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Clinical Trials for Hypertriglyceridemia

• Study of MAR001 in Adults With Metabolic Dysfunction
• Study of the Efficacy and Safety of NST-1024 Versus Placebo in Subjects With Hypertriglyceridemia
• To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia
• A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamic Effects of VSA003 in Chinese Adult Healthy Volunteers
• A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)
• A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia
• A Study of LY3875383 in Healthy Participants and Participants With Hypertriglyceridemia
• A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia
• MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
• A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia
• A Study of ISIS 678354 Administered to Participants With Severe Hypertriglyceridemia
• Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis
• An Efficacy and Safety Study of Omega-3-acid Ethyl Ester in Chinese Subjects With Hypertriglyceridemia.
• Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia
• Efficacy and Safety of EzetimiBe/Rosuvastatin in Diabetic Dislipidemia With Hypertriglyceridaemia
• Safety and Efficacy of MAT9001(Omega-3-pentaenoic Acid) in Subjects With Triglycerides ≥500 mg/dL and <2000 mg/dL
• A Phase 1, First Time in Humans Study of NST-1024
• Study to Explore the Efficacy and Safety of BIO89-100 in Subjects With Severe Hypertriglyceridemia
• Investigation Of Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Single Doses Of Vupanorsen In Japanese Healthy Adult Participants With Elevated Triglycerides
• A First in Human Study of STT-5058, an Antibody That Binds ApoC3
• TRIgyceride And Glucose Control With Epeleuton in Metabolic Syndrome Patients
• Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia
• Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia
• Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia
• Vascepa to Accelerate Lipoprotein Uptake and Elimination
• Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)
• Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients
• Efficacy of MND-2119 in Participants With Hypertriglyceridemia
• Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia
• Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment
• Study of Gemcabene in Adults With FPLD
• Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis.
• Safety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute Pancreatitis
• Phase I Drug-drug Interaction of Omega-3 and Atorvastatin
• A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)
• Study of ISIS 678354 (AKCEA-APOCIII-LRx) in Participants With Hypertriglyceridemia and Established Cardiovascular Disease (CVD)
• Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease
• A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2)
• Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis
• Setmelanotide in a Single Patient With Partial Lipodystrophy
• The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN)
• Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment
• Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function
• A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia
• Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy
• Safety, Tolerability, PK, and Pharmacodynamics(PD) of IONIS APOCIII-LRx in Healthy Volunteers With Elevated Triglycerides
• Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®)
• Orlistat for the Treatment of Type I Hyperlipoproteinemia
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia
• Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects
• Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides
• Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides
• Pentoxifylline Treatment in Acute Pancreatitis (AP)
• AZD0585 Phase III Long-term Study in Japan
• A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects.
• A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules
• Efficacy and Safety of Prescription Omega-3 Fatty Acid Added to Stable Statin Therapy in Patients With Type 2 Diabetes and Hypertriglyceridemia
• The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia
• Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia
• An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis
• PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA
• Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia
• Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia
• Apolipoprotein CIII Reduction Via Colchicine
• Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome
• Epanova® for Lowering Very High Triglycerides II (EVOLVE II)
• A Pilot Study to Evaluate the Lipid Effects of TRIA-662
• Effect of DHA on Lipid and Carbohydrate Metabolism Alterations and Body Fat Distribution in HIV Patients Under HAART.
• The Efficacy of EPA+DHA (SC401B) for Lowering Triglyceride Levels (≥ 500 mg/dL)
• Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
• Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia
• Study to Assess the Safety and Tolerability of Single Doses of REGN1500
• An Efficacy and Safety Study of Omacor® in Taiwanese Hypertriglyceridemic Patients
• Vascular and Metabolic Effects of Fenofibrate/Omega vs Fenofibrate
• Vascular and Metabolic Effects of Omega-3 Fatty Acids
• Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome
• A Pilot Study to Assess the Efficacy and Safety of LCQ908 Alone and in Combination With Fenofibrate or Lovaza® in Patients With Severe Hypertriglyceridemia
• Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils
• A Clinical Trial to Evaluate the Safety and Efficacy of ZYH7 Compared to Fenofibrate in Patients With Dyslipidemia
• Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia
• Effects of DPP-4 Inhibition on Triglycerides
• Assess the Safety and Efficacy of NKPL66 (CaPre™) in the Treatment of Mild-to-high Hypertriglyceridemia
• A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High Risk Patients With Hypertriglyceridemia and on Statin. The Primary Objective is to Evaluate the Effect of 4 g/Day AMR101 for Preventing the Occurrence of a First Major
• Effects of Acipimox on Mitochondrial Function in Obesity
• The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects
• Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia
• Efficacy of LCQ908 on Cardiovascular Risk
• Chinese Medicine Treatment of Obesity With Type 2 Diabetes, Dyslipidemia
• A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic
• TRIal For Efficacy of Capre on hyperTriglyceridemiA
• Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals
• [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROL
• Long-term Efficacy and Safety Study of TAK-085 in Participants With Hypertriglyceridemia
• Efficacy of TAK-085 in Participants With Hypertriglyceridemia
• A Study to Assess the Efficacy and Safety of ETC-1002 in Subjects With Elevated Blood Cholesterol and Either Normal or Elevated Triglycerides
• Pioglitazone Attenuates Dysmetabolism in Peritoneal Dialysis (PD) Patients
• Epanova® for Lowering Very High Triglycerides
• Efficacy Study to Treat Subjects With Severe Hypertriglyceridemia
• Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia
• Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, Evaluation
• Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia
• The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers
• Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia
• Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I)
• Comparison of Fenofibrate and Niacin in Patients With Hypertriglyceridemia and Low High-Density Lipoprotein (HDL)-Cholesterol
• Intravenous Fat Emulsions and Premature Infants
• Effects of Omega-3 Fatty Acids on Platelets in Patients With Coronary Artery Disease With Hypertriglyceridemia
• Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL
• Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)
• The Impact of Omega Three Fatty Acids on Vascular Function in HIV
• Effects of Prescription Omega-3 Acids on Glucose and Lipoprotein Lipids in Subjects With Hypertriglyceridemia
• Predictors of Response to Fenofibrate
• Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects
• Differential Metabolic Effects of Fenofibrate and Fatty Acid
• Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides
• Effects of Lovaza on Lipoprotein Composition and Function in Mild Hypertriglyceridemia
• Triglyceride Lowering Study
• Lovaza® and Microvascular Function in Type 2 Diabetes
• Fish Oil Study for High Triglyceride Levels in Children
• Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects
• Open-Label, Single- and Multiple-Dose Pharmacokinetic Study of Diazoxide Choline
• A Second Open-Label Extension of a Double-Blind, Parallel, Phase IV Study to Assess the Efficacy and Safety of Adjunctive Lovaza® (Formerly Known as Omacor®) Therapy in Hypertriglyceridemic Subjects Treated With Antara™
• Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy
• Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia
• Rosiglitazone And Fenofibrate Additive Effects on Lipids (RAFAEL)
• Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and Triglycerides
• The Effects of Omega-3 Fatty Acid (OMACOR) on the Low-density Lipoprotein (LDL) Sub-fraction in Type 2 Diabetic Patients
• Effects of Fenofibrate on Adipocytokine Levels In Hypertriglyceridemic Patients
• Diazoxide Choline in Hypertriglyceridemia
• Effect of Omega-3 Fatty Acid Supplementation on Hypertriglyceridemia in HIV-infected Children
• Open-label Pharmacokinetic Study of Diazoxide Choline Coated vs. Uncoated Formulations
• An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy
• Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides
• Pharmacological Regulation of Fat Transport in Metabolic Syndrome
• Effect of Omacor on Triglycerides in HIV Infected Subjects
• Evaluation of Safety and Effects of SLx-4090 After Dosing for 14 Days in Subjects With High Triglycerides
• Regulation of Inflammatory Parameters by Telmisartan in Hypertensive Patients
• Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated Triglycerides
• Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients
• Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism
• Evaluation of Efficacy and Safety of Omacor, Co-Administered With Atorvastatin, in Subjects With Hypertriglyceridemia
• Effects of Micronized Fenofibrate on Fasting and Postprandial Lipoproteins, Inflammatory Mediators and Thrombosis
• Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients
• The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes
• Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients
• Niacin, N-3 Fatty Acids and Insulin Resistance
• Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic
• Evaluation of Efficacy and Safety of Combined Omacor (Omega-3-acid Ethyl Esters) and Simvastatin Therapy in Hypertriglyceridemic Subjects
• Evaluation of Efficacy and Safety of Omacor (Omega-3-acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate) Followed by an 8-week Extension
• Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV
• Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia
• A Study on Efficacy and Safety of Topiramate in Treatment of Obese Subjects With Dyslipidemia
• Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
• A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides
• Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy
• Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides
• A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)
• Study of Ezetimibe and Fenofibrate in Patients With Mixed Hyperlipidemia (0653-036)(COMPLETED)
• Two Investigational Drugs in Patients With Mixed Hyperlipidemia (0653-036)
• Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy
• The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART)
• Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
• Garlic in Hyperlipidemia Caused by HAART
• Rosiglitazone and Exercise Training: Effects on HIV-Infected People With Insulin Resistance, Hypertriglyceridemia, and Adipose Tissue Maldistribution