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Clinical Trials for Hypertension, Pulmonary

• Xenon MRI in Stable Pulmonary Hypertension (Jupiter AUGEAN)
• A Study to Learn How Safe the Study Treatment BAY2701250 is, How it Affects the Body and How it Moves Into, Through and Out of the Body in Healthy Male Participants When a Single Amount is Given as an Injection Into the Vein (Intravenous Infusion) o
• 129Xe MRI Cardiopulmonary
• Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
• Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
• Inhaled Versus Intravenous Milrinone for Patients Undergoing Mitral Valve Replacement Surgery
• A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Disease
• A Phase 2a Study of LAM-001 for the Treatment of PH
• Feasibility of Semaglutide in Advanced Lung Disease
• The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns
• A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2
• A Study of Macitentan in Children Below 2 Years of Age
• The Effect of Pituitrin on the Patients With Pulmonary Hypertension Undergoing Cardiac Surgery
• rhBNP in Type 3 Pulmonary Hypertension
• A Study to Evaluate the Efficacy, Safety and Tolerability of PDNO Infusion in Patients With Pulmonary Hypertension After Cardiopulmonary Bypass Surgery
• An Extension Study to Assess the Safety, Tolerability, and Effectiveness of the Long-Term Use of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
• MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD
• A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension
• First-in-human Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of C106 in Healthy Subjects
• Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH
• A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
• A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
• Dapagliflozin in Pulmonary Arterial Hypertension
• A Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease
• Investigation of H01 in Adults With Pulmonary Hypertension Including Interstitial Lung Disease (The SATURN Study).
• Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2
• Xenon MRI Pulm Hypertension
• Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH
• A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF
• Endovenous Sildenafil Early Management in Newborns Pulmonary Hypertension
• PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation
• Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn
• A First-in-human Study to Assess the Safety and Tolerability of PDNO
• A Study to Evaluate the Efficacy, Safety and Tolerability of PDNO Infusion in Covid-19 Patients With aPH
• Telemonitoring to Treat Group 2 Pulmonary Hypertension
• Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia
• Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension
• Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device
• A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)
• Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents
• Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
• THERAPY-HYBRID-BPA Trial
• Levosimendan Administration in Pulmonary Hypertension
• PGI2 Versus Nitroglycerine for Management of Pulmonary Hypertension After Valve Surgeries
• Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension
• A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study
• Copd Exacerbation and Pulmonary Hypertension Trial
• Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension
• Efficacy and Safety of Milrinone Versus Sildenafil in the Treatment of Neonates With Persistent Pulmonary Hypertension
• MK-5475 in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) (MK-5475-006)
• Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn
• Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
• A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension
• Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide
• Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema
• A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
• Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants
• A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH
• N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.
• Clinical Study of Adipose Derived Mesenchymal Stem Cells for Treatment of Pulmonary Arterial Hypertension
• Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
• Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease
• Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil
• Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
• A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag
• Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial Hypertension
• Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension
• A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).
• Upfront Combination Pulmonary Arterial Hypertension Therapy
• Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)
• Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
• Sildenafil in Hemodialysis Patients With Pulmonary Hypertension
• This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thro
• CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH
• A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment
• A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
• Effects of DHEA in Pulmonary Hypertension
• Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
• Metformin for Pulmonary Hypertension HFpEF
• A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
• Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients
• Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE
• Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia
• Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension
• L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
• Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF
• Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension
• A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)
• Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography
• Sildenafil in US Heart Failure Patients (SilHF-US)
• Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children
• A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.
• L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension
• Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil
• ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1)
• Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension
• Cardiometabolic Disease and Pulmonary Hypertension
• Spironolactone Therapy in Chronic Stable Right HF Trial
• Efficacy and Safety of Combination Ambrisentan and Tadalafil in Patients With Portopulmonary Hypertension
• The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension
• Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)
• Effect of Inhaled Albuterol in Pulmonary Hypertension
• Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2)
• Pulmonary Hypertension and Anastrozole Trial
• A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH)
• Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on Oxygen
• Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension
• Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
• Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension
• Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
• Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
• Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction
• Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD
• Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
• A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction
• Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary Hypertension
• Milrinone in Congenital Diaphragmatic Hernia
• Cell Proliferation in Pulmonary Hypertension. FDG-PET Comparison Between Patients and Healthy Subjects
• Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery
• Targeting Right Ventricle in Pulmonary Hypertension Gilead
• Examination of Ventavis (Iloprost) Inhalation Behavior Using the I-Neb AAD System in Patients With Pulmonary Arterial Hypertension When Switching the Iloprost Nebulizer Solution for Inhalation From 10 μg/mL (V10) to 20 μg/mL (V20)
• Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)
• Bleeding Frequency Under Anticoagulant Treatment in Pulmonary Hypertension
• Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure
• AZ, MZ, and the Pulmonary System Response to Hypoxia
• A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.
• Chronic Clinical Effect of Acetazolamide
• Acute Hemodynamic Effect of Acetazolamide in Pulmonary Hypertension
• Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders
• Pharmacodynamic Effects of Riociguat in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction
• Acute Effects of rhBNP in Patients With PH Associated With Acute Exacerbation of Chronic Pulmonary Disease
• A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects
• A Study of Stellate Ganglion Block and / or Reserpine in Group 2 Pulmonary Hypertension
• Macitentan in Pulmonary Hypertension of Sickle Cell Disease
• Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension
• An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE
• Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE
• Riociguat for Sarcoidosis Associated Pulmonary Hypertension
• Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
• Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary Hypertension
• ABI-009, an mTOR Inhibitor, for Patients With Severe Pulmonary Arterial Hypertension
• Epidemiology and Treatment Patterns of Paediatric PAH (Pulmonary Arterial Hypertension)
• Riociguat in Children With Pulmonary Arterial Hypertension (PAH)
• Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation
• Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients
• A Study to Understand the Treatment Patterns in Patients With Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension During a Switch of Treatment to Adempas in Real-life Clinical Practice
• Iloprost for Bridging to Heart Transplantation in PH
• Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)
• Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH)
• PDEI Following Mitral Valve Surgery in Patients With Pulmonary Hypertension
• Role of the Nitric Oxide (NO) in Pre-oxygenation Before Anesthetic Induction in Patients With a Pulmonary Hypertension in Cardiac Surgery. Pilot Study of Feasibility
• Sildenafil in Heart Failure With Reactive Pulmonary Hypertension
• Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH)
• 3 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPF
• Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn
• Use of Ventavis in Patients With Postembolic Residual Pulmonary Hypertension
• Safety of Terbogrel in Patients With Primary Pulmonary Hypertension
• Safety and Efficacy of Terbogrel in Patients With Primary Pulmonary Hypertension
• Regadenoson for Acute Vasoreactivity Testing in Pulmonary Hypertension
• Pulmonary Arterial Denervation in Patients With Pulmonary Hypertension Associated With the Left Heart Failure
• Use of Inhaled Nitric Oxide to Prevent Pulmonary Hypertension Associated to Stored Blood Transfusion
• Phase-II Study of the Use of PulmoBind for Molecular Imaging of Pulmonary Hypertension
• Measuring Outcomes In Patients With Pulmonary Arterial Hypertension Not on Active Treatment (MOTION)
• Inhaled Aerosolized Prostacyclin for Pulmonary Hypertension Requiring Inhaled Nitric Oxide
• Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep
• Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance
• Efficacy and Safety of Riociguat in Patients With Symptomatic Pulmonary Hypertension (PH) Associated With Idiopathic Interstitial Pneumonias (IIP)
• Study of Ranolazine in the Treatment of Pulmonary Hypertension Associated With Diastolic Left Ventricular Dysfunction
• Carvedilol PAH A Pilot Study of Efficacy and Safety
• Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH )
• Trimetazidine in Pulmonary Artery Hypertension
• EXPERT, EXPosurE Registry RiociguaT in Patients With Pulmonary Hypertension
• A Multiple Dose Titration Study of MK-8892 in Participants With Pulmonary Hypertension and Left Heart Disease (MK-8892-007)
• Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction
• Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
• Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure
• Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT
• Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude
• Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
• Riociguat Clinical Effects Studied in Patients With Insufficient Treatment Response to Phosphodiesterase-5 Inhibitor
• Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension
• Non-interventional Study on Compliance of Inhaled Treatment With Ventavis in Patient With Pulmonary Hypertension
• Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage
• Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery
• 11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension
• Hydroxyurea in Pulmonary Arterial Hypertension
• Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease
• Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
• 11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension
• Safety and Efficacy Study of HGP1207 in Patients With Pulmonary Hypertension
• Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure
• Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease
• Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation
• A Open Label Study to Assess the Long-term Safety, Tolerability and Efficacy of Ambrisentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
• Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure
• VasoREACTivity Testing With Intravenous SILdenafil in Patients With Precapillary Pulmonary Hypertension
• Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
• Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease
• Targeting the Right Ventricle in Pulmonary Hypertension
• A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)
• Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH.
• Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
• Treatment of Pulmonary Hypertension Associated COPD With Inhaled Treprostinil-1
• Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns
• Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD
• Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PH
• Inhaled Milrinone in Cardiac Surgery
• A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn
• A Randomized Trial of Udenafil Therapy in Patients With Mild Pulmonary Hypertension [ULTIMATE-Mild PHT]
• Pharmacokinetics of Sildenafil in Premature Infants
• Efficacy Study of Cardizem in Pulmonary Arterial Hypertension
• Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension
• Efficacy and Safety Study of Sodium Tanshinone IIA Sulfonate on Pulmonary Hypertension
• Effect of Brief Nebulization of Milrinone on Pulmonary Arterial Pressure Before Cardiopulmonary Bypass on Mitral Valve Surgery Patients
• Sildenafil Versus Placebo in Chronic Heart Failure
• Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
• PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)
• Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease
• The Safety Evaluation of Drug Combinations Against High Altitude Pulmonary Hypertension
• Sildenofil in Persistent Pulmonary Hypertension in Newborns
• The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy Volunteers
• Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting
• Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension
• Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac Surgery
• Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Pulmonary Hypertension
• Inhaled Iloprost (Ventavis): Efficacy, Safety, and Pharmacokinetics (PK) Confirmation Study
• Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension
• Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)
• Study of a New Thermo Stable Formulation of Epoprostenol Sodium to Treat Pulmonary Arterial Hypertension (PAH)
• Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH)
• Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
• Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or Hypoxia
• SPHERIC-1. Sildenafil and Pulmonary HypERtension In COPD
• Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)
• Inhaled Nitrite in Subjects With Pulmonary Hypertension
• Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension
• Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH)
• Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects
• Study of Sildenafil to Treat Newborns With Persistent Pulmonary Hypertension
• Drug Use Investigation for VOLIBRIS® (Ambrisentan) (Pulmonary Arterial Hypertension)
• Qutenza®-Remodulin® in Pulmonary Arterial Hypertension Patients
• Persistent Pulmonary Hypertension of the Newborn
• Inhaled Iloprost in the Treatment of Patients With Pulmonary Hypertension up to 4 Years
• Nitro Oxide Inhalation Continued With Sildenafil on Neonatal Persistent Pulmonary Hypertension
• Vasopressin and Inhaled Prostacyclin in Pediatric Pulmonary Hypertension
• The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
• IV Sildenafil Persistent Pulmonary Hypertension Of The Newborn
• Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration
• Long-term Ambrisentan Extension Study for Pediatric Patients Who Participated in AMB112529
• Efficacy and Safety of Ambrisentan in Children 8-18yrs
• Safely Change From Bosentan to Ambrisentan in Pulmonary Hypertension
• Tadalafil for Sarcoidosis Associated Pulmonary Hypertension
• Study of Inhaled Iloprost for the Treatment of Pulmonary Hypertension After Repair of Congenital Heart Disease
• Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery
• Safety of SonoVue on Pulmonary Hemodynamics
• A 48-week Study of the Effect of Dual Therapy (Inhaled Treprostinil and Tadafafil) Versus Monotherapy (Tadalafil).
• Treprostinil Combined With Tadalafil for Pulmonary Hypertension
• Real-time MRI Right Heart Catheterization Using Passive Catheters
• Hyperpolarized 129Xe MRI for Imaging Pulmonary Function
• Iloprost Effects on Gas Exchange and Pulmonary Mechanics
• Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults
• Bosentan for Severe Mitral Valve Dysfunction
• The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain
• Ambrisentan in Patients With Porto-pulmonary Hypertension A Multicenter Open Label Trial
• Effects of Propofol and Isoflurane on Pulmonary Vascular Resistance
• Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
• A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
• Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension?
• Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.
• A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)
• Ranolazine and Pulmonary Hypertension
• A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Diastolic Dysfunction
• Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failure
• Clevidipine for Vasoreactivity Evaluation of the Pulmonary Arterial Bed
• Inhaled Iloprost for Disproportionate Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease (COPD)
• A Dose Response Study of UT-15C SR in Patients With Exercise-Induced Pulmonary Hypertension
• Effectiveness of the Vasodilator Test With Revatio, Made in Patients With Acute Pulmonary Hypertension
• Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn
• Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension
• Sedation With Dexmedetomidine During Cardiac Catheterization
• Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN)
• A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction
• Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics
• Hypertension Study of Ventavis® Inhalation Therapy in the Treatment of Patients With Pulmonary Arterial Hypertension (VENIS)
• Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary Hypertension
• Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan
• Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
• A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
• Anticoagulation For Pulmonary Hypertension in Sickle Cell Disease
• A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension
• Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension
• Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients
• Effect of Esomeprazole on the Pharmacokinetics of Oral Treprostinil
• Effect of Food on the Pharmacokinetics of Oral Treprostinil
• Study of the Effects of Iron on Lung Blood Pressure at High Altitude
• Study of the Effects of Iron Levels on the Lungs at High Altitude
• To Provide Sildenafil Therapy To Eligible Adult Patients With Pulmonary Arterial Hypertension For 112 Weeks
• Iloprost in High Risk Cardiac Surgical Patients
• Safety and Efficacy Study of Bosentan in Progressive Pulmonary Sarcoidosis
• Inhaled Nitric Oxide (INO) In Hypoxic Respiratory Failure
• BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension
• Early Therapy of Pulmonary Arterial Hypertension
• Efficacy and Safety of Oral UT-15C Tablets to Treat Pulmonary Arterial Hypertension
• Post-Marketing Surveillance of Ventavis® in Chinese Patients With Primary Pulmonary Hypertension (PPH)
• ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
• Evaluate Effect of Optison on Pulmonary Artery Systolic Pressure (PASP) and Pulmonary Vascular Resistance (PVR).
• Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary Hypertension
• A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease
• BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension
• Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease
• A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.
• A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension
• Ambrisentan (Letairis) for Sarcoidosis Associated Pulmonary Hypertension
• Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan
• Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung Disease
• Insulin Resistance in Pulmonary Arterial Hypertension
• Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary Hypertension
• Milrinone Inhaled in Cardiac Surgery
• Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure
• A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With Pulmonary Arterial Hypertension (PAH)
• Does Sildenafil Increase Exercise Performance in Air Pollution?
• Sildenafil IV Bolus Study
• Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil
• Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety
• Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)
• Study Evaluating the Addition of Sildenafil to Bosentan Therapy in Pulmonary Arterial Hypertension
• Study of Ambrisentan in Participants With Pulmonary Hypertension
• Reversibility by Sildenafil of Exercise-Induced Abnormal Right Ventricular Pressure Response in ASD and VSD-Operated Patients
• FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
• The Role of Endothelin in Pulmonary Hypertension
• Sildenafil for Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension
• The Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension
• Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension
• Effects of Inhaled Treprostinil Sodium for the Treatment of Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
• Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)
• Interaction Study in Patients With Pulmonary Hypertension and Stable Treatment of Sildenafil 20 mg TID
• An Observational Study For Ambrisentan
• Effects of Bosentan on Respiratory Mechanics
• An Open-Label Study to Evaluate the Safety and Efficacy of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
• Special Investigation For Long-Term Use Of Sildenafil (Regulatory Post Marketing Commitment Plan)
• A Study to Assess the Efficacy and Safety of 20, 40, and 80mg of Sildenafil Three Times a Day in the Treatment of Pulmonary Arterial Hypertension
• Rapid Switch From Flolan to Remodulin in the Outpatient Clinic
• Single Dose Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension.
• Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study
• Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness
• Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing
• Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil
• Atorvastatin in Pulmonary Hypertension
• Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure
• Pulmonary Artery Remodelling With Bosentan
• Pharmacogenomics in Pulmonary Arterial Hypertension
• Safety Study of Gleevec® in Children With Pulmonary Hypertension
• Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
• Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults
• Single Dose Escalation Study in Patients With Chronic Heart Failure
• Iloprost in Gas Exchange/Pulm Mechanics in Chronic Obstructive Pulmonary Disease (COPD)
• A Study to Evaluate GSK1325760A - a Long-Term Extension Study
• Study the Safety and Effectiveness of Tadalafil on High Blood Pressure in the Blood Vessel Going From the Heart to the Lungs
• Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension
• Simvatstatin Used to Treat Pulmonary Hypertension
• Losartan Therapy in Pulmonary Hypertension
• Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
• Effect of Tadalafil in Chronic Obstructive Lung Disease Patients Suffering From Secondary Pulmonary Hypertension
• Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease
• Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD)
• The "Power 15 Study": Safety Study of Inhalation of Ventavis With the Power Disc-15 Setting
• Vasoactive Intestinal Peptide in COPD
• Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery
• Transitioning To IV Remodulin From Ventavis in Patients With PAH: Safety, Efficacy and Treatment Satisfaction
• An Open Multiple Dose Titration Study In Patients With Pulmonary Hypertension
• Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension
• Trial of Iloprost in Pulmonary Hypertension Secondary to Pulmonary Fibrosis
• Effect of Bosentan on Exercise Capacity at High Altitude
• Phase 2 Extension Study of Ambrisentan in Pulmonary Arterial Hypertension
• Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension
• Aerosolized Randomized Iloprost Study II (AIR - II) Long-Term Safety, Tolerability, and Clinical Effects of Iloprost Inhalation in Patients With Primary or Secondary Pulmonary Hypertension
• Inhaled Iloprost for the Treatment of Persistent Pulmonary Hypertension in the Term and Near Term Infants.
• Inhaled Iloprost for Sarcoidosis-associated Pulmonary Hypertension
• A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
• Safety and Efficacy Study of Ambrisentan in Subjects With Pulmonary Hypertension
• Placebo Controlled Trial of Bosentan in Scleroderma Patients
• Safety, Efficacy and Treatment Satisfaction in Patients With PAH Rapidly Switched From Epoprostenol to Remodulin
• A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
• Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis
• Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension
• Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension
• Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
• Safety and Effectiveness of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
• Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
• Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
• Sildenafil to Treat HIV-Associated Pulmonary Hypertension
• FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)
• FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
• Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension
• Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
• Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension
• Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH)
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)
• The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial Hypertension
• Prevention of High Altitude Pulmonary Edema
• Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
• Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia
• Observation of Patients With Primary Pulmonary Hypertension Receiving Prescribed Ventavis Inhalation Therapy Regarding Safety and Efficacy for up to 4 Years
• Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension
• Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
• Treatment of Elevated Arterial Pulmonary Pressure With Inhaled Iloprost
• Natrecor for Pulmonary Hypertension in Lung Transplants
• Serotonin Transporter Inhibitor Escitalopram in Pulmonary Hypertension
• Safety Follow-up Study of Inhaled Iloprost in Patients With Pulmonary Hypertension
• Simvastatin as a Treatment for Pulmonary Hypertension
• Study to Assess the Longterm Safety of Sildenafil Citrate in Patients With Pulmonary Arterial Hypertension
• The Efficacy and Safety of Sildenafil Citrate Used in Combination With Intravenous Epoprostenol in PAH
• Efficacy of Type-5 Phosphodiesterase Inhibitors in Primary and Secondary Pulmonary Hypertension
• Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH)
• Sildenafil and Pulmonary Artery Pressure
• NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
• Chronic Sildenafil for Severe Diaphragmatic Hernia
• PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension
• Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis
• A Study of Aspirin and Clopidogrel in Patients With Idiopathic Pulmonary Arterial Hypertension
• Endothelial Cell Dysfunction in Pulmonary Hypertension
• Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II
• ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)
• Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH)
• The Effect of Tracleer® on Male Fertility
• Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension
• Natrecor in Pulmonary Hypertension
• A Transition Study From Flolan® to Remodulin® in Patients With Pulmonary Arterial Hypertension
• Study of BSF 208075 Evaluating Exercise Capacity in Patients With Pulmonary Arterial Hypertension
• Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
• Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension
• Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension
• Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure
• Inhaled Nitric Oxide Study for Respiratory Failure in Newborns
• Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
• Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension
• Phase III Randomized Study of UT-15 in Patients With Primary Pulmonary Hypertension
• Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)