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Clinical Trials for Alcoholism

• Experimental Study on Alcohol Use and Behavior in Young Adults
• Efficacy of Baclofen Vs Naltrexon in Achieving & Maintaining Abstinence in Alcohol Dependence.
• Psilocybin-Assisted Therapy for Severe Alcohol Use Disorder
• A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine
• The Effects of Sex Hormones and Alcohol on Sleep
• Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
• Neural Correlates During Alcohol Intoxication
• Ketamine for Combined Depression and Alcohol Use Disorder
• The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
• Methylphenidate and Response to Alcohol Cues
• Semaglutide Therapy for Alcohol Reduction (STAR)
• Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1
• Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder
• Intranasal Insulin for Treatment of Alcohol Use Disorder
• MDMA for AUD/PTSD Comorbidity
• Clinical Study of Ligustrazine in Treating Alcohol Addiction
• Impulsivity Domains and Subjective Response
• Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity?
• Randomized, Controlled Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD)
• Semaglutide Therapy for Alcohol Reduction - Tulsa
• Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
• Citicoline in Youth Alcohol Use Disorder
• Cannabidiol as an add-on Treatment During Inpatient Alcohol Cessation in Patients With Severe Alcohol Use Disorder: a Phase ii Trial
• Phase 1b Repeat Dose Study of DCR-AUD in Healthy Volunteers
• Emergency Department-Initiated Medications for Alcohol Use Disorder
• Spironolactone in Alcohol Use Disorder (SAUD)
• Pregnenolone for the Treatment of Alcohol Use Disorder
• Cytisine for Smoking Cessation
• A Randomised, Controlled Trial of MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder
• Testing a Novel Therapeutic Strategy for Comorbid Post-Traumatic Stress Disorder and Alcohol Use Disorder
• An Open-Label, Single Dose Study in Patients With Alcohol Use Disorder
• Ketamine for the Treatment for Alcohol Use Disorder in the ED
• Orexin Receptor Antagonists as Modulators of Threat Sensitivity in Individuals With Alcohol Use Disorder
• Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)
• A Clinical Trial to Assess Pharmacokinetic Profiles and Safety of IVL3004
• Alcohol Use Disorder and Cannabidiol
• Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
• Semaglutide for Alcohol Use Disorder
• LSD Treatment for Persons With Alcohol Use Disorder
• Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep
• Psilocybin-assisted Psychotherapy for Treatment of Alcohol Use Disorder
• Psilocybin-assisted Therapy for Treatment of Alcohol Use Disorder
• A Randomized, Double-blind Placebo-Controlled Study of Ibudilast for Treating Alcohol Use Disorder
• A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use Disorder
• Cannabis' Impact on Alcohol Consumption
• The Efficacy and Neurobehavioural Mechanism of Cannabidiol (CBD) for Alcohol Dependence
• Enhancing the Effects of Adolescent Alcohol Treatment With Acetyl-L-Carnitine
• Cannabidiol in Youth Alcohol Use Disorder
• Does Oxytocin Alter Tolerance to or Motivation for Alcohol
• Dexamethasone to Target Stress and Immune System Mechanisms Underlying Alcohol Craving
• Bridging ED to Outpatient AUD Therapy With Naltrexone
• Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder
• Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant
• LGG Supplementation in Patients With AUD and ALD
• Cannabidiol for Reducing Drinking in Alcohol Use Disorder
• The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
• Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
• Human Laboratory Study of ASP8062 for Alcohol Use Disorder
• Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder
• In Hospital IM Naltrexone: A Pilot Study
• Naltrexone in AUD Reward Drinkers
• Study of DCR-AUD in Healthy Volunteers
• Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder
• Alcoholic Liver Disease and the Gut Microbiome
• Efficacy of Simvastatin in Alcoholic Liver Fibrosis
• A Study of NAC for AUD
• Neural and Hormonal Influences on Sex Differences in Risk for AUD
• Characterizing the Effects of Family History of Alcoholism on Alcohol Analgesia
• CBD for the Treatment of Alcohol Use Disorder
• Novel mGluR5 Modulator Effects on Alcohol Drinking and MRI Outcomes
• Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study
• ED Initiated Oral Naltrexone for AUD
• Prazosin for Alcohol Use Disorder
• Enhancing the Effects of Alcohol Treatment With Lamotrigine
• Role of BP1.3656 on Alcohol Responses
• Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility Study
• Evaluation of the Efficacy of Sodium Oxybate in the Long-term Maintenance of Abstinence in Alcoholic Patients
• Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
• Ketone Ester Intervention in Alcohol Use Disorder
• Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers
• CBT-I Augmentation of TOP for Sobriety and Insomnia in AUD
• Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine
• Inpatient Single Dose Interventions for Alcohol Use Disorder
• Sex Differences in Risk for Alcohol Abuse
• Effect of Endotoxin on Alcohol Consumption
• Oxytocin to Enhance Integrated Treatment for AUD and PTSD
• Open Label Pilot Study of Perampanel for the Treatment of Alcohol Use Disorder
• Vortioxetine for Treatment of Depressive Mood and Alcohol Use
• Medication Development for Protracted Abstinence in Alcoholism: CORT118335 Versus Placebo
• Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder
• Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation
• Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
• FAAH Availability in Psychiatric Disorders: A PET Study
• Laboratory Screening of Lorcaserin for Alcohol Use Disorder
• Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)
• Pregabalin Trial for the Treatment of Alcohol Use Disorder
• Development of a Selective ALDH2 Inhibitor to Treat AUD
• An Inflammatory Challenge Using Endotoxin
• Measuring the Neuroimmune Response to Alcohol
• A Novel Human Lab Model for Screening AUD Medications
• Riboflavin for Glutamate Reduction in Alcohol Withdrawal
• Medication Development in Alcoholism: Suvorexant Versus Placebo
• Probenecid as Medication for Alcohol Use Disorder
• Neuroimmune Dysfunction in Alcohol Use Disorder
• Cannabidiol (CBD) for the Treatment of Alcohol Withdrawal
• Varenicline and Bupropion for Alcohol Use Disorder
• Bristol Imperial MDMA in Alcoholism Study
• MAP4343 Treatment for Alcohol Use Disorder
• Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
• Alpha-1 Blockade for Alcohol Use Disorder (AUD)
• Clinical Outcome of a Patented Pharmaceutical Composition (KT-110) to Treat Alcohol Use Disorder While Avoiding Major Side Effects
• Study to Evaluate AD04 in Adults With Alcohol Use Disorder (AUD) and Selected Serotonin Transporter Polymorphisms
• Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy
• Feasibility of Emergency Department Initiated Extended-Release Naltrexone for the Treatment of Alcohol Use Disorder
• The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking
• Alcohol and Cigarette Craving During Oxytocin Treatment
• Brexpiprazole in Alcohol Use Disorder
• Effect of Allopregnanolone on Stress-induced Craving
• HLAB-002 of ANS-6637 for Alcohol Use Disorder
• Cannabidiol for Alcohol Use Disorder
• COMT Inhibition Among Individuals With Comorbid AUD/ADHD
• Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD)
• Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence
• Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder
• The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence
• Intranasal Oxytocin for the Treatment of Alcohol Use Disorder
• The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders
• Oxytocin on Approach Bias and Craving
• Effects of Pioglitazone on Stress Reactivity and Alcohol Craving (Pilot)
• Study of the Opioid Modulation of the Effect of Alcohol on the Dopaminergic Reward System
• Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD
• Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
• Pharmacogenomics and Pharmacometabolomics of Acamprosate Treatment Outcome
• Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders
• [C-11]PiB PET Imaging in Alcohol Use Disorders
• Impulsivity and Alcohol Response
• Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
• Addressing Heavy Alcohol Use Consumption With Kudzu
• N-Acetylcysteine for Adolescent Alcohol Use Disorder
• Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
• Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence
• The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers
• Oxytocin Treatment for Alcohol Use Disorders
• Investigation of the Efficacy of Acamprosate and Calcium in Comparison to Placebo as Validation of a Behavioural Test for Alcohol Dependence
• Oxytocin and Stress Response in Alcohol Use Disorder
• Ibudilast for the Treatment of Alcohol Use Disorder
• Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
• Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol
• Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse
• Exploration of Gemfibrozil as a Treatment for AUD
• Ibudilast and Withdrawal-Related Dysphoria
• Defining the Clinical Role of Topiramate in the Treatment of Alcohol Dependence in Australia
• Behavioral Alcohol Responses (BAR) Study
• Understanding Alcohol Reward in Social Context
• [C-11]NOP-1A and Alcohol Use Disorder
• Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment
• Modafinil for the Treatment of Alcohol Use Disorders
• Effect of GET73 on MRS Measures of Central Glutamate and GABA in Individuals With Alcohol Use Disorder
• Targeting Stress-Induced Alcohol Relapse Risk With Doxazosin XL
• Ibogaine in the Treatment of Alcoholism: a Randomized, Double-blind, Placebo-controlled, Escalating-dose, Phase 2 Trial
• Zonisamide Outpatient Study
• Metabotropic Glutamate Receptor-5 (mGlur5) Effects on Reward-Related fMRI-BOLD Activation in FHP and FHN
• Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
• Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography
• Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)
• Baclofen in Managing Acute Alcohol Withdrawal
• Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
• Allogeneic HUman Mesenchymal Stem Cell InfusioN Versus Placebo in Subjects With Alcohol Use Disorder and Major DepreSsion.
• Pregabalin as Treatment for Alcohol Use Disorder
• Effects of Cannabidiol in Alcohol Use Disorder
• Cannabidiol as a Treatment for AUD Comorbid With PTSD
• Minocycline for Alcohol Use Disorder
• Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence?
• Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics
• Influence of n-Acetylcysteine Maintenance on Alcohol Effects
• Medication Development for Opioid and Alcohol Abuse
• Topiramate and Prolonged Exposure
• Medication Development in Alcoholism: Apremilast Versus Placebo
• Buproprion for Binge Drinking
• Neuroendocrine Response to Oral Alcohol Administration
• A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)
• Memantine in Bipolar Patients With Alcoholism
• Human Laboratory Study of Varenicline for Alcohol Use Disorder
• Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects
• Topiramate Treatment of Alcohol Use Disorders in African Americans
• Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.
• Fish Oil vs. Placebo on Subjective Effects of Alcohol
• Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder
• INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers
• Testing Doxazosin to Treat Stress Mechanisms in Alcoholism
• Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)
• Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment
• Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control
• Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
• NAC for Treating Comorbid PTSD and SUD
• Oxytocin and Alcohol Withdrawal and Dependence
• Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
• Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action
• Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home
• Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD
• Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence.
• A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment
• N-acetylcysteine Treatment of Alcohol Use Disorder In Veterans With TBI
• PPARγ Agonist Treatment for Cocaine Dependence
• Treatment for Alcohol Dependence With Gabapentin
• Nalmefene in Alcohol Dependence and Borderline Personality Disorder
• Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
• Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users
• Neural Mechanisms of Disulfiram Effects
• Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU
• Oxytocin in Alcohol Use Disorder
• A Novel Compound for Alcoholism Treatment: A Translational Strategy
• Combining Varenicline and Naltrexone for Smoking Cessation
• Gut Hormones in Obesity, Nicotine and Alcohol Dependence
• Adaptive Treatment for Alcohol and Cocaine Dependence
• A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects
• Validation of a Test System for Development of Medications for Alcoholism
• Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II
• Ketamine for Reduction of Alcoholic Relapse
• Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
• Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder
• Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
• Glutamatergic Modulation of Disordered Alcohol Use
• A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
• Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems
• CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders
• Use of Selincro and Impact on Usual Practice
• CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders
• Alcohol Disorder hOsPital Treatment Trial
• The Effects of Oxytocin on Startle Hyperreactivity in Patients With AUD and PTSD
• Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
• Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
• Carisbamate as a Potential Treatment for Alcohol Dependence
• Laboratory Studies on Oxytocin for Treatment of Alcohol Use Disorder
• A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence
• Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity
• A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers
• Effectiveness of Zonisamide in Alcohol Dependent Veterans
• A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)
• Pharmacogenetic Study of Ondansetron in Alcohol Use Disorder
• Gabapentin for Alcohol Relapse Prevention
• Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
• Oxytocin Treatment of Alcohol Dependence
• The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism
• HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder
• Oxytocin Treatment of Alcohol Dependence
• Mifepristone for the Prevention of Relapses of Alcohol Drinking
• Impact of a One-month Long Detoxification Diazepam Treatment on Early Alcohol Relapse
• Brain Inflammation and Function in Alcoholism
• Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers With and Without PTSD
• Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence
• Pregabalin for Alcohol Dependence
• Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use
• Acute Effects of Cortisol on Alcohol Craving in Alcohol Dependence
• Varenicline + Prazosin for Heavy Drinking Smokers
• Progesterone Effect on Individuals Diagnoses With AD and PTSD.
• Minocycline's Effects on Alcohol Responses in Humans
• Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.
• Mifepristone Treatment of Alcohol Use Disorder
• A Study of ALKS 3831 in Subjects With Schizophrenia and Alcohol Use Disorder
• Medication Development in Alcoholism: Investigating PPAR Agonists
• Ketamine Alcohol (in Treatment-Resistant Depression)
• Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence
• Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome
• Ondansetron for Bipolar Disorder and Alcohol Use Disorders
• Citicoline for Alcohol Dependence
• A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence
• Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
• Development of Ivermectin for Alcohol Use Disorders
• A Novel Compound for Alcoholism Treatment
• Naltrexone for Individuals of East Asian Descent
• Development of Ibudilast for Alcohol Use Disorder
• Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
• Efficacy and Safety of High Dose Baclofen for Alcohol Dependence
• Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Followi
• Preventing Alcohol Withdrawal With Oral Baclofen
• Harm Reduction With Pharmacotherapy (HaRP)
• Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin
• Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
• Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence
• Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care
• Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence
• Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons
• Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence
• Safety and Pharmacodynamic Study of GET 73 in Alcohol Dependent
• A Study of LY2940094 in Participants With Alcohol Dependency
• Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers
• Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers
• Valproate for Mood Swings and Alcohol Use Following Head Injury
• Dutasteride Treatment for the Reduction of Heavy Drinking in Men
• Baclofen for Treating Anxiety and Alcoholism
• A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD
• To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK1521498 and Naltrexone on Physiological and Behavioural Markers of Brain Function in Healthy Social Drinkers
• Efficacy and Safety of Baclofen for Maintenance of Abstinence in Alcohol Dependent Patients
• Imaging of Cannabinoid 1 Receptors Using [11C]OMAR and PET
• Norepinephrine Transporter Imaging in Addiction Disorders
• Baclofen in the Treatment of Alcohol Dependence With or Without Alcoholic Liver Disease
• Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
• Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers
• Role of Proinflammatory Signaling in Alcohol Craving
• Safe and Effective Sedation in Chronic Alcoholic Patients Underwent Diagnostic Endoscopic Procedures: Study Comparing Midazolam and Propofol With Midazolam
• ABT-436 for Alcohol Dependence
• Baclofen for the Treatment of Alcohol Drinkers
• Pharmacogenetic Treatments for Alcoholism
• Functional Neuroimaging of Alcoholism Vulnerability (PIT)
• Zonisamide for Heavy Drinkers With Bipolar Disorder
• The Effects of Treatment With Naltrexone in Alcohol and Cannabis-dependent Patients
• Varenicline Treatment of Alcohol Dependence in Smokers
• Ketamine for Depression and Alcohol Dependence
• Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists
• Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence
• Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder
• A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease
• Doxazosin an a1 Antagonist for Alcohol Dependence
• Risperidone and Desipramine in Alcohol Use and Schizophrenia
• Topiramate for Alcohol Use in Posttraumatic Stress Disorder
• Naltrexone for Medication Compliance Among HIV-infected Men With Alcohol Use Disorder
• Genetics of the Acute Response to Alcohol in Social Drinkers
• GSK1521498 Alcohol Interaction Study
• Effect of JNJ 31001074 on Urge to Drink in Alcohol-Dependent Adults
• D-Cycloserine to Enhance Extinction to Alcohol Cues
• Varenicline Treatment for Active Alcoholic Smokers
• Treatment Strategy for Alcohol Use Disorders in Veterans With TBI
• Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake
• Vigabatrin for Cocaine and Alcohol Dependence
• Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.
• Effects of Sulfasalazine on BOLD Response to Alcohol Cues
• Sweet Preference and Alcohol Craving
• Aripiprazole Effects on Alcohol Drinking and Craving
• Varenicline in Drug Treatment
• Baclofen for the Treatment of Alcohol Dependence
• Dutasteride for the Reduction of Alcohol Use in Male Drinkers
• Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ Persons
• Will Having Alcohol Treatment Improve Functioning?
• A Study of Brain Receptor Occupancy in Healthy Subjects
• Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
• ALK21-006: Long-Term Study of Medisorb® Naltrexone (VIVITROL®)
• ALK21-003EXT: An Extension of Study ALK21-003 (NCT01218958) to Test the Long-term Safety of Medisorb® Naltrexone (VIVITROL®)
• ALK21-003: Study of Medisorb® Naltrexone (VIVITROL®) in Alcohol-Dependent Adults
• N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence
• Effects of Omegas 3 and 6 on Alcohol Dependence
• Paliperidone Palmitate Efficacy and Safety in Bipolar Disorder Complicated by Alcoholism
• Effects of Ghrelin on Alcohol Cue Reactivity and Craving
• CRF1 Antagonist GSK561679 in Alcoholism
• New Treatment for Alcohol and Nicotine Dependence
• Alcohol Interaction Study
• HBPL Study of the Impact of the NK1 Antagonist Aprepitant
• Varenicline and Alcohol in Inpatient Addictions Program (IAP)
• Effects of Levetiracetam (Keppra) on Alcohol Consumption
• A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency
• Pilot Study of Depot NTX in Homeless Veterans
• Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving
• Varenicline for Alcohol Dependence
• Efficacy of Topiramate for Hospitalized Patients With Alcoholism
• Gabapentin for Abstinence Initiation in Alcohol Dependence
• Topiramate for Hospitalized Patients With Alcoholism: a 12-week Study
• Medication and Counseling for Controlled Drinking
• Matching Genotypes and Serotonergic Medications for Alcoholism
• Neural Mechanisms Underlying Alcohol Induced Disinhibition
• Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy
• Alcohol Pharmacotherapy for HIV+ Prisoners
• A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking
• Varenicline for Alcohol Dependence
• Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
• Treatment of Alcohol Dependence and Comorbid Bipolar Disorder
• Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
• Baclofen to Reduce Alcohol Use in Veterans With HCV
• Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients
• Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
• ALK33-005: A Study of ALKS33 (RDC-0313) in Adults With Alcohol Dependence
• Levetiracetam XR in Very Heavy Drinkers
• Chicago Social Drinking Project
• Duloxetine Versus Pregabalin for Alcohol Dependence
• Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism
• Effects of GSK598809 on Brain Activation in Abstinent Alcoholics
• The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD
• Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults
• Aripiprazole and Topiramate on Free-Choice Alcohol Use
• Efficacy and Tolerability of Baclofen for Alcohol Dependence
• The Effects of Mirtazapine Versus Placebo on Alcohol Consumption in Male Alcohol High Consumers
• Effect of Varenicline on Reactivity to Smoking and Drinking Cues
• Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
• Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism
• Alcohol Detoxification in Primary Care Treatment (ADEPT)
• Puerarin Effects on Alcohol Drinking
• Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals?
• A Study of MK0594 in Patients With Alcohol Dependence (0594-020)
• Pharmacogenetic Response to Naltrexone For Alcohol Dependence
• Understanding Treatment Response With Naltrexone Among White Alcoholics
• Efficacy of Nalmefene in Patients With Alcohol Dependence
• Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence
• Efficacy of Nalmefene in Patients With Alcohol Dependence
• A Study in the Treatment of Alcohol Dependence.
• A Study for the Treatment of Alcohol Dependence
• Topiramate to Aid Smoking Cessation in Alcohol Dependent Men
• Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects
• ALK29-002: A Study of Baclofen Formulations in Healthy Adults
• ALK33-001: A Study of RDC-0313 Administered to Healthy Adults
• VIVITROL as a Treatment for Cocaine and Alcohol Dependence
• Combining Medications for the Treatment of Alcohol Dependence: An Inpatient Preliminary Study
• Combined Pharmacotherapies for Alcoholism
• Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants With Alcohol Dependence (P05718)
• Study of the Medication Prazosin for Alcohol Dependence
• Efficacy and Safety of Levetiracetam in Prevention of Alcohol Relapse in Recently Detoxified Alcohol Dependent Patients
• A New Pharmacotherapy for Alcohol Dependence: Olanzapine
• Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
• Pharmacogenetics of Alcohol: Treatment Implications
• Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia
• Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety Disorder
• Varenicline (Chantix™) for the Treatment of Alcohol Dependence
• Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function
• GABRA2 and the Pharmacokinetics of Risk for Alcoholism (GPRA)
• High Dose Vitamin B1 to Reduce Abusive Alcohol Use
• Ondansetron With Olanzapine for the Treatment of Alcohol Dependence: A Preliminary Clinical Trial
• Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia
• Seroquel for Frequent, Heavy Drinkers
• An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence
• The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion
• Acamprosate: Genes Associated With Response
• Medication Development in Alcoholism: Acamprosate Versus Naltrexone
• Safety of Acamprosate for Alcohol Dependence in the Elderly: An Open-Label Study (SAFADIE)
• Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects
• Cannabinoid Receptor Function & Alcoholism
• Extended-release Naltrexone for Alcohol Dependence in Primary Care
• Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study.
• Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
• GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
• Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics
• Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
• Ketamine/Placebo Family History Positive Study
• Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse
• Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
• The Use of Anticonvulsants for Treatment of Patients With Alcohol Dependence and Post Traumatic Stress Disorder
• Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence
• Naltrexone for Heavy Drinking in Young Adults
• N-acetylcysteine in Alcohol Dependence
• Mecamylamine for the Treatment of Patients With Depression and Alcohol Dependence
• Quetiapine vs. Placebo in Alcohol Relapse Prevention - a Pilot Study
• Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults
• Research on Individualized Treatment for Alcoholism
• ALK21-018: Effects of Medisorb® Naltrexone (VIVITROL®) on Alcohol Craving in Treatment-seeking, Alcohol-dependent Adults
• ALK21-014: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) After Enforced Abstinence
• Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency
• Effects of Alcohol on Simulated Driving
• Acamprosate vs. Placebo in Bipolar Alcoholics
• Topiramate for Treatment of Patients With Borderline Personality Disorder and Alcohol Dependence
• Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism
• Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
• Quetiapine for Bipolar Disorder and Alcohol Dependence
• Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI)
• Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI)
• Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
• Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism
• Novel Pharmacotherapy for Dual Dependence
• Medication and Counseling for Controlled Drinking (Project SMART)
• Substance Abuse Pre-Treatment Screening Study
• Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence (ALC-DRD2-APO)
• Comparative Trial Of Disulfiram, Naltrexone And Acamprosate In The Treatment Of Alcohol Dependence
• The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence
• Antabuse in Severe Alcoholism: an Open Controlled Study
• Study of Acamprosate in Driving Under the Influence (DUI) Court Participants
• The Effects of Zonisamide on Alcohol Dependence
• Alcohol Self Administration Laboratory
• Gabapentin Treatment of Alcohol Dependence
• Pharmacological Treatment for Alcoholism
• Study of Campral (Acamprosate) for Alcohol Dependence in a Family Medicine Clinic
• STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse
• Targeted Naltrexone for Problem Drinkers
• Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism.
• Sertraline Pharmacotherapy for Alcoholism Subtypes
• Effectiveness of Naltrexone Versus Placebo to Reduce Craving for Alcohol With Evaluation of Genetic Variability.
• Acamprosate Initiated During Alcohol Detoxification
• Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety
• Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients
• Naltrexone & SSRI in Alcoholics With Depression/PTSD
• Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism
• Open Label Trial of Acamprosate in Bipolar Alcoholics
• Acamprosate in Alcoholics With Comorbid Anxiety or Depression
• The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects
• Naltrexone in the Treatment of Concurrent Alcohol Dependence and Pathological Gambling
• The Effects of Levetiracetam on Alcohol Dependent Subjects
• Individually Adapted Therapy of Alcoholism
• Effect of LY686017 on Alcohol Craving
• Optimizing Pharmacotherapy for Bipolar Alcoholics
• Topiramate for the Treatment of Alcohol Dependent Binge-Eating Disordered Individuals
• Prometa Protocol for Alcohol Dependence
• Combined Treatment for Alcohol-Dependent Individuals With PTSD
• Treatment of Patients With Alcoholism and Attention Deficit Disorder
• Effectiveness of Sertraline in Treating Pathological Gamblers With a Diagnosis of Alcohol Dependence - 1
• Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI)
• Study of Acamprosate to Prevent Alcohol Relapse in Criminal Justice Supervisees
• Psychosocial and Medication Treatment for Anxiety in Alcoholism
• Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism
• A Placebo-Controlled Trial of Memantine for Alcohol Dependence
• Prazosin for ETOH or Cocaine Craving
• Alcohol and Gender Effects on Stress Circuit Function
• Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics
• New Medications to Treat Alcohol Dependence
• Naltrexone for Bipolar Disorder and Alcohol Dependence
• Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
• An Evaluation of Divalproex vs. Olanzapine for Alcohol Abuse Relapse Prevention in Patients With Bipolar Disorder
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1
• Combined Treatment for Cocaine-Alcohol Dependence - 1
• An Efficacy and Safety Study of Topiramate in the Treatment of Alcohol Dependence
• Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence
• Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms
• Clinical Trial With Ziprasidone for the Treatment of Psychiatric Pathology Associated to Alcoholism
• Atomoxetine Treatment of Adults With ADHD and Comorbid Alcohol Abuse
• Aripiprazole Effects on Alcohol Reactivity and Consumption
• Effectiveness of Naltrexone and/or Ondansetron to Reduce Craving for Alcohol and Drinking
• Effectiveness of Gabapentin When Used With Naltrexone to Treat Alcohol Dependence Compared to Placebo and Naltrexone Alone
• Alcoholism and Schizophrenia: Effects of Clozapine
• Prazosin Alcohol Dependence IVR Study
• Topiramate for Alcohol and Cocaine Dependence
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence
• Integrative Therapy in Alcoholism
• ALK21-006EXT: Long-term Safety of Medisorb® Naltrexone (VIVITROL®) in Alcohol- or Opioid-dependent Adults (Extension of Study ALK21-006 [NCT01218997])
• ALK21-010: Long-term Safety of Medisorb® Naltrexone (VIVITROL®) in Alcohol-dependent Adults
• Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder
• Improving Hepatitis C Treatment in Injection Drug Users
• Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects.
• Naltrexone Treatment of Alcohol Abuse in Schizophrenia
• Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1
• Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence
• Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
• Outpatient Treatment of Alcohol Withdrawal Syndrome
• Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder
• Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.
• Trial for the Treatment of Alcohol Dependence
• Managing Alcoholism in People Who Do Not Respond to Naltrexone
• Efficacy and Safety of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Alcohol Dependency in Patients With Bipolar Disorder
• Acamprosate to Reduce Symptoms of Alcohol Withdrawal
• Study of Aripiprazole in Subjects With Alcoholism
• Combination Nicotine Replacement for Alcoholic Smokers
• Bupropion as a Smoking Cessation Aid in Alcoholics
• Pharmacological Intervention Project (Fluoxetine)
• Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)
• Trazodone for Sleep Disturbance in Early Alcohol Recovery
• Treating Alcohol Use In Older Adults With Depression
• Serotonin in Alcoholism
• Comparing Gabapentin and Lorazepam for Treating Alcohol Withdrawal
• Preliminary Human Trial of NPI-028
• Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)
• Post-Treatment Effects of Naltrexone
• COMBINE (Acamprosate/Naltrexone)
• Alcohol Dependency Study: Combining Medication Treatment for Alcoholism
• Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
• Naltrexone, Craving, and Drinking
• Sertraline for Alcohol Dependence and Depression
• Acamprosate Treatment: Mechanisms of Action
• Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch)
• Sertraline and Cognitive Therapy in Depressed Alcoholics
• Pharmacologic Relapse Prevention for Alcoholic Smokers
• Behavioral Therapy Plus Naltrexone for Alcoholism
• Naltrexone for Early Problem Drinkers
• Smoking Cessation in Alcoholism Treatment
• Naltrexone Treatment of Alcohol Dependence
• Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)
• Naltrexone Maintenance Treatment of Alcoholism
• Behavior and Naltrexone Treatment for Alcoholics
• Naltrexone Treatment for Alcoholic Women
• Behavioral/Drug Therapy for Alcohol-Nicotine Dependence (Naltrexone/Nicotine Patch)
• Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder
• Use of Naltrexone in a Clinical Setting
• Timing of Smoking Intervention in Alcohol Treatment (Nicotine Patch)
• Ondansetron Treatment for Alcoholism
• Naltrexone for Relapse Prevention
• Drug Therapy for Alcohol Detoxification
• Sertraline and Naltrexone for Alcohol Dependence
• Drug Treatment for Alcoholics With Bipolar Disorder
• Naltrexone Treatment for Alcoholism
• Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)
• Disulfiram for Cocaine-Alcohol Abuse - 3