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Clinical Trials for Pruritus

• The Effect of Omega-3 Fatty Acids Versus Gabapentin in Uremic Pruritus in Hemodialysis Patients
• Propofol for Prophylaxis of Morphine Induced Pruritis in Caesarean Section
• The Efficacy of Hemp-containing Cream Versus Placebo in the Treatment of Uremic Pruritus
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica
• Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus
• A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis
• Gabapentin Versus Loratadine in Uremic Pruritus
• Postoperative Pain After Caesarian Section
• Evaluation of the Efficacy of CANNABIDIOL on the Pruritus in Children With Hereditary Epidermolysis Bullosa
• Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis
• A Study of Thalidomide in the Treatment of Refractory Uremic Pruritus
• The MC2-25 Cream in Subjects wITh CHronic KIdNEy Disease-aSsociated prurituS (ITCHINESS) Trial
• Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1%
• KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)
• Food Effect Study of Linerixibat Tablets in Healthy Adult Participants
• Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis
• CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus and Not on Dialysis
• A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus and Not on Dialysis
• Sertraline Effect in Uremic Pruritis
• Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli
• Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
• DIalysis Symptom COntrol-Pruritus Outcome Trial
• Inhibitory Effect of Propofol on Perineal Pruritus in Patients Undergoing Day Surgery
• A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients With Chronic Kidney Disease-Associated Pruritus
• Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants
• To Evaluate the Efficacy and Safety of Nemolizumab for 12 Weeks in Participants With Chronic Kidney Disease With Associated Severe Pruritus
• Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
• Efficacy of Abrocitinib for Reducing Pruritus in Adults With Prurigo Nodularis and Chronic Pruritus of Unknown Origin
• A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus
• Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)
• Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis
• Treatment of Pruritus With Intramuscular Promethazine
• A Multi-site Bridging Study of Nalfurafine Hydrochloride Orally Disintegrating Tablet
• A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)
• A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis
• PHOTOTHERAPY VERSUS PREGABALIN IN TREATMENT OF REFRACTORY UREAMIC PRURITIS
• The Treatment Effect of Chinese Medicine Formula on Uremic Pruritus
• AST-120 in Hemodialysis Patients With Uremic Pruritus
• Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.
• Adding Nalbuphine for Control of Intrathecal Morphine Pruritus
• Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.S
• Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus
• A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of HSK21542 Injection in Subjects Undergoing Hemodialysis
• A Pharmacokinetics and Safety Study of Narfurine Hydrochloride Orally Disintegrating Tablets
• Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
• Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
• Study to Investigate the Safety of LT5001 Drug Product for Uremic Pruritus in Hemodialysis Patients
• The Effect of Propofol on Dexamethasone-induced Perineal Pruritus
• The Effect of Midazolam on Dexamethasone-induced Perineal Pruritus
• Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone
• A Study of SHR0410 in Hemodialysis Patients With Pruritus
• Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus
• Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence
• Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexone
• A Study of SHR4010 in Patients With Hemodialysis
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis
• CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
• Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects
• Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus
• Assessment of Suppression of Cutaneous Allergic Responses and Pruritus by Topical Doxycycline
• A Study to Assess the Efficacy, Safety and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases
• A Trial of SHR0410 Injection in Hemodialysis Participants.
• Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin
• A Neurokinin-1 Receptor Antagonist for the Treatment of Pruritus in Patients With Epidermolysis Bullosa
• Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis
• Aprepitant Versus Hydroxyzine in Persistent Aquagenic Pruritus for Patients With Myeloproliferative Neoplasms
• A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.
• Study to Evaluate ASN008 Topical Gel (TG)
• Comparison of Gabapentin With Doxepin in the Management of Uremic Pruritus
• RDD1609 as a Treatment for Idiopathic Pruritus Ani
• Treatment of Chronic Itch in Patients Under Arsenic Exposure With Sublingual Naloxone
• Treatment of Nighttime Pruritus in Atopic Dermatitis
• Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis
• CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
• A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus
• Safety and Efficacy of PG102P for Uremic Pruritus in HD Patients
• Apremilast Treatment for Pruritus and Quality of Life in Scalp Psoriasis
• Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis
• Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)
• PRISM Study-Pruritus Relief Through Itch Scratch Modulation
• A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis
• Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene
• A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)
• Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis
• Safety, Efficacy, and Tolerability of SNA-120 in Subjects With Pruritus Associated With Psoriasis Vulgaris
• Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneus
• Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
• Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?
• A Study Examining the Medication Apremilast as Treatment for Chronic Itch
• A Study of SK-1405 in Hemodialysis Patients With Uremic Pruritus
• Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section
• Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
• Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine
• Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration
• TRK-820 Study in Subjects on Hemodialysis With or Without Uremic Pruritus
• Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury
• Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis
• Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis
• Effect of Slow Injection of Fentanyl on the Incidence of Spinal Anesthesia Induced Itching in Cesarean Section
• Relieving Chronic Itch: Oral Medication
• Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
• A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405
• Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL
• Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section
• Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch
• Treatment of Uremic Pruritus With PA101B
• Trial to Determine the Therapeutic Benefit of an OTC Cream on Dry, Itchy Skin of Adults and Children With Eczema
• Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus
• Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients
• Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis
• A Study to Investigate the Receptor Occupancy of SK-1405 in Healthy, Caucasian, Male Subjects
• Aprepitant vs. Desloratadine in EGFR-TKIs Related Pruritus Treatment
• Itch Relieving Effect of Botox: a Study in Healthy Subjects
• A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Skin Pruritus
• Montelukast for Treatment of Uremic Pruritus
• Safety, Pharmacokinetics and Preliminary Efficacy of Asimadoline in Pruritus Associated With Atopic Dermatitis
• Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
• IBAT Inhibitor A4250 for Cholestatic Pruritus
• Comparison of Epidural Oxycodone and Epidural Morphine
• Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy
• Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus
• Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis
• Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus
• Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
• Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome
• Evaluation of the Antipruritic Effect of PAC-14028 Cream in Skin Pruritus
• Efficacy of Calmmax Cream in the Management of Chronic Uremic Pruritus
• Evaluating the Effect of Senna in Uremic Pruritus
• Proof of Concept of VLY-686 in Subjects With Treatment-Resistant Pruritus Associated With Atopic Dermatitis
• Intrathecal Morphine for Inguinal Hernia Repair.
• Topical Aprepitant in Prurigo Patients
• Prevention of Intrathecal Morphine Induced Pruritus: Comparison of Ondansetron and Palonosetron
• VPD-737 for Treatment of Chronic Pruritus
• Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P
• Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Eczema/Dermatitis and Dermal Pruritus (MK-4117-202)
• Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus
• PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg
• Pregabalin for the Treatment of Uremic Pruritus
• Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching
• Aprepitant in the Management of Biological Therapies-related Severe Pruritus
• Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis
• Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome
• Study to Assess the Clinical Activity of a Sequential Dose of REGN846 on Refractory Pruritus in Patients With Atopic Dermatitis
• Safety Study of Levocetirizine and Fexofenadine
• Efficacy and Safety Study of TRK-820 to Treat Conventional-treatment-resistant Pruritus in Patients Receiving Hemodialysis
• Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
• A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
• Gabapentin for the Treatment of Pruritus Caused by Burn Injuries in Children
• Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus
• Naloxone for the Treatment of Opioid-Induced Pruritus
• Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients
• Safety and Efficacy of DNK333 in Atopic Dermatitis Patients
• Efficacy of Baby Talcum in Prevention of Pruritus Assosiated With Cast
• Dose-Finding Study of M516102 in the Treatment of Pruritus Associated With Atopic Dermatitis
• Study of TS-022 in Adult Patients With Atopic Dermatitis With Pruritus (POC)
• Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section
• Management of Pruritus With Xyzal in Atopic Dermatitis
• Phase IIa Safety and Efficacy Study of SRD174 Cream in Patients With AD-associated Pruritus
• A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)
• Observation of Use of Claritin (Loratadine) Tablet, RediTabs, and Dry Syrup in Children (Study P05834)(COMPLETED)
• Colesevelam Versus Placebo in Cholestatic Pruritus
• Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus
• Epidural Nalbuphine for Postcesarean Epidural Morphine Induced Pruritus
• Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients
• Phase II Study of TRK-820 Soft Capsules - Intractable Pruritus in Patients With Chronic Liver Disease -
• Gabapentin - A Solution to Uremic Pruritus?
• Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents
• Nalbuphine for the Treatment of Opioid Induced Pruritus in Children
• Fexofenadine in Pruritic Skin Disease
• Study Of Cutaneous Disease Accompanied With Pruritus In Pediatrics
• Epidemiology and Control of Mansonella Perstans Infection in Uganda
• Post Burn Pruritus Study in Patients Undergoing Wound Healing
• Treatment of Cholestatic Pruritus With Sertraline
• Gabapentin to Treat Itch in Patients With Liver Disease