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Clinical Trials for Constipation

• Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
• Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation
• Washed Microbiota Transplantation for Chronic Constipation in Adults
• Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation
• Tenapanor for the Treatment of Pediatric Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• Evaluate the Efficacy and Safety of Goofice® (Elobixibat) in Patients With Chronic Constipation
• Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen
• Preop Laxatives in Robotic Urologic Surgery
• Congrong Runtong Oral Liquid in the Treatment of Functional Constipation (Yang-deficiency Type)
• Colonic Motor Patterns in Healthy Volunteers
• A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide
• Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation
• Elobixibat for Chronic Constipation Without Defecation Desire
• A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
• Study to Assess the Safety and Efficacy of Tenapanor for the Treatment of IBS-C
• Pyridostigmine for the Treatment of Constipation in Parkinson Disease
• Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids
• Effect of MiniGo as add-on to Oral Laxatives for Children With Constipation and Fecal Incontinence
• Home Transcutaneous Electrical Acustimulation (TEA)
• A Randomized Single-Blind Controlled Trial Comparing the Efficacy of Nitazoxanide Versus Rifaximin in Adult Patients With Irritable Bowel Syndrome Without Constipation
• Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
• Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: A RCT (PEGASIS Trail)
• Prevention of Opioid-induced Constipation in Patients With Metastatic Cancer
• Elobixibat for Chronic Constipation Without Defecation Desire
• Efficacy and Safety of Plecanatide Comparing With Placebo in the Treatment of Functional Constipation
• Lubiprostone for Functional Constipation in the Under 18 Years Patients
• Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
• Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders
• RCE With FMT in the Treatment of Childhood Constipation
• Study of Comparative Effectiveness of Prucalopride and Lubiprostone in Constipation Predominant Irritable Bowel Syndrome
• Efficacy and Safety of Bifidobacterium Quadruple Live Tablets in Patients With T2DM and Constipation
• Defecation Patterns in Constipated Patients
• Evaluation of Clinical Equivalence Between Two Linaclotide Products in the Treatment of Chronic Idiopathic Constipation
• Long-term Elobixibat for Chronic Constipation
• Misoprostol for Bloating and Distension
• A Study of Prucalopride For Functional Constipation in Children and Teenagers
• The Effects of Prucalopride in Patients With Constipation Predominant Irritable Bowel Syndrome
• Thrice Weekly Bowel Care
• A Proof of Concept Study of Pradigastat in Patients With Functional Constipation
• Treatment of Chronic Constipation in Parkinson's Disease
• Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.
• Orally Administered ENT-01 for Parkinson's Disease-Related Constipation Follow-on Safety "Roll-over" Study (Rollover)
• Efficacy and Safety of Vibrant Capsule vs. Vibrant Placebo for the Treatment of Chronic Idiopathic Constipation (CIC)
• Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery
• Post-Operative Constipation Following Total Knee Arthroplasty
• Bowel Function After Minimally Invasive Hysterectomy
• Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy
• Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
• MRI Assessment of Mode of Action of Bisacodyl, Single Dose
• MRI Assessment of Mode of Action of Bisacodyl, Multiple Doses
• Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation
• Pharmacokinetics of Neostigmine and Glycopyrrolate
• Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
• Efficacy and Safety of PEG 3350 for Treatment of Chronic Constipation
• Botanical Tincture for Symptoms of Irritable Bowel Syndrome
• Lactobacillus Plantarum IS 10560 Supplementation in Women With Functional Constipation
• The Role of Probiotics in Improving Quality of Life in Women With Functional Constipation
• Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET)
• Efficacy and Safety of SYN-010 in IBS-C
• Blood Glucose Response After Oral Intake of Lactulose in Mildly Constipated Patients With Diabetes Mellitus Type 2
• Dried Plums (Prunes) vs. Polyethylene Glycol 4000 for Treatment of Functional Constipation in Children
• Efficacy and Safety of Plecanatide in Children 6 to <18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C)
• A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• Prunes for Gastrointestinal Function After Gynecologic Surgery
• Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation
• Investigation of the Absorption, Metabolism, and Excretion and the Absolute Bioavailability of YH12852
• Trial of Probiotics for Constipation in Parkinson's Disease
• Use of MgSO4 for Pain After Bariatric Surgery
• Naloxegol and Opioid-induced Constipation
• Fecal Microbiota Transplantation for Constipation
• Comparison of Two Methods for Bowel Preparation in Patients With Constipation
• Reclassifying Constipation Using Imaging and Manometry
• Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation
• Efficacy of Dicopeg Junior in Comparison With Lactulose for the Treatment of Functional Constipation in Children Aged 6 Months to 6 Years.
• Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation
• An Efficacy and Safety Study of Plecanatide in Adolescents 12 to <18 Years of Age With Chronic Idiopathic Constipation
• Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation
• Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo
• To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation
• The Effect of Probiotics on Constipation, and Intestinal Microflora in Children With Functional Constipation
• Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation
• Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study)
• Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids
• General Clinical Study of AJG555 in Pediatric Patients With Chronic Constipation
• Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
• Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients
• Comparison of Taste and Palatability in Fiber Supplements
• Effect of a Synbiotic on Symptoms of Patients With STC
• Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)
• RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease
• A Study of the Effect of Linaclotide on Abdominal Girth in Participants With IBS-C
• A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation
• A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation
• An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults
• BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
• Naloxegol Health Outcome Post Authorisation Safety Study
• Naloxegol US PMR CV Safety.
• Naloxegol Drug Utilization PASS
• A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation
• Clinical Trial on Palliative Cancer Patients With Constipation
• Trial of Alvimopan in Major Spine Surgery
• Use of Gastrografin in the Management of Fecal Impaction in Patients With Severe Chronic Constipation
• Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation
• Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months
• Naloxegol in Cancer Opioid-Induced Constipation
• Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects
• Lubiprostone for Chronic Idiopathic Constipation Treatment
• A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C
• The Efficacy of Mutaflor(E. Coli Nissle 1917, Mutaflor®) for Chronic Constipation:Multicenter Study
• The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit
• Lubiprostone for Treatment of Chronic Idiopathic Constipation
• A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
• A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects
• Lubiprostone for the Treatment of Chronic Idiopathic Constipation
• A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
• Treating Anorectal Dysfunction in MS
• An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation
• Study of Methylnaltrexone in Opioid-Induced Constipation Patients
• Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery
• Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section
• Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
• Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Medical Treatment
• A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation
• A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)
• Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
• Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation
• A Study of the Effect of SYN-010 on Subjects With IBS-C
• Second Plecanatide Study In Irritable Bowel Syndrome With Constipation (IBS-C)
• A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C
• A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
• Effect of Mosapride on Gut Transit in Patients With Chronic Constipation or Constipated Irritable Bowel Syndrome and Healthy Subjects
• A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation
• The Efficacy of Individualised Homeopathic Treatment on Constipation
• Elobixibat Colonic Motor Function Study
• The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)
• Botulinum Toxin Injection Versus Anal Myectomy in Management of Idiopathic Constipation
• A Randomized, Open-label, Three-arm Study of MZRW on Tolerability, Exposure and Pharmacokinetics
• Phase II Study of KWA-0711 in Patients With Chronic Constipation (CC)
• Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis
• Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction
• Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
• Effect of Fecal Microbiota Transplantation in Slow Transit Constipation
• Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005)
• Trial of Linaclotide in Patients With Chronic Idiopathic Constipation
• Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation
• Phase II Dose-Finding Study of KWA-0711 in Patients With Chronic Constipation (CC)
• Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain
• Anal Dilatation for Infants and Children With Constipation
• Efficacy of Linaclotide to Senna for CIC
• Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled Trial
• Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation
• A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically
• Efficacy and Tolerability of Bisacodyl Sugar Coated Tablets, Simeticone Chewing Tablets and Their Combination in Constipation and Bloatedness
• Clinical Effects of Soluble Dietary Fiber Supplementation
• GOS Prebiotic Effect in Children Constipation
• Use of Novel Prebiotic Fiber for Targeted Dietary Management of Irritable Bowel Syndrome (Nutrabiotix Phase II)
• Lubiprostone for Children With Constipation
• Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation
• Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation
• Psyllium Fiber Versus Placebo in Early Treatment After STARR for Obstructed Defecation: a Double-blind RCT
• 12-Week Study of Plecanatide for CIC (The National CIC3 Study)
• Decreasing Narcotics in Advanced Pelvic Surgery
• Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients
• Efficacy and Safety of YKP10811 in Subjects With Irritable Bowel Syndrome With Constipation
• Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients
• Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial
• Lubiprostone in Children With Functional Constipation
• Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation
• Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation
• A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation
• Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC)
• 12-Week Study of Plecanatide for CIC (The CIC3 Study)
• Long Term Safety of Naldemedine
• Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation
• A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC).
• A Phase 2 Study to Evaluate the Safety and Efficacy of RM-131 in Patients With Parkinson's Disease & Chronic Constipation
• Methylnaltrexone for Opioid Induced Constipation
• A Single-blind, Dose-titration Study of KWA-0711 in Patients With Chronic Constipation
• A Single-blind, Dose-tapering Study of KWA-0711 in Patients With Chronic Constipation
• The Efficacy of AZD1722 in Constipation Predominant Irritable Bowel Syndrome (IBS-C)
• Open-label Extension (OLE) Study of Plecanatide for Chronic Idiopathic Constipation (CIC)
• Effect of Octreotide on the Colonic Motility in Pediatric Patients
• An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation
• The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
• Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
• Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
• Safety and Tolerability Extension Trial for Patients With Chronic Idiopathic Constipation
• Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003)
• A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia
• Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
• Polyethylene Glycol for Childhood Constipation
• Lactobacillus Reuteri in Adult With Functional Chronic Constipation
• The Colonic Transit Time: a Modifiable Determinant of Intestinal Production and Uptake of Microbial Metabolites?
• Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions
• Efficacy and Safety Trial of Elobixibat in Patients With Chronic Idiopathic Constipation
• 26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation
• A Trial of Three Types of Enemas Used to Treat Functional Constipation in Children
• A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation
• Effect of Propofol on Internal Anal Sphincter Pressure During ARM
• Electroacupuncture for the Treatment of Functional Constipation
• Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation
• Methylnaltrexone Use for Opioid-induced Postoperative Constipation
• The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)
• A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
• A Non-interventional, Observational Study for Targinact® Treatment in Patients With Chronic Severe Pain
• Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity
• Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
• A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation
• A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation
• MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery
• A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults
• Evaluation of Clinical Equivalence Between Two Lubiprostone Products in the Treatment of Chronic Idiopathic Constipation
• Prucalopride Subjects With Renal Impairment
• Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention
• Prucalopride in Paediatric Subjects, With Functional Faecal Retention
• TD-1211 Single-Dose Study in Elderly and Young Healthy Subjects
• Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
• Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol
• Mode of Action of Moviprep
• Impact of Laxative Therapy With Lactulose in the Evolution of Organ Dysfunction in Critically Ill Patients.
• A Exploratory Study of KWA-0711 in Patients With Chronic Idiopathic Constipation (CIC)
• Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol
• Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children
• Maintenance Treatment for Children With Constipation
• Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118
• Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
• A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation
• Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective
• A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation
• Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation
• Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation
• A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation
• Lubiprostone and Mucus Secretion in Patients With Chronic Constipation
• A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy
• A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy
• The Plecanatide Chronic Idiopathic Constipation (CIC) Study
• A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
• Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain
• Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years
• ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)
• Efficacy and Safety of Acupuncture for Functional Constipation
• A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)
• A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation
• Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain
• ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)
• Evaluation of Clinical Equivalence Between Two Lubiprostone Products
• Compassionate Use Study of Methylnaltrexone
• Effect of TU-100 in Patients With Functional Constipation
• A Study to Evaluate the Safety and Efficacy of RDX5791 for the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS-C)
• Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
• Investigation of KLYX in Patients With Constipation
• A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation
• Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome
• Prucalopride in Pediatric Subjects With Functional Constipation
• Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
• Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
• BLI801 Laxative in Constipated Adults
• Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation
• Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
• Trial for Quantity-Effect Relationship of Acupuncture With Two-ways Regulation to Treat Functional Enteropathy
• Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation
• Study Assessing the Efficacy of Eductyl® for the Treatment of Patients With Dyschesia
• Lubiprostone in Patients With Multiple Sclerosis Associated Constipation
• Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515)
• Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
• Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.
• Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients
• A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain
• The Effectiveness of Lubiprostone in Constipated Diabetics
• Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation
• Proof-of-Principle Study of TC-6499 in the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS)
• Evaluation of Prucalopride in Male Subjects With Chronic Constipation.
• Effect of TU-100 on Rectal Compliance, Rectal Sensation and Small Bowel and Colonic Transit in Females With Constipation
• Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation
• An Efficacy and Safety Study of Prucalopride in Participants With Chronic Constipation
• Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
• A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy
• ALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC)
• Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications
• Effect of Lubiprostone on Small Bowel Contractions in Female Patients With Constipation Irritable Bowel Syndrome (C-IBS)
• Study to Evaluate Long-Term Tolerability and Safety of Oral Prucalopride in Chronic Constipation
• Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients
• SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation
• Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit
• A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation
• Effect of Ileal Bile Acid Transporter Inhibitor in Functional Constipation
• Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation
• Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients
• Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation
• Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
• Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen
• Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment.
• Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain
• Study of Efficacy of Association of Senna Alexandrina Mill and Associations on Functional Intestinal Constipation
• Study to Evaluate Long-Term Safety, Tolerability, and Satisfaction With Prucalopride in Chronic Constipation
• Naloxone SR Capsules in Patients With Opioid Induced Constipation
• Can Methylnaltrexone Safely Treat Opioid Related Constipation in the Emergency Department?
• Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation
• Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome
• Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• Study Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-Constipation
• Intestinal Microecology in Chronic Constipation
• Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
• Cheno Effect on Transit in Health and IBS-C
• Efficacy of Eductyl® Versus Placebo for Treatment of Dyschesia
• Amitiza in Constipation Associated With PD (Parkinson's Disease)
• Thorough Corrected QT Interval (QTc) Study To Evaluate Possible Effects of Prucalopride on ECG Parameters
• OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
• Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients
• Effects of Oral PEG 3350 on Electrolyte Balance
• Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills
• Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects
• Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
• Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation
• Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients
• Constipation Associated With Irritable Bowel Syndrome (IBS-C)
• A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease
• Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216)
• An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
• Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation
• Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome
• Domperidone for Relief of Gastrointestinal Disorders
• Comparison of TCM and Laxatives for Adults With Chronic Constipation
• Randomized Trial of Mosapride Versus Placebo in the Treatment of Constipation-Predominant Irritable Bowel Syndrome
• An Effectiveness and Safety Study of Chinese Herbal Medicine for Functional Constipation
• An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
• Trial of Linaclotide in Patients With Chronic Constipation
• A Preference Study Comparing Kristalose® and Liquid Lactulose
• Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic Fibrosis
• Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness
• Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness
• Lubiprostone as a Treatment for Constipation in Parkinson's Disease
• Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation
• Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures
• Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
• Evaluation of the Safety and Tolerability of Prucalopride in Constipated Elderly Subjects Living in a Nursing Facility
• Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
• Long-Term Safety of Renzapride in Women With Constipation-Predominant Irritable Bowel Syndrome (IBS-C)
• Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain
• Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation
• A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)
• Efficacy and Safety Study of Prucalopride for the Re-Treatment of Chronic Constipation
• Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation
• SAT vs Escitalopram for Rectal Hypersensitivity
• A Pilot Study of a New PEG3350 Dose Formulation For Use in Constipated Children
• A Pilot Efficacy Evaluation of BLI-801 as a Laxative in Constipated Adults
• Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation
• Sodium Picosulphate vs. Placebo in Functional Constipation
• Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation
• Prucalopride in Patients With Chronic Idiopathic Constipation
• The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery
• A Randomized, Double-blind, Placebo-controlled Multicenter Study to Assess the Efficacy, Safety and Tolerability of Tegaserod 2 mg Bid vs Placebo in Patients With Chronic Constipation
• Study of Effect of Tegaserod on Small and Large Bowel Transit by Scintigraphic Method
• Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain
• A Study of the Safety and Effectiveness of DDP733 in Treating IBS With Constipation in Females
• Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain
• Dulcolax vs Placebo in Functional Constipation
• Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation
• A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain
• A Treatment Investigational New Drug (tIND) Program of Tegaserod in Women With Irritable Bowel Syndrome With Constipation or With Chronic Idiopathic Constipation
• A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional Constipation
• Phase II, Randomized, Placebo-Controlled Study of ATI-7505 in Patients With Chronic Idiopathic Constipation
• A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride
• Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation
• Efficacy and Safety Study of Prucalopride for the Treatment of Elderly Patients With Chronic Constipation
• Efficacy and Safety Study of Prucalopride for the Treatment of Patients With Chronic Constipation
• Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
• Comparison Trial of Enema vs. PEG 3350 for Constipation
• Randomized, Double-blind, Dose-range-finding, Phase 2 Study of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
• Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation
• Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects
• Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer
• Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
• Oxycodone-naloxone in Relieving Opioid-related Constipation
• Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation
• Movicol in Childhood Constipation (ProMotion Study)
• An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children
• Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children
• Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation
• Study of Methylnaltrexone (MNTX) for the Relief of Constipation
• A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients
• Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
• Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation
• Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)
• Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation
• Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain
• Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain
• Effect of Chinese Herb on Chronic Constipation for Residents in Long-Term Care Units
• Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients
• Clinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid
• A Pilot Study of a New MiraLax® Dose Formulation For Use in Constipated Children
• Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects
• Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation
• A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation
• The Effects of Tegaserod vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia
• Use of Pyridostigmine for Constipation in Diabetics
• Study of Long-term Use of Forlax® in Elderly Patients With Chronic Constipation
• Investigation of the Safety and Efficacy of Renzapride in Constipation Predominant Irritable Bowel Syndrome (IBS)
• Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
• Phase 2 Study of MD-1100 Acetate on Gastrointestinal Transit in Patients With C-IBS
• Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
• To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence.
• Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
• DARWIN Study: A Randomization/Withdrawal Efficacy Study of Dexloxiglumide in Constipation-Predominant Irritable Bowel Syndrome (C-IBS)
• A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of DDP733 for IBS-c
• Preference of Tegaserod vs. PEG 3350 in Patients With Constipation
• The Effect of Tegaserod on Patterns of Flow in the Small Bowel of Patients With Irritable Bowel Syndrome (IBS)
• An Open Label Study of Chronic Polyethyleneglycol3350 Use in Constipated Patients
• Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics
• Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients
• Polyethyleneglycol3350 vs Tegaserod in Treatment of Patients With Chronic Constipation
• Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications
• PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children
• Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation
• Assessment of Efficacy and Safety of Tegaserod in Male Patients With Chronic Constipation.
• An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation
• Biofeedback for Dyssynergic Constipation
• Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication
• Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain
• Treatment of Functional Bowel Disorders
• Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery