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Clinical Trials for Toxemia

• The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis
• Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis
• Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy
• Optimal Blood Pressure Treatment Thresholds Postpartum
• Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients
• Safety and Feasibility of Metformin for Sepsis Induced AKI
• Continuous Spinal Anesthesia Versus General Anesthesia in Sepsis
• Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality
• Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis
• Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
• Early Administration of Norepinephrine in Sepsis
• Alpha-Lipoic Acid in Patients With Sepsis
• The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension
• Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial
• Intensive Postpartum Antihypertensive Treatment
• Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis
• Alirocumab in Patients With Sepsis
• Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI)
• Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01)
• The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock
• Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome
• Zinc Supplementation in Pediatric Sepsis
• Effect of Montelukast Versus Co Enzyme in Sepsis
• Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
• GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS
• The Efficacy of YiQiFuMai Injection as an Adjunctive Treatment for Sepsis
• Outcome of High Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation
• Intravenously Administered M6229 in Critically Ill Sepsis Patients
• Clinical Efficacy of Megadose Vitamin C in Sepsis
• Early Vasopressors in Sepsis
• HAT for the Treatment of Sepsis Associated With NASTI
• Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis
• Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia
• Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure
• Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients
• Epirubicin for the Treatment of Sepsis & Septic Shock
• Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa
• Personalized Immunotherapy in Sepsis
• Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury
• Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
• SY-005 （Recombinant Human Annexin A5）in Patients With Sepsis
• Safety Study of Inhaled Carbon Monoxide to Treat Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)
• Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection
• Efficacy and Safety of Kukoamine B Mesilate in Sepsis Patients
• The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis
• Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
• Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis
• A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients
• Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
• The Effect of Esmolol on Patients With Sepsis
• Triple Therapy in Septic Shock Patients
• Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants
• Effects of Integrated Treatment of Traditional Medicine and Western Medicine for Sepsis-induced Cardiac Injury
• A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes
• Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery
• Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis
• Control of Fever in Septic Patients
• Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis
• Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
• Pentoxifylline Dose Optimization in Neonatal Sepsis
• Adjuvant Use of Neostigmine in Sepsis and Septic Shock.
• Efficacy and Safety of Vitamin A Treatment for Children With Sepsis
• Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock
• High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
• IgM-Enriched Immunoglobulin for Neonatal Sepsis
• NICU Antibiotics and Outcomes Trial
• Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock
• Azithromycin-Prevention in Labor Use Study (A-PLUS)
• Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study)
• Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
• Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients
• GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study
• Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.
• Comparison of Balanced Crystalloids and Normal Saline in Septic Patients
• Vitamin C & Thiamine in Sepsis
• The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy
• Vitamin C, Thiamine, and Steroids in Sepsis
• Pharmacokinetics of XueBiJing in Patients With Sepsis
• Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis
• Esomeprazole to Reduce Organ Failure in Sepsis
• Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
• Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonates
• Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
• Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)
• Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients
• The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
• A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis
• Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis
• 7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis
• Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis
• The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients
• The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis
• Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock
• The Efficacy of Xuebijing Injection on Sepsis
• Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients
• Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death
• Adrenal Cortical Function and Vitamin A Deficiency in Sepsis
• Midodrine Hydrochloride in Early Sepsis
• Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP)
• Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis
• Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis
• Dendritic Cells-Derived Exosomes in Human Sepsis
• Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis
• A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy
• Methylene Blue and Ozone in Early Sepsis
• Short-course Antimicrobial Therapy in Sepsis
• Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis
• The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy
• Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
• The Efficacy and Safety of Ta1 for Sepsis
• Immune Reconstitution of Immunosuppressed Sepsis Patients
• The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis
• High Dose Intravenous Ascorbic Acid in Severe Sepsis
• Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock
• The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia
• Vitamin D Status in Patients With Severe Sepsis
• Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock
• Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
• Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China
• A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients
• Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis
• Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock
• Safety, Tolerability and Efficacy of Ceftaroline in Paediatrics With Late-Onset Sepsis
• Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics
• Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis
• Dose Assessment of Melatonin in Sepsis Trial
• Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS
• A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis
• Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units
• Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis
• Pentoxifylline and Late Onset Sepsis in Preterm Infants
• Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis
• Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status
• The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis
• Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
• Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis
• Efficacy of Mw Vaccine in Treatment of Severe Sepsis
• Angiotensin II Antagonist in Severe Sepsis
• Prehospital Antibiotics Against Sepsis Trial
• Ubiquinol (Reduced COQ10) for Patients With Sepsis
• Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin
• Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock
• Methylene Blue in Severe Sepsis and Septic Shock
• ASpirin for Patients With SEPsis and SeptIc Shock
• Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial
• Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis
• Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis
• The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis
• Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy
• A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis
• Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis
• Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy
• Citrulline in Severe Sepsis
• Maternal and Neonatal Outcomes of the Use of Vasopressors to Treat Hypotension During Spinal Anesthesia for Cesarean
• Preemptive Resuscitation for Eradication of Septic Shock
• Ascorbic Acid (Vitamin C) Infusion in Human Sepsis
• Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
• Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.
• Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock
• Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis
• GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock
• Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
• The Effect of Moderate-Dose Steroid Therapy in Sepsis
• Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis
• Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension
• Hyperinsulinemic Therapy in Sepsis
• Clarithromycin as Immunomodulator for the Management of Sepsis
• Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant
• A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock
• A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock
• Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
• Immunomodulatory Properties of Ketamine in Sepsis
• Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients
• Simplified Antibiotic Therapy for Sepsis in Young Infants
• Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'
• The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)
• Statins for Acutely Injured Lungs From Sepsis
• Scandinavian Starch for Severe Sepsis/Septic Shock Trial
• Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh
• Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis
• Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis
• Fluid Resuscitation in Early Septic Shock
• Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis
• Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology
• Septic Encephalopathy and Late Cognitive Dysfunction
• Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study
• Efficacy of Thymosin alpha1 for Severe Sepsis
• Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis Patients
• Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis
• Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis
• Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure
• Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis
• Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
• An Open Label Study of Severe Sepsis in Adults
• The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death
• A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult
• Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
• Statins for the Early Treatment of Sepsis
• A Study in Sepsis Patients With Renal Failure
• Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
• Methylene Blue in Sepsis: A Randomized Controlled Trial
• Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis
• Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
• Pharmacokinetic of Ceftriaxone in Septic ICU Patients
• Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
• Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)
• Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
• Effect of Rosuvastatin in Abdominal Sepsis
• The Effects of HIV Protease Inhibitors in Severe Sepsis
• ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis
• Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.
• BaSES Trial: Basel Starch Evaluation in Sepsis
• Treatment Targets for Chronic Hypertension in Pregnancy
• Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
• Efficacy & Safety of Resatorvid in Adults With Severe Sepsis
• The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients
• Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation
• Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
• Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
• Unfractioned Heparin for Treatment of Sepsis
• GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults
• A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated)
• Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
• A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis
• A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis
• Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
• A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis
• Pleconaril Enteroviral Sepsis Syndrome
• Oral Calcium in Pregnant Women With Hypertension
• Calcium for Pre-Eclampsia Prevention (CPEP)