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Clinical Trials for Malaria, Falciparum

• A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants
• Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawi
• Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo
• Mass Vaccine and Drug Administration, Bangladesh
• Efficacy, Safety and Tolerability of KLU156 in Adults and Children ≥ 5 kg Body Weight With Uncomplicated P. Falciparum Malaria
• Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba Regency
• Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial
• Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
• Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)
• Child Health and Infection With Low Density (CHILD) Malaria
• Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali
• First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367
• Coadministration of GA2 Sporozoites With Adjuvants
• A PK/PD Study of Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria
• Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults
• Comparing Chemoprevention Approaches for School-based Malaria Control
• Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine
• Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali
• Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites
• Therapeutic Efficacy Study of AL and DP in Western Kenya
• Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of Chocó (Colombia)
• Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities
• Adjunctive Ivermectin Mass Drug Administration for Malaria Control
• Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon
• Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malaria
• To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria
• Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2)
• Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde
• Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria
• Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study
• Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites
• Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria
• A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults
• Nitrite Infusion in Children With Malaria
• Controlled Human Malaria Infection Transmission Model - Phase A
• A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults
• Effect of Paracetamol on Kidney Function in Severe Malaria
• TES Artemether-lumefantrine for Pf and Chloroquine (CQ) for Pv
• Seasonal Malaria Chemoprevention With Dihydroartemisin Piperaquin vs. Sulfadoxine-pyrimethamin+Amodiaquin
• Additional Screening With Sensitives RDTs and Malaria
• Mass Screening and Treatment for Reduction of Falciparum Malaria
• Short Course Radical Cure of P. Vivax Malaria in Nepal
• Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission
• Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials
• A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia)
• A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.
• Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas
• Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections
• Safety and Efficacy of NF135 CPS Immunization
• Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic Republic
• Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in Zanzibar
• Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005
• Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar
• Drug Combinations of Atovaquone-Proguanil (AP) With ACT
• Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzan
• Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2
• Extended Duration Artemether-lumefantrine Treatment for Malaria in Children
• Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania
• Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam
• Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.
• "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania"
• Cohort Event Monitoring Study of Pyramax®
• Chemoprotective Activity of MMV390048 in PfSPZ Challenge Model
• Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)
• Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)
• Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya
• Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa
• MMV390048 POC in Patients With P. Vivax and P. Falciparum Malaria
• SJ733 Induced Blood Stage Malaria Challenge Study
• Methylene Blue Against Falciparum Malaria in Burkina Faso
• Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar
• A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607
• In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria
• Effect of Imatinib on Suppression of Malaria Parasites in Patients With Uncomplicated Plasmodium Falciparum Malaria
• Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia
• P. Falciparum Resistance to Artemisinin in Vietnam
• Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil
• DSM265 Prophylaxis of Plasmodium Falciparum Malaria
• Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to Mosquitos
• To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar
• A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)
• DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria
• Safety and Tolerability of Low Dose Primaquine
• Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria
• Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali
• Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia
• Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesia
• MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants
• Evaluation of Fosmidomycin and Piperaquine in the Treatment of Acute Falciparum Malaria
• DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax
• Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria.
• Assessment of Artesunate/Mefloquine in the Peruvian Amazon
• Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.
• Malaria in Early Life Study
• A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria
• Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO
• Targeted Chemo-elimination (TCE) of Malaria
• Antimalarial Drug Resistance With Assessment of Transmission Blocking Activity
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis
• Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger
• SPK Study in Afghanistan
• Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoites
• Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand
• Compare the Effectiveness Between Existing Treatment and New Treatment
• Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg
• Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria
• Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria
• Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children
• Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults
• Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malaria
• Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in Children
• Azithromycin Combination Therapy for the Treatment of Severe Malaria
• Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda
• Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria
• Tracking Resistance to Artemisinin (TRAC)
• Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Malawi
• Superiority of ArTiMist Versus Quinine in Children With Severe Malaria
• Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
• Food Interaction Study on the Pharmacokinetics of Eurartesim™ (DHA and PQP)in Healthy Male Adult Volunteers
• A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™
• Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
• Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection
• Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010
• EP1300 Polyepitope DNA Vaccine Against Plasmodium Falciparum Malaria
• Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparum
• Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria
• Study of Iron Absorption and Utilization in Asymptomatic Malaria
• Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers
• Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa
• Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in Children
• Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan
• Efficacy of ArTiMist™ in Children
• Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period
• EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-immune Adults
• Extended-dose Chloroquine (ECQ) for Resistant Falciparum Malaria Among Afghan Refugees in Pakistan
• Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso
• Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
• Trial of Artesunate Combination Therapy in Pakistan
• Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon
• Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia
• A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects
• Effectiveness of Artemisinin Combination Regimens in Falciparum Malaria
• A Bioequivalence Study Comparing Amodiaquine Tablet (Pfizer) To Amodiaquine Tablets (Arsuamoon-Guilin China) In Healthy Subjects
• Bioequivalence Study Comparing Artesunate Tablet To Arsuamoon® Tablets (Guilin-China) In Healthy Subjects
• Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali
• Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania
• A Bioequivalence Study Comparing Camoquin® Suspension (Pfizer) To Flavoquine® Tablets (Sanofi Aventis) In Healthy Subjects
• Artemisinin Resistance in Cambodia II
• Evaluation of Safety and Efficacy of Artemether-Lumefantrine Tablets in African Infants and Children With Uncomplicated P. Falciparum Malaria
• Pharmacokinetic of Mefloquine-Artesunate in Plasmodium Falciparum Malaria Infection in Pregnancy
• Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
• A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan
• Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa
• Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria
• Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients
• Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
• Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum Malaria
• Mass-Drug Administration to Reduce Malaria Transmission
• Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western Cambodia
• Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
• Artemisinin Resistance in Cambodia
• Tolerability and Efficacy of CD+A Compared to AQ+SP for the Treatment of P.Falciparum Malaria in Rwandan Children
• Phase II Dose Ranging Study of Artesunate
• Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
• Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria
• Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients
• Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients
• Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria.
• Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia
• Randomized Trial on Effectiveness of ACTs in Ghana
• Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria
• Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
• RBx11160 Phase II Dose Ranging Study RBx/MMV05-06
• Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh
• Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly
• Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malaria
• Experimental Vaccine for Malaria in Adults in Mali
• Experimental Vaccine for Plasmodium Falciparum Malaria
• Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria
• Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria
• ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria
• Comparative Evaluation of the Safety and the Efficacy of 2 Antimalarials Depending on HIV Status
• SP Resistance and Falciparum Malaria Transmission
• Azithromycin Combination Therapy for Malaria
• Effect of Antimalarial Treatment on Gametocyte Carriage in Asymptomatic P. Falciparum
• A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria
• Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso
• Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria
• Efficacy, Safety and Tolerability of Co-artemether in Non-immune Travelers
• Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines
• Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi
• Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawi
• Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in Peru
• ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan
• A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia.
• To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia
• A Randomized Trial of Coartemether and Artekin for the Treatment of Uncomplicated Malaria in Papua, Indonesia.
• The Community Effectiveness of IPTi in Southern Tanzania
• Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria
• Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria
• Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
• Preventing Malaria During Pregnancy in Epidemic-prone Areas.
• The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Children
• Chloroquine and Amodiaquine for Treatment of Malaria in Children
• Pentoxifylline in Children With Malaria
• Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi
• CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi
• Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia
• Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America
• Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa
• Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum
• Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India