Alzheimer's Disease and Healthy Volunteers
• Efficacy and Safety Study of Nimodipine to Prevent Mild Cognitive Impairment After Acute Ischemic Strokes
• Florbetaben (BAY94-9172) PET (Positron Emission Tomography) Imaging in MCI (Mild Cognitive Impairment) Patients
• Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment
• Disease-modifying Properties of Lithium in the Neurobiology of Alzheimer's Disease
• Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI
• Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)
• Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease
• Donepezil and the Risk of Falls in Seniors With Cognitive Impairment
• A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment
• MemoryXL Effects on Mild Cognitive Impairment Patients
• A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
• Observational Study of Cognitive Outcomes for Subjects Who Have Had Prior PET Amyloid Imaging With Florbetapir F 18 (18F-AV-45)
• Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
• Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers
• Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI)
• A Phase II Trial of 18F-AV-45 Positron Emission Tomography (PET) Imaging in Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)
• Metformin in Amnestic Mild Cognitive Impairment
• Effect of AQW051 in Patients With Memory Impairment
• Efficacy and Safety of Piracetam Taken for 12 Months in Subjects Suffering From Mild Cognitive Impairment (MCI)
• The Effect of Melatonin on Cognitive Function in Patients Diagnosed With Mild Cognitive Impairment
• Hormone and Information Processing Study
• An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.
• Efficacy and Safety of Ginkgo Biloba Extract in Mild Cognitive Impairment and Cerebrovascular Insufficiency
• SNIFF 120: Study of Nasal Insulin to Fight Forgetfulness (120 Days)
• Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment
• Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery
• Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment
• The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI)
• SMART: Somatotrophics, Memory, and Aging Research Trial
• Rosiglitazone Effects on Cognition for Adults in Later Life
• A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment
• A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment
• A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment
• Efficacy and Safety of S18986 in the Treatment of Mild Cognitive Impairment Patients
• Efficacy and Safety of Rivastigmine in Patients With Mild Cognitive Impairment
• Nicotine Treatment of Mild Cognitive Impairment (MCI)
• Efficacy And Safety Of CX516 In Elderly Participants With Mild Cognitive Impairment.
• Memory Impairment Study (Mild Cognitive Impairment Study)