Search by Medical Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Clinical Trials for Depressive Disorder, Treatment-Resistant

• Psilocybin rTMS for Treatment Resistant Depression
• BPL-003 Efficacy and Safety in Treatment Resistant Depression
• Synaptic Imaging and Network Activity in Treatment Resistant Depression
• Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders
• Glutamate Emotion Memory Study
• A Trial of GH001 in Patients With Treatment-resistant Depression
• Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
• Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
• N2O for Acute Suicidality and Depression in the ED
• Does Psilocybin Require Psychedelic Effects to Treat Depression?
• An Open-Label, Single Dose Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression
• OSU6162 as add-on in SSRI/SNRI-resistant Depression
• Clinical Predictors of Intravenous Ketamine Response in Treatment-Resistant Depression
• Efficacy, Safety, and Tolerability of a Single Administration of COMP360 in Participants With TRD
• Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression
• RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)
• Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD)
• A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD
• Psilocybin Versus Ketamine in Treatment-Resistant Depression
• Antidepressant Effects of Nitrous Oxide
• A Study to Assess Feasibility of Using Clinician-directed and Digital Application Supported Cognitive Behavior Therapy (CBT) in Conjunction With Esketamine in Participants With Treatment-resistant Depression
• The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
• A Study To Evaluate The Safety, Tolerability And Pharmacokinetics of HS-10345 In Treatment-Resistant Depression
• IMPase in Treatment-resistant Depression
• A Randomized, Double-Blind, Placebo-Controlled Study of Liafensine in Patients With Treatment-Resistant Depression
• Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression
• Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression
• Psilocybin for Treatment-Resistant Depression
• Sevoflurane for Treatment-Resistant Depression
• Nitrous Oxide for Late-Life Depression - PROTO-BRAIN
• A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant Inpatients
• Targeting IL-17A for Treatment-Resistant Depression
• Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine
• An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients
• Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial
• Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression
• ECT vs. Esketamine
• Reward Emotion Learning and Ketamine Study
• Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray
• Antidepressant Effects of TS-161 in Treatment-Resistant Depression
• The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression
• Cannabidiol for Treatment Resistant Depression
• Stellate Ganglion Block for Major Depressive Disorder.
• Clinical Study of GH001 in Depression
• Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) - Phase I
• Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression
• Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)
• Open-Label Safety Study of AXS-05 in Subjects With TRD
• Mechanistic Evaluation of Response in TRD (MERIT)
• A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression
• Ketamine for Older Adults Pilot
• An Expanded Access Protocol for Esketamine Treatment in Participants With Treatment Resistant Depression (TRD) Who do Not Have Other Treatment Alternatives
• Dopaminergic Dysfunction in Late-Life Depression
• An Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)
• The Safety and Efficacy of Psilocybin in Participants With Type 2 Bipolar Disorder (BP-II) Depression.
• Tianeptine for Treatment Resistant Depression
• Three Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive Disorder
• Biomarkers of Response to Ketamine in Depression: MRI and Blood Assays Before and After Open Label Intranasal Ketamine
• Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)
• Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent
• Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality
• Neurofeedback In Treatment Resistant Depression
• Open-Label Safety Study of AXS-05 in Subjects With Depression
• Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression
• Minocycline as Adjunctive Treatment for Treatment Resistant Depression
• Nitrous Oxide for Major Depressive Disorder
• Neural and Antidepressant Effects of Propofol (Phase 2)
• Investigate the Clinical Responses of Ethosuximide in Patients With Treatment-Resistant Depression.
• A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression
• Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression
• The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression
• Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression
• Evaluation of Schemes of Administration of Intravenous Ketamine in Depression
• Neural and Antidepressant Effects of Propofol
• Safety, Tolerability, PK and Efficacy of Single Doses of NV-5138 in Healthy Volunteers and Subjects With Treatment-Resistant Depression
• Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:
• PF-04995274 and Emotional Processing in Treatment Resistant Depression
• Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.
• A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
• Efficacy and Safety of TAK-653 in Treatment-Resistant Depression
• Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine
• Stepped Care aiTBS 2 Depression Study (Ghent)
• Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing Strategies
• ECT With Ketamine Anesthesia vs High Intensity Ketamine With ECT Rescue for Treatment-Resistant Depression
• Salicylic Augmentation in Depression
• A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)
• ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)
• Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD
• Lithium Versus Quetiapine in Treatment Resistant Depression
• NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
• Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD
• Optimizing Outcomes of Treatment-Resistant Depression in Older Adults
• Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients
• Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females
• A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression
• Antidepressant Effects of Ayahuasca: a Randomized Placebo Controlled Trial in Treatment Resistant Depression
• Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD)
• Augmentation of Treatment-Resistant Depression With An Analog of the Neuroactive Steroid Allopregnanolone
• The UTHealth Ketamine Project
• A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant Depression
• D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression
• Allogeneic Human Mesenchymal Stem Cells (hMSCs) Infusion in Patients With Treatment Resistant Depression
• Clinical Trial of the Use of Ketamine in Treatment Resistant Depression
• Ketamine Infusions for PTSD and Treatment-Resistant Depression
• Ketamine for Treatment Resistant Late-Life Depression
• Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
• A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression
• A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression
• Adjunct Minocyline in Treatment-resistant Depression
• A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression
• A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
• A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression
• Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression
• 5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females
• Minocycline as an Adjunct for the Treatment of Depressive Symptoms: Pilot Randomized Controlled Trial
• Buprenorphine Used With Treatment Resistant Depression in Older Adults
• Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
• Ketamine in Adolescents With Treatment-Resistant Depression
• A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression
• Action of Ketamine in Treatment-Resistant Depression
• Comparing Ketamine and Propofol Anesthesia for Electroconvulsive Therapy
• Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)
• Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression
• Interpersonal Psychotherapy for Treatment Resistant Depression
• Ketamine Plus Lithium in Treatment-Resistant Depression
• Ketamine for Treatment-resistant Depression: A Multicentric Clinical Trial in Mexican Population
• A Study of Olanzapine and Fluoxetine for Treatment-resistant Depression
• A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression
• A Study of Ketamine in Patients With Treatment-resistant Depression
• Buprenorphine for Treatment Resistant Depression
• Intranasal Ketamine in Treatment-Resistant Depression
• Risperidone vs. Olanzapine as add-on Treatment in Treatment Resistant Depression
• Efficacy, Safety and Tolerability of CX157 in Treatment Resistant Depression
• Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study
• Single IV Dose of GLYX-13 in Patients With Treatment-Resistant Depression
• Efficacy and Tolerability of Riluzole in Treatment Resistant Depression
• Treatment Resistant Depression (Pilot)
• Safety and Efficacy of EVT 101 in Treatment-Resistant Depression
• Buprenorphine for Late-Life Treatment Resistant Depression
• PET Biomarkers in Treatment Resistant Depression
• A Study in Relapse Prevention of Treatment-Resistant Depression
• Dopaminergic Effects of Adjunctive Aripiprazole on the Brain in Treatment-Resistant Depression
• A Study of RO4917523 in Patients With Treatment Resistant Depression
• Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients
• Optimization of IV Ketamine for Treatment Resistant Depression
• Ketamine Frequency Treatment for Major Depressive Disorder
• Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression
• AZD6765 for Treatment Resistant Depression
• Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression
• Lamotrigine in Treatment Resistant Depression in Adolescents
• Aripiprazole Augmentation Therapy in Treatment-resistant Depression
• Olanzapine Augmentation Therapy in Treatment-resistant Depression: a Double-blind Placebo-controlled Trial
• Venlafaxine Augmentation in Treatment Resistant Depression
• Effectiveness of Pramipexole for Treatment-Resistant Depression
• A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression
• Use of Risperidone in ECT for Treatment Resistant Depression
• Mifepristone in Refractory Depression
• Risperidone vs. Bupropion ER Augmentation of SSRIs in Treatment-Resistant Depression
• Risperidone (Risperdal) Augmentation in Depressed Partial Responders to SRI Treatment
• Optimizing the Effectiveness of Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment-Resistant Depression
• An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
• A Study of the Effectiveness and Safety of Risperidone to Augment SSRI Therapy in Patients With Treatment-resistant Depression
• The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression