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Clinical Trials for Aggression

• Effect of Nitrous Oxide on Aggression.
• Relmacabtagene Autoleucel as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL
• Pimavanserin and Aggression and Social Cognition.
• Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging
• Safety Evaluation Study for Patients With Aggressive NK-cell Leukemia
• Intravitreal Ranibizumab Injection for Aggressive Versus Type 1 Prethreshold Retinopathy of Prematurity
• Study to Assess the Safety and Tolerability of REGN5837 in Combination With Odronextamab in Patients With Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma
• A Study of PR2527 in Participants With Relapsed/Refractory Hematologic Malignancies
• Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
• Antimicrobial Photodynamic Therapy in Treatment of Aggressive Periodontitis (Stage III, Grade C Periodontitis)
• A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies
• Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas
• A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas
• Mosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Autologous Stem Cell Transplant-Eligible Patients With Relapsed/Refractory Aggressive B Cell Lymphoma
• Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma
• Dialectical Behavioral Therapy Skills for Impulsive Aggression
• Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities
• CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed Aggressive Non-Hodgkin's Lymphoma (NHL).
• MK-8189 Safety and Tolerability in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis (MK-8189-017)
• Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab
• Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma
• ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma
• (Apex) CGT9486 in Patients With Advanced Systemic Mastocytosis
• A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer
• Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer
• Decitabine-primed Tandem CD19/CD20 CAR T Cells Plus Epigenetic Agents in Aggressive r/r B-NHL With Huge Tumor Burden
• Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
• DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers
• Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors
• Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Untreated Aggressive Large B-cell Lymphoma
• Vorinostat and Combination Chemotherapy Before Donor Stem Cell Transplantation for the Treatment of Relapsed Aggressive B-cell or T-cell Non-Hodgkin Lymphoma
• R2 and Combination Chemotherapy Versus R and Combination Chemotherapy in Newly Diagnosed Highly Aggressive B-NHL
• ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy
• Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome
• Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis.
• Propranolol for Challenging Behaviors in Autism
• Amoxicillin and Metronidazole in Association With Non-surgical Therapy in Aggressive Periodontitis Treatment
• Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
• Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma
• Doxycycline in the Treatment of Aggressive Periodontitis
• TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting
• Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD
• Treatment of Impulsive Aggression (IA) in Adolescent With ADHD in Conjunction With Standard ADHD Treatment
• Trial to Determine the Efficacy and Safety of JCAR017 in Adult Subjects With Aggressive B-Cell Non-Hodgkin Lymphoma
• Study of Pixantrone in CD20+ Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma
• Rapid Agitation Control With Ketamine in the Emergency Department
• uPAR-PET/MRI in Patients With Prostate Cancer for Evaluation of Tumor Aggressiveness
• Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC
• Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell Lymphomas
• Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy
• Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
• A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease
• Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Patients With Traumatic Brain Injury
• Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis
• Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis
• Oxytocin, Alcohol Craving, and Intimate Partner Aggression
• A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
• Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas
• Study to Examine the Safety and Efficacy of Pimavanserin for the Treatment of Agitation and Aggression in Alzheimer's Disease (SERENE)
• Neurokinin (NK) 1 Antagonist for Pathological Aggression for Harmful, Impulsive, and Self-/Aggressive Behaviour
• Therapy of Non-Hodgkin-Lymphoma by Combination of Lenalidomide + Rituximab, Dexa, High-dose ARA-C and CisP
• Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis
• Study to Evaluate Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory (R/R) Aggressive B-Cell NHL
• Study of Volasertib and Belinostat in Patients With Relapsed and Refractory Aggressive B-cell and T-cell Lymphomas
• Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment
• Clarithromycin as Adjuvant to Periodontal Debridement
• Exploratory Study of BO-112 in Adult Patients With Aggressive Solid Tumors
• A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
• Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
• A Trial of Imatinib for Patients With Aggressive Desmoid Tumor (Aggressive Fibromatosis)
• KPT-330 Plus RICE for Relapsed/Refractory Aggressive B-Cell Lymphoma
• Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease
• Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
• Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis
• Study of Loratadine for Pegfilgrastim Induced Bone Pain in Patients With Aggressive Lymphoma
• Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas
• Alternative Antibiotic Regime in the Treatment of GAgP
• Depakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood Swings
• Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder
• A comparatiVe Study on Efficacy and Safety of Lipegfilgrastim in Comparison to Pegfilgrastim in Elderly Patients With Aggressive B Cell Non-HOdgkin Lymphomas at hIgh Risk for R-CHOP-21-inDuced Neutropenia
• Phase I Study to Assess the Absorption, Metabolism, and Excretion of [14C] Labeled SPN-810M
• The Effects of Midazolam on the Quality of Postoperative Recovery
• Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis
• Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer
• Rituximab Maintenance Therapy in Aggressive CD20 (Cluster of Differentiation Antigen 20) Positive Lymphoma and Mantle Cell Lymphoma
• Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression
• A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
• Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
• Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
• Rituximab and Bendamustine in Very Elderly Patients or Elderly Medically Non Fit Patients With Aggressive B-cell Lymphoma
• Trial of R-GemOx Regimen in Previously Untreated Elderly Patients With DLBCL.
• Phase II Evaluation of Gemcitabine- Rituximab-Oxaliplatin Combination (GROC) in Relapsed Aggressive Lymphomas
• Aggressive Cholesterol Therapy to Inhibit Vein Graft Events After CABG (ACTIVE Trial)
• Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
• OPTIMAL>60 / DR. CHOP, Improvement of Therapy of Elderly Patients With CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine
• Open-Label, Extension Study to 810P202
• A Study to Evaluate the Efficacy and Safety of SPN-810 as Adjunctive Therapy in Children With Impulsive Aggression Comorbid With Attention-Deficit/Hyperactivity Disorder (ADHD)
• Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant
• Bendamustine, Cytarabine, Etoposide and Melphalan (BeEAM) as Conditioning for Autologous Stem Cell Transplant (ASCT) in Aggressive Non Hodgkin's Lymphoma (NHL).
• A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy
• High-dose Chemotherapy and Stem Cell Transplantation for Central Nervous System (CNS) Relapse of Aggressive Lymphomas
• Study to Evaluate Imatinib in Desmoid Tumors
• Clozapine and Olanzapine Treatment of Aggression
• Study of Veltuzumab and 90Y-Epratuzumab in Relapsed/Refractory, Aggressive NHL
• Study With Palonosetron Alone in Preventing Chemotherapy-induced Nausea and Vomiting in Untreated Patients With Aggressive Non Hodgkin's Lymphomas Who Underwent Moderately Emetogenic Chemotherapy
• Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry
• High-dose Chemotherapy With Rituximab for Adults With Aggressive Large B-cell Lymphoma
• Multicenter Trial to Treat Patients With Relapsed/Refractory Aggressive Non Hodgkin Lymphoma
• Treatment for Aggression and Agitation in Patients With Alzheimer's Disease
• Treatment of Severe Childhood Aggression (The TOSCA Study)
• Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study)
• Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia
• Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study
• Memantine on Aggression and Agitation of Alzheimer's Disease (AD)
• Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability
• Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression
• Aggressive Versus Moderate Glycemic Control in Diabetic Coronary Bypass Patients
• Positron Emission Tomography Guided Therapy of Aggressive Non-Hodgkin's Lymphomas
• Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.
• A Study of Zevalin and Simultaneous Application of BEAM High-dose Chemotherapy Followed by Autologous Stem Cell Transplantation in Refractory and Relapsed Aggressive Non-Hodgkin Lymphomas
• Dose-Dense Therapy in Aggressive Lymphoma
• Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children
• Rapid Tranquillization Trial: TREC-India II
• Antipsychotic Discontinuation in Alzheimer's Disease
• Memantine for Agitation and Aggression in Severe Alzheimer's Disease
• Depocyte in the Treatment of CNS Relapse in Patients With Lymphoblastic Leucemia or Very Aggressive Lymphoma
• Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma
• Pilot Trial of Neural Correlates of Response to Treatment of PTSD-Associated Impulsive Aggression
• Risperidone Augmentation for Treatment-Resistant Aggression in ADHD
• Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order
• Open Label, Single Arm, Phase II Study Using R-COMP in Elderly Patients With Aggressive NHL.
• Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia
• Metabolic Effects of Antipsychotics in Children
• Haloperidol vs. Risperidone in the Treatment of Aggression in Psychotic Inmates
• A Phase II Study of Clofarabine in Patients With Aggressive Non-Hodgkin's Lymphoma
• Clozapine IM and Aggression in Schizophrenic Patients
• The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Adolescents With Impulsivity and Aggressive Behavior in Conduct Disorder This Study is Not Being Conducted in the United States.
• The Effect of Oxcarbazepine in the Treatment of Agitation / Aggression in Dementia (OBAD)
• Valproate Response in Aggressive Autistic Adolescents
• A Phase II Study of Paclitaxel and Topotecan With Filgrastim-SD/01 Support For Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma
• Long-Term Lithium Treatment for Aggressive Conduct Disorder