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Clinical Trials for Prediabetic State

• Dexamethasone/Pancreatic Clamp P&F
• Effect of Metformin on Healthy Live Birth in Women With Prediabetes
• Assessing the Effects of HbA1c Reduction on Alleviating Nonspecific Back Pain
• SGLT2 Inhibition in Addition to Lifestyle Intervention and Risk for Complications in Subtypes of Patients With Prediabetes
• Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β
• Zinc Supplementation in Prediabetes
• A Study to Evaluate Efficacy and Safety of Distal Jejunal-release Dextrose Beads Formulation (APHD-012) in Subjects With a Pathological Oral Glucose Tolerance Test (OGTT)
• Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
• Dinner Time for Obesity and Prediabetes
• Glycemic Effect of Diazoxide in NAFLD
• Pancreatic Clamp in NAFLD
• Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes Mellitus
• The SLIM LIVER Study
• ADRB3 Signaling Pathway in Human Adipose Tissue
• HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes
• Efficacy of Suvorexant in the Treatment of Insomnia in Midlife Women With Pre-Diabetes
• Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE DM)
• Use of Empagliflozin to Treat Prediabetes
• Genetics of the Acute Response to Oral Semaglutide (GAROS)
• Linagliptin Response to OGTT in Prediabetes and Type 2 Diabetes Mellitus
• Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes
• Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes
• Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)
• Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes
• Intervention Effect of Canagliflozin on Prediabetes in Patients With HIV: A Randomized Controlled Trial.
• Tangningtongluo Tablet for People With Prediabetes
• Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
• Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans
• Liraglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease
• The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics
• Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
• SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot
• Treatment to Regress to Normoglycemia in Women With a Recent History of GDM
• Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus
• An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
• Mechanisms for Activation of Beige Adipose Tissue in Humans
• Identification of Biometric Marker(s) Capable of Detecting Early Prediabetes: Clinical Trial 1
• Obesity and Uric Acid Stones Study
• The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes
• NBT-NM108 as an Early Treatment for Suspected or Confirmed Symptomatic COVID-19 Patients
• Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes
• eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk
• SGLT2 Inhibition in Older Obese Adults With Pre-diabetes
• Developing an Obesity Treatment Program in Family Medicine Clinics
• Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
• Effects of dapaglifloziN Therapy on Myocardial Perfusion Reserve in Prediabetic Patients With Stable coronarY Artery Disease
• Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons
• Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes
• Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes
• Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine
• Effectiveness of Dapagliflozin for Weight Loss
• Assess the Efficacy and Safety of Exenatide SR for the Prevention of Diabetes After Kidney Transplantation
• The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans
• Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes
• Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes
• Can the Health Benefits of a Walking-based Exercise Programme be Enhanced by Co-ingestion of a Lipid-lowering Drug?
• Metformin and Systemic Inflammation in HIV
• Effects of 2 Weeks Treatment With Dapagliflozin in Subjects With an Impaired Glucose Homeostasis on Nocturnal Substrate Oxidation
• Ciprofibrate and Pre-diabetes
• Effect of Dapagliflozin on the Progression From Prediabetes to T2DM in Subjects With Myocardial Infarction
• Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes
• China Protection Trial of Glucose Metabolism by Pitavastatin in Patients With Prediabetes and Hypertension
• Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition
• The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program
• Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients
• Soluble Epoxide Hydrolase Inhibition and Insulin Resistance
• Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
• High-Dose Statin Combined With Telmisartan vs Amlodipine on Glucose Metabolism in ASCVD Patients With IFG and Hypertension
• Efficacy of Metformin in Preventing Diabetes in China
• Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.
• Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind.
• Walnuts to Achieve Lasting NUTrition to Prevent Diabetes
• A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes
• Once Weekly GLP-1 in Persons With Spinal Cord Injury
• Effect of Empagliflozin Versus Placebo on Brain Insulin Sensitivity in Patients With Prediabetes
• Prevention of Microvascular Complications in Prediabetes e-PREDICE Study
• PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment
• Cardiovascular Effects of GLP-1 Receptor Activation
• Dapagliflozin in PRESERVED Ejection Fraction Heart Failure
• Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes
• Effect of Dapagliflozin on Blood Pressure Variability in Prediabetes and Prehypertension
• Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes
• Hospital-based Diabetes Prevention Study in Korea
• Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
• Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
• Autoimmune Diabetes Accelerator Prevention Trial
• The Effect of Acute Lysine Administration on α-aminoadipic Acid
• Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes
• Coronary Artery Disease Progression in Patients With Prediabetes
• Interventional Bioremediation of Microbiota in Metabolic Syndrome
• Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes
• The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes
• Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo
• Effect of Melatonin on Cardiometabolic Risk- FULL
• Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)
• Effects of Melatonin Supplementation on Renal Physiology in a Habitual Sleep Restricted Population.
• Cold Induced Changes in White Adipose
• Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin
• BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)
• The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients
• Improving Beta Cell Function in Mexican American Women With Prediabetes
• Effect of Atorvastatin on Glycemic Control in Prediabetic Patients
• Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
• Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
• BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes
• ORION: Effects of Cenicriviroc on Insulin Sensitivity in Subjects With Prediabetes or Type 2 Diabetes Mellitus (T2DM) and Suspected NAFLD
• Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin
• The Effect of Liraglutide in Patients With Prediabetes and Kidney Failure
• Metformin to Augment Low Milk Supply (MALMS) Study
• Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness
• Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes
• Effects of Antidiabetic Medications on the Postprandial State in Prediabetes
• Exenatide and Weight Loss for Diabetes Prevention
• Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment
• Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis
• Effect of Allopurinol Treatment on Insulin Resistance
• Beneficial Effect of Salicylates: Insulin Action, Secretion or Clearance?
• Inflammation Inhibition in Prediabetic Humans
• Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
• Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity
• Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
• The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion
• ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes)
• Sleep Effectiveness and Insulin and Glucose Homeostasis
• Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)
• Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
• Metformin and Muscle in Insulin-resistant Older Veterans
• Liraglutide and a Calorie Restricted Diet Augments Weight Loss and Decreases Risk of Type 2 Diabetes and CVD.
• RISE Pediatric Medication Study
• RISE Adult Medication Study
• Metformin and Longevity Genes in Prediabetes
• Beta Cell Restoration Through Fat Mitigation
• The Effects of RVX000222 on Glucose Metabolism in Individuals With Pre-diabetes
• A Pilot Study to Determine the Effect of a Cobiotic Formulation on the Gastrointestinal Microbiome
• Role of Rosiglitazone on Pre-Diabetes Mellitus and Coronary Artery Disease
• A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
• Efficacy and Safety of DLBS3233 in Prediabetic Patients
• Effects of Vitamin D on Beta Cell Function and Insulin Sensitivity in Pre-diabetes and Diabetes Mellitus Type 2
• Bioavailability and Biological Effects of Vitamin D2 Contained in Mushroom
• Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy
• Oral Cholecalciferol in Prevention of Type 2 Diabetes Mellitus
• Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
• Effect of Dietary Glycemic Index on Beta-cell Function
• Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
• Glucose Control in Pre-Diabetic Renal Transplant Patients
• Metformin and Sitagliptin in Women With Previous Gestational Diabetes
• Reducing Risk of Type 2 Diabetes: Hydroxychloroquine Use in Pre-Diabetes
• Cinnamon Trial-lIfestyle iNtervention Plus Water-soluble Cinnamon Extract On loweriNg Blood Glucose in Pre-diabetics
• Study TO Prevent Diabetes With Short-term Insulin Glargine Only
• Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes
• The Effect of Aliskiren on Endothelial Function in Pre-Diabetes and Diabetes
• Effective Treatment of Sleep Apnea in Prediabetes to Reduce Cardiometabolic Risk
• Diabetes Prevention - Immune Tolerance
• Effect of Simvastatin and Ezetimibe on Lipid and Inflammation
• The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion
• Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance
• DPP-4 Inhibition and TZD for DM Prevention
• Safety & Effectiveness on Vascular Structure and Function of ACZ885 in Atherosclerosis and Either T2DM or IGT Patients
• Study to Evaluate the Effects of Colesevelam on Insulin Sensitivity and ß-Cell Function in Subjects With Impaired Fasting Glucose (Prediabetes)
• Prevention of Cystic Fibrosis Diabetes
• The Effect of Vitamin K Supplementation on Glucose Metabolism
• Vitamin D in Minorities With Prediabetes
• The Effects of Exenatide on Post-Meal Sugar Peaks and Vascular Health in Obese/Pre-Diabetic Young Adults
• Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls
• A Study for Pre-diabetic Patients With Cholesterol Lowering Drugs
• Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
• Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis
• Physical Exercise Versus Rosiglitazone in CAD and Prediabetes
• Mechanisms Underlying Metabolic Syndrome in Obesity
• Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.
• Effects of PPAR Ligands on Ectopic Fat Accumulation and Inflammation
• Atheroma Reduction With Chloroquine in Patients With the Metabolic Syndrome (ARCH-MS)
• Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS)
• Treating the Endothelium to Restore Insulin Sensitivity
• Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects
• Incretins in Impaired Fasting Glucose
• Rimonabant In Prediabetic Subjects To Delay Onset Of Type 2 Diabetes
• A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes
• Efficacy and Safety of Vildagliptin in Subjects With Impaired Glucose Tolerance
• Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome
• Chromium Picolinate for the Treatment of Metabolic Syndrome
• Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance