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Clinical Trials for Heart Defects, Congenital

• Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
• Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery
• Theophylline Effects in the Fontan Circulation
• " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "
• The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot
• Ultrasound-Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Surgery
• DEX vs SEVO in Congenital Heart Surgery
• The Role of Dexmedetomidine As Myocardial Protection In Pediatric Cyanotic Congenital Heart Disease Undergoing Open Cardiac Surgery Using Cardiopulmonary Bypass Machine: A Preliminary Study
• A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
• A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)
• Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass
• Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery
• Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV
• Dopamine Versus Norepinephrine Under General Anesthesia
• Dexmedetomidine Neuroprotection in Pediatric Cardiac Surgery
• Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass
• ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery
• Nitric Oxide During Cardiopulmonary Bypass in Neonates to Reduce Risk of Acute Kidney Injury
• Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass
• NO During CPB in Neonates to Reduce Risk of AKI
• Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy
• Propofol vs Sevoflurane in Cyanotic Congenital Heart Disease
• Use of Oxandrolone to Promote Growth in Infants With HLHS
• Clinical Study to Evaluate Efficacy and Safety of DA-1229 in Patients With CAVD
• Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow
• Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
• Nitric Oxide During CPB to Reduce AKI in Neonates
• The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
• An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients.
• Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease
• Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery
• The Effect of Dexmedetomidine on Kidney Perfusion in Paediatric Patients
• Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease
• Paravertebral Nerve Blocks in Neonates
• STeroids to REduce Systemic Inflammation After Infant Heart Surgery
• Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children
• Dexmedetomidine and the Inflammatory Response in Pediatric Cardiac Surgery
• Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study
• Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects
• Maternal Hyperoxygenation in Congenital Heart Disease
• Early Use of Vasopressin in Post-Fontan Management
• Custodiol Versus Blood Cardioplegaia in Paediatric Cardiac Surgery
• Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function
• Remote Preconditioning and Myocardial Protection
• Acute Effects of Inhaled Treprostinil in Fontan Patients
• Feraheme As An MRI Contrast Agent For Pediatric Congenital Heart Disease
• COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
• Effect of Dexmedetomidine on Pacemaker Function Following Cardiac Surgery
• Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril
• Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease
• Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery
• Intraoperative Dexamethasone in Pediatric Cardiac Surgery
• Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial
• Ulinastatin Injection in in Pediatric Patients Undergoing Open Heart Surgery
• Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation
• Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized Study
• Rejuvenated, Washed Packed Red Blood Cells in Pediatric Cardiac Surgery
• The Management of Systemic-Pulmonary Collateral Blood Flow in Cyanotic Children During Cardiopulmonary Bypass - Pilot Study
• Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary Bypass
• Evaluation of Safety and Efficacy of Lumason in Pediatric Echocardiography
• Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation
• Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease?
• Randomized Trial of Maternal Progesterone Therapy
• Tranexamic Acid Effect on Platelet Aggregation Following Infant Cardiopulmonary Bypass
• Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery
• Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol
• Ambrisentan in Single Ventricle
• Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery
• Post-bypass Prophylactic IVIG in Infants and Neonates
• Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System
• Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension
• The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease
• Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot
• The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates
• The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI
• Evaluating Precision of Therapy - Milrinone
• Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasE
• Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood Flow
• Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)
• Bosentan Therapy in Children With Functional Single Ventricle
• Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery
• Pre-operative Prophylaxis With Vancomycin and Cefazolin in Pediatric Cardiovascular Surgery Patients
• Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients
• Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
• Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
• Fontan Patients: Comprehensive Evaluation of Pulmonary Circulation and Ventricular Function
• Activated Recombinant Human Factor VII Following Cardiac Bypass Surgery for Paediatric Congenital Heart Disease
• Drug Therapy and Surgery in Congenital Heart Disease With Pulmonary Hypertension
• Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions
• The Myocardial Protective Effects of a Moderate-potassium Blood Cardioplegia in Pediatric Cardiac Surgery
• The Protective Effects of Sevoflurane in Pediatric Cardiac Surgery
• Preventing Brain Injury in Infants With Congenital Heart Disease
• Study of Inhaled Iloprost for the Treatment of Pulmonary Hypertension After Repair of Congenital Heart Disease
• Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease
• Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology.
• Real-time MRI Right Heart Catheterization Using Passive Catheters
• Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
• Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery
• Effect of Simvastatin on Cardiac Function
• Spironolactone in Adult Congenital Heart Disease
• Tranexamic Acid in Pediatric Cardiac Surgery
• Endothelin Blockade in Patients With Single Ventricle Physiology
• Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients
• Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO)
• The Effects of Inhaled Nitric Oxide After Fontan Operation
• Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
• Myocardial Protection With Adenosine Preconditioning
• Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children
• Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation
• Reversibility by Sildenafil of Exercise-Induced Abnormal Right Ventricular Pressure Response in ASD and VSD-Operated Patients
• Parenteral Phenoxybenzamine During Congenital Heart Disease Surgery
• Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist
• Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing
• Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease
• Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass
• Pilot Study of Inhaled Nitric Oxide to Treat Pulmonary Insufficiency in Congenital Heart Disease
• Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
• Erythropoetin Neuroprotection for Neonatal Cardiac Surgery
• The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease
• Iron Prophylaxis for Anemia in Infants With Cyanotic Congenital Heart Disease
• Erythropoietin and Pediatric Cardiac Surgery
• SPECS: Safe Pediatric Euglycemia in Cardiac Surgery
• Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation
• N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study)
• Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
• Nesiritide Use Following Cardiac Surgery in Infants
• Cylexin for Reduction of Reperfusion Injury in Infant Heart Surgery
• Citrulline for Children Undergoing Cardiopulmonary Bypass Surgery
• Hypertonic Saline Dextran in Pediatric Cardiac Surgery
• Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)
• Angiotensin Converting Enzyme Inhibition in Children With Mitral Regurgitation
• Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network
• Study of Triostat in Infants During Heart Surgery
• Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure
• Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects
• Management of Patent Ductus in Premature Infants