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Clinical Trials for Hypertrophy

• Treatment of Hypopigmented Scars With Bimatoprost
• An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM
• A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
• A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846
• Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM
• Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy
• A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software
• A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy
• Opioid-sparing Effect of Intranasal Dexmedetomidine
• Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH
• Alveolar Ridge Preservation Using Different Bone Substitutes
• The Purpose of This Study is to Compare the Efficacy and Safety of Aficamten (CK-3773274) Compared With Metoprolol Succinate in Adults With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction
• Medical vs Surgical Treatment in OSA Among Children
• Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension
• A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy
• Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy
• A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
• A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar
• A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy
• Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children
• Lifestyle and Pharmacological Interventions in Hypertrophic Cardiomyopathy
• Comparison of Nebulized Budesonide and Intranasal Budesonide Spray in Children With Adenotonsillar Hypertrophy
• Phase IA Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia
• Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars
• Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases
• CY 6031 Study Will Evaluate the Effects of Treatment With Aficamten (CK-3773274) Over a 24-week Period on Cardiopulmonary Exercise Capacity and Health Status in Patients With Symptomatic oHCM
• Empagliflozin in Hypertrophic Cardiomyopathy
• A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM
• Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)
• Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectomy
• Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy
• Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test
• Efficacy of α-blocker or 5-ARI Withdrawal to Continued Combination Therapy on the Maintenance of LUTS in Men With BPH
• : Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
• Sacubitril/Valsartan Versus Amlodipine in Hypertension and Left Ventricular Hypertrophy.
• Comparison of Squat-to-Stand Maneuver With Amyl Nitrite, Valsalva, and Exercise Stress Echocardiography in Inducing Latent Left Ventricular Outflow Obstruction in Hypertrophic Cardiomyopathy
• Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery
• CY 6022 is an Open Label Study to Collect Long-term Safety and Tolerability Data for CK-3773274
• A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial
• Safety, Tolerability and Pharmacokinetics Study of CK-3773274
• Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery
• The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy
• Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
• Management of Post-Tonsillectomy Pain in Pediatric Patients
• Empagliflozin and Cardiac Remodelling in People Without Diabetes
• Evaluate the Safety and Efficacy of Botulax® in Subjects With Benign Masseteric Hypertrophy
• Role of Perhexiline in Hypertrophic Cardiomyopathy
• A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy
• A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy
• Efficacy and Safety of DWP450 in Subjects With Benign Masseteric Hypertrophy
• 5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy
• REDWOOD-HCM: Randomized Evaluation of Dosing With CK-3773274 in Obstructive Outflow Disease in HCM
• Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy
• Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy
• Tulobuterol Patch in Pediatric Patients Undergoing Tonsillectomy
• the Hypertrophic Scar Prevention of BMT101.
• Botulinum Toxins Intralesional Injection for Scar Pain
• Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy
• Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars
• LCZ696 in Advanced LV Hypertrophy and HFpEF
• Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy
• The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation
• Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy
• A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects
• A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM
• A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients
• Treatment of Hypertrophic Scars With Intradermal Botox
• Pain Outcomes Following Intralesional Corticosteroid Injections
• A Study to Evaluate Safety and PK Profiles of OLX10010 in Healthy Subjects
• Beta2-adrenergic Agonism and Muscle Remodelling
• Zinc Oxide Versus Petrolatum Following Skin Surgery
• Imaging Histone Deacetylase in the Heart
• The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy.
• Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
• Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER
• Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy
• MEDITOXIN® Treatment in Subject With Benign Masseteric Hypertrophy
• A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)
• Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter
• Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants
• Hypertrophic Scar Prevention by Novel Topical Gel Application
• Role of Topical Putrescine (Fibrostat) for Prevention of Hypertrophic Scars in Mammoplasty Patients
• DWP450 Treatment in Subjects With Benign Masseteric Hypertrophy
• Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study
• Nitrite in Hypertrophic Cardiomyopathy (HCM) Study
• Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
• Reduction of Left Ventricular Hypertrophy After Eplerenone Therapy
• Efficacy and Safety of Valsartan and Nebivolol/Valsartan in Hypertensive Patients With LVH
• Study to Investigate the Pharmacokinetics, Safety, and Tolerability of BMT101 in Healthy Male Volunteers
• Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
• Diffusion MRI in Heart Failure
• Does Dapagliflozin Regress Left Ventricular Hypertrophy In Patients With Type 2 Diabetes?
• A Randomized Study to Evaluate the Safety and Efficacy of Various Doses of STP705 in Subjects With Hypertrophic Scar
• Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy
• Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure
• A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction
• Mobilization of Endothelial Progenitor Cells and Aspirin
• A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH)
• Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection
• A Clinical Trial to Evaluate the Effects of Food on the Bioavailability of CKD-397 in Healthy Male Subjects
• Assessment of Efficacy of Mirabegron, a New beta3-adrenergic Receptor in the Prevention of Heart Failure
• Hypertrophic Cardiomyopathy Symptom Release by BX1514M
• Perfusion Imaging With Myocardial Contrast Echocardiography in HCM
• Mometasone Furoate and Oxymetazoline in the Treatment of Adenoid Hypertrophy
• cAMP Signaling and Muscle Adaptations
• Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle Hypertrophy
• Effects of Everolimus in Left Ventricular Hypertrophy After Conversion From Azathioprine: A Pilot Study
• Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery
• Effect Observation Study of COX-2 Inhibitor to Treat Primary Hypertrophic Osteoarthropathy
• Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure
• Saline With Alcohol in TransUrethral Resection aNd Photoselective Vaporisation of the Prostate
• FS2 Safety and Tolerability Study in Healthy Volunteers
• Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461
• Medytoxin® Treatment in Patients With Benign Masseteric Hypertrophy
• Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
• Diuretic Versus Placebo in Pulmonary Embolism
• Safety and Efficacy of Ingenol Mebutate 0.05% Gel When Used After Cryotherapy in the Hypertrophic Actinic Keratoses
• A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars
• Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
• MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease
• Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children
• A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study
• The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial
• The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
• A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery in Healthy Adults
• Botulinum Toxin Type A (BOTOX®) Treatment of Masseter Muscle Hypertrophy
• Effect of Isosorbide Mononitrate on Hypertension to Improve Left Ventricular Hypertrophy, Fibrosis and Myocardial Function
• Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study
• Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM
• Eplerenone and Aliskiren Research Targeting Hypertensive Patients With Left Ventricular Hypertrophy
• Cardiac Allograft Remodeling and Effects of Sirolimus
• Immune Response To Intranasal Influenza Vaccination
• Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars
• REmodelling in Diabetic CardiOmapathy: Gender Response to PDE5i InhibiTOrs
• Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
• Ranolazine for the Treatment of Chest Pain in HCM Patients
• Trimetazidine Therapy in Hypertrophic Cardiomyopathy
• Intranasal Mometasone in Children With Obstructive Sleep Apnea Due to Adenotonsillar Hypertrophy
• Effect of Deep BLock on Intraoperative Surgical Conditions
• Intraprostatic Botulinum Toxin Type "A" Injection in Patients With Benign Prostatic Hyperplasia and Unsatisfactory Response to Medical Therapy
• A Clinical Study of Allogeneic Human Dermal Fibroblasts for Remodeling Scar Contractures
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy
• Hypertrophic Regression With N-Acetylcysteine in HCM
• Inhibition of the Renin Angiotensin System With Losartan in Patients With Hypertrophic Cardiomyopathy
• Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy
• Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
• Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
• Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
• The Effects of Intrathecal Dexmedetomidine on Spinal Anesthesia Using Diluted Low-Dose Bupivacaine for Transurethral Resection of Prostate in Elderly
• Dose Response Study of VA106483 in Males With Nocturia and Benign Prostatic Hypertrophy (BPH)
• Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy
• Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan
• Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement
• A-botulinic Toxin for Symptomatic Benign Prostate Hypertrophy
• CLCNKA (Ka Renal Chloride Channel[ClC-Ka]) Polymorphism Effects on Hypertrophy Regression
• Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study
• Intravenous Enhancin[Co-amoxiclav] Versus Postoperative Enhancin in Prevention of Postadenotonsillectomy Morbidity.
• Safety and Efficacy of QD Versus BID Silodosin With Lower Urinary Tract Symptoms Suggestive of BPH
• Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses
• Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement
• Effects of Levosimendan in Patients Eligible for Aortic Valve Replacement With Left Ventricular Hypertrophy
• ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling
• Stenting of Renal Artery Stenosis in Coronary Artery Disease Study
• Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy
• Glutamate and Diastolic Function in Patients Undergoing Aortic Valve Repair
• Scars After Central Venous Catheters
• Nasonex (Mometasone Furoate Nasal Spray) in Adenoids Hypertrophy in Children (P04367)
• Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery
• Myocardial Protection With Perhexiline in Left Ventricular Hypertrophy
• Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis
• Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy
• Effect of Dutasteride on Bladder Wall Hypertrophy in Patients With Benign Prostatic Obstruction
• Antiarrhythmic Therapy Versus Catheter Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy
• Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis
• Solifenacin as Add-on Therapy for Overactive Bladder Symptoms in Men Treated for Benign Prostatic Hyperplasia
• A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars
• Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)
• MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer
• Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
• Do Xanthine Oxidase Inhibitors Reduce Both Left Ventricular Hypertrophy and Endothelial Dysfunction in Cardiovascular Patients With Renal Dysfunction?
• Intron A for the Treatment of Hypertrophic Scar
• Cetrorelix Pamoate IM Regimens in Patients With Symptomatic Benign Prostatic Hyperplasia (BPH)
• Cetrorelix Pamoate in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)
• The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5
• Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan
• Hypertension in Hemodialysis Patients (Aim 3)
• Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilage
• Placebo-controlled Trial With Nasonex for Nasal Obstruction Secondary to Adenoids Hypertrophy in Children (P04367)(TERMINATED)
• Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant
• Efficacy and Safety of Mometasone Furoate Nasal Spray in Children With Adenoid Hypertrophy. SNORE Study (P05155)
• Multicenter Prospective Study on the Changes of Sexual Function Following Treatment With Alfuzosin (Xatral XL®) in Patients With Benign Prostate Hypertrophy
• Pathophysiological Mechanisms of Hypertensive LVH:Optimising Regression
• Perhexiline Therapy in Patients With Hypertrophic Cardiomyopathy
• The PRIMO Study: Paricalcitol Capsules Benefits Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease Stage 3/4
• 5-Alpha Reductase and Anabolic Effects of Testosterone
• Vardenafil in Greenlight(TM) Laser Surgery of Benign Prostate Hypertrophy
• Cetrorelix (CET) Pamoate Regimens in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)
• Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy
• CHANCE - Candesartan in Hypertrophic Cardiomyopathy
• The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate
• Dutasteride After Failure of Finasteride In the Management of Symptomatic Prostatic Enlargement/Hypertrophy (BPE/H)
• A Safety and Efficacy Study for Epoetin Alfa in Pre-dialysis Subjects.
• I SELECT - Irbesartan In Hypertensive Patients With Left Ventricular Hypertrophy
• Candesartan Effectiveness Study in Pro-B Type Natriuretic Peptides (BNP)
• Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study (0954-133)
• Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem
• Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart
• Effect of Angiotensin II Receptor Blockers (ARB) on Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis
• Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)
• Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension
• Active Vitamin D Effect on Left Ventricular Hypertrophy
• Effects of Amlodipine/Benazepril in Reducing Left Ventricular Hypertrophy in Patients With High Risk Hypertension
• The CLEVER Study - Coreg And Left Ventricular Mass Regression
• Study of Oral PG-116800 Following a Heart Attack
• The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling
• Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate)
• Clinical Trial in Males With BPH (Enlarged Prostate)
• Medical Therapy of Prostatic Symptoms
• Pirfenidone to Treat Hypertrophic Cardiomyopathy
• Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)
• Long Term Effects of Enalapril and Losartan on Genetic Heart Disease