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Clinical Trials for Sleep Wake Disorders

• Sleep and Neuropathic Pain - Intervention Study on Pregabalin
• the Effects of Different Therapy Regimens on Menopausal Sleep Disorders
• Feasibility Study on the Use of Redormin®500 on Day-time Cognition
• Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children
• Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
• Effect of Propofol on Postoperative Sleep Quality in Elderly Patients With Sleep Disorders
• The CANabidiol Use for RElief of Short Term Insomnia
• The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)
• Sleep Disorders in Chronic Kidney Disease Patients
• Cannabinoids as a Treatment for Insomnia in Major Depression
• OpicApone Sleep dISorder
• Do Endotypes Predict Response and Sequelae in OSA Patients
• Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
• Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia
• Fremanezumab, Migraine and Sleep
• Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)
• Yangzheng Compound Mixture in the Treatment of Sleep Disorder in Cancer Patients
• Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder
• Opioid-Free Anesthetic for Tonsillectomy
• Effectiveness of Bryophyllum in Nocturia-Therapy
• An Open Label Study of FT218 in Subjects With Narcolepsy
• Melatonin in ADHD and Sleep Problems
• Study to Evaluate the Efficacy and Safety of Tegoprazan in ERD Patients With Nighttime Heartburn and Sleep Disturbance
• Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
• Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder
• Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment
• the Efficacy and Safety of Agomelatine in the Patients With Parkinson's Disease
• Cannabis For Cancer-Related Symptoms
• Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence
• Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes
• Medical Management of Sleep Disturbance During Opioid Tapering
• The Efficacy of Melatonin in the Burning Mouth Syndrome
• The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder
• Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
• Efficacy of Fluoroscopic Guided Atlantoaxial Joint Injection on Head and Neck Pain and Sleep Quality in RA Patients
• Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans
• Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient
• Study to Evaluate Improvements of the Quality of Sleep With NOVANUIT® Triple Action in Healthy Volunteers With Sleep Disorders
• Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm
• The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial
• A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
• AT1R Blockade and Periodic Breathing During Sleep in Hypoxia
• Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients
• Perioperative Lignocaine and Sleep Disturbance
• Improving Sleep Quality in Heart Failure
• Lavender Aromatherapy on Sleep Quality and Metabolic Parameters of Type 2 Diabetic Patients With Insomnia
• Multimodal Sleep Pathway for Shoulder Arthroplasty
• Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease
• Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
• Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation
• Functional Assessment of Ashwagandaha Root Extract During Weight Loss
• Z-Drugs for Sleep Disorders in Alzheimer's Disease
• Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain
• Effect of Continuous Apomorphine During the Night on Sleep Disorders in Insomniac Patients With Parkinson's Disease
• Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia
• Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
• Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease
• Treatment of Sleep Disturbances in Trauma-affected Refugees
• Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders
• Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders
• Risk and Benefit Assessment of Hypnotic Agents for Sleep Disorders Among Elderly
• Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
• The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia
• Atripla to Stribild Switch Study to Evaluate Sleep Disturbances
• Clock and Narcolepsy Genetic Variants and the Effects of Stalevo® (Levodopa/Carbidopa/Entacapone) on Sleep Disorders in Parkinson's Disease
• The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome
• Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances
• Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift
• The Ability of Songha Night ® to Improve Sleep in Patients With Mild to Moderate Sleep Disturbances
• Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease
• Open Label Study to Assess the Absolute Bioavailability of Tasimelteon (HETLIOZ™)
• Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers
• Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia
• Does Melatonin Restore Sleep Architecture in Autistic Children
• Study of Brexpiprazole as Adjunctive Treatment of Sleep Disturbances in Patients With Major Depressive Disorder
• Different Doses of Oral Melatonin Supplements in Chronic Kidney Disease (CKD)-Associated Sleep Disorders
• Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients
• Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance
• Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities
• Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
• Mirtazapine for Sleep Disorders in Alzheimer's Disease
• The Nuvigil and Provigil Pregnancy Registry
• Iron Treatment of Sleep Disorders in Children With Autism Spectrum Disorder
• Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer
• Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement
• Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High Altitude
• A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food
• Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction
• Effects of Rasagiline on Sleep Disturbances in Parkinson's Disease
• Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder
• Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception
• Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension
• The Effect of Melatonin on Depression, Anxiety, Cognitive Function and Sleep Disturbances in Breast Cancer Patients
• Providing "Good Sleep" for ICU Sedation
• Sleep Disruption in New Mothers: An Intervention Trial
• A Single-centre Open Label Study to Investigate the Effect of Repeat Doses of SB-649868 on the Pharmacokinetics of Simvastatin and Atorvastatin in Healthy Male Volunteers.
• Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32
• The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
• Safety Study of Tasimelteon for Treatment of Non-24-Hour-Sleep-Wake Disorder in Blind Individuals With No Light Perception
• Multidimensional Measurement of Psychopharmacological Treatment Response
• Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder
• Effect of Guanfacine Extended-Release on Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia
• Trazodone for Sleep Disorders in Alzheimer's Disease
• Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ABT-652 in Subjects With Excessive Daytime Sleepiness
• Sleep Satisfaction and Psychomotor Performance of Adults
• Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy
• Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum Disorders
• Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers
• Efficacy and Safety Assessment of ZOlpidem (Stilnox CR) in Patients With Chronic insomNIA
• Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
• Vestipitant 28-day Tolerance Study
• Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
• Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects
• Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
• Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor
• Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain
• Melatonin for Circadian Sleep Disorders in the Blind
• Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon
• Effects of Daytime Eszopiclone Administration in Shift Workers
• Effects Of Pregabalin (Lyrica) On Sleep Maintenance In Subjects With Fibromyalgia
• Study of Sleep-maintenance Activity of 3 Doses of SKP-1041
• Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
• Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders
• Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome
• Zolpidem CR and Hospitalized Patients With Dementia
• Melatonin Studies of Totally Blind Children
• Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz
• A Pilot Study to Investigate the Effect of Cytotoxic Therapy and/or Radiotherapy on Cancer Related Sleep Disturbances in CLL and Breast Cancer Patients Experiencing Fatigue
• Twenty-six Week Extension Trial of Org 50081 (Esmirtazapine) in Outpatients With Chronic Primary Insomnia (176003/P05721/MK-8265-007)
• Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Disturbance
• The Impact of Salmeterol-Fluticasone on Sleep in Patients With COPD
• Actigraphic Analysis of Treatment Response
• Melatonin for Circadian Sleep Disorders in the Blind
• Safety and Efficacy of Ramelteon in Healthy Subjects
• Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02
• Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia
• Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD)
• A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002)
• A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux
• Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome
• Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance
• Modafinil, Sleep, and Cognition in Cocaine Dependence
• Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)
• Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)
• A Long-Term Safety Study of Org 50081 (Esmirtazapine) in Elderly Outpatients With Chronic Primary Insomnia (176005/P05697/MK-8265-001)
• Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
• Insomnia and Daytime Function in Osteoarthritis
• Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
• Acute and Residual Effects of Caffeinated Beer
• Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia
• Treatment Strategies for Children With Smith-Magenis Syndrome
• Single Dose Pharmacokinetic and Pharmacodynamic Evaluation of Three Different Doses of Zolpidem in Children
• Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers
• Ramelteon (ROZEREM) in the Treatment of Sleep Disturbances Associated With Parkinson's Disease
• The Efficacy of Melatonin in Sleep Problems of Hemodialysis and Peritoneal Dialysis Patients
• Melatonin and Quality of Life in Dialysis Patients
• Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders
• Effect of Eszopiclone on Sleep Disturbance and Pain in Cancer
• The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726)
• Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
• A Phase IV Trial With Pramipexole to Investigate the Effects on RLS Symptoms and Sleep Disturbance in Patients With RLS
• Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia
• Sleep Disorders and Gastroesophageal Reflux Disease (GERD)
• A Double-blind, Group-comparison Study Using Zolpidem (Myslee) as a Comparative Drug in Patients With Insomnia
• Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees
• Study Evaluating DVS-233 SR to Treat Vasomotor Systems Associated With Menopause
• A Trial to Compare the Efficacy of Rotigotine Transdermal Patch to That of Ropinirole on Early Morning Motor Impairment and Sleep Disorders in Subjects With Early-Stage, Idiopathic Parkinson's Disease
• A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson's Disease
• Melatonin Supplements for Improving Sleep in Individuals With Hypertension
• Study of the Efficacy and Multiple-Dose Plasma Concentration-Time Profiles of Armodafinil and PROVIGIL
• Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
• Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance
• Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome
• Study Evaluating Totelle® in Menopausal Symptoms and Sexual Function
• Characteristics of Sleep Patterns in Young Adults With and Without Insomnia
• Provigil (Modafinil) Study by Taiwan Biotech Co.
• Impact of Smoking Cessation on Sleep - 5
• Effects of Vitamin B12 on the Body's Internal Clock
• Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder
• Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
• Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer
• Safety/Efficacy Study With Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Chronic SWSD
• Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder
• Trazodone for Sleep Disturbance in Early Alcohol Recovery
• Growth Hormone Releasing Hormone (GHRH) Treatment for Age-Related Sleep Disturbances