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Clinical Trials for Hyperalgesia

• Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
• The Effect of Remimazolam on Opioid Induced Hyperalgesia
• STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
• Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery
• Safety and Efficacy Evaluation of S (+) - Ketamine in Children
• Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans
• Repeated Cannabis Administration on Experimental Pain and Abuse Liability
• Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults
• Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy Adults
• Effect of Cannabinoid (THC / CBD 50%) on Hyperalgesia in Patients With Deep Endometriosis
• Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl
• Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) Model
• Gabapentin Pretreatment for Staged Bilateral Cataract Operations
• Investigation of the Strategy of Preventing Post-operative Opioid-induced Hyperalgesia
• Can DFN-15 Terminate Migraine With Allodynia?
• Interaction Between NGF and Acute Exercise-induced Ischemia
• Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
• Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity
• Prevention of Hyperalgesia With Epidural Morphine
• Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
• Low-Dose Naltrexone and Acetaminophen Combination in the Treatment of Chronic Low Back Pain (ANODYNE-4)
• Remifentanil and Hyperalgesia: Gradual Withdrawal Versus Immediate Discontinuation
• Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia
• Effect of High-dose Naloxone Following Third Molar Extraction
• Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol
• An fMRI Study in Healthy Volunteers to Investigate the Effects of ABX-1431 on Experimental Hyperalgesia and Its Neural Correlates
• The Effect of Ultra-low-dose Naloxone on Remifentanil-induced Postoperative Hyperalgesia - A Randomized Controlled Study
• A Trial of Lidocaine Patch for Lower Limb Amputation Pain
• Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent
• Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury
• Dextromethorphan Effect on Central Sensitization to Pain in Healthy Volunteers
• The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury Model
• Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
• The Efficacy of MK-8291 in Participants With Post-herpetic Neuralgia (PHN) With Allodynia (MK-8291-012)
• A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients
• Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
• Can Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?
• Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial
• Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)
• Effect of Gabapentin on Pain of the Second Cataract Surgery
• Hyperalgesia and NMDA Receptor Antagonist
• Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients
• Hyperbaric Oxygen Therapy Attenuates Central Sensitization Induced by a Thermal Injury in Human Volunteers (HBO)
• Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.
• Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers
• Effect of High Dose Naloxone on Secondary Hyperalgesia
• Analgesic Effect of Oxytocin Receptor Modulation
• Botulinum Toxin Type A for Treating Allodynic Pain in SCI and MS
• Mechanisms of Sleep Disruption Hyperalgesia
• Effect of Nefopam on Remifentanil Induced Postoperative Hyperalgesia
• Opioid-induced Hyperalgesia After Remifentanil Infusion
• Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance
• Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models
• Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
• Hyperalgesia and Pain
• IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery
• Preventing Pain After Heart Surgery
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical Trial
• Botulinum Toxin Type A in Treatment of Cranial Allodynia in Patients With Headache
• Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia
• Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia
• Effects of Milnacipran on Widespread Mechanical and Thermal Hyperalgesia of Fibromyalgia Patients
• Prevention of Persistent Postsurgical Pain After Thoracotomy
• Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
• Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?
• Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery
• Efficacy of Etoricoxib on Peripheral Hyperalgesia
• Local Anesthetic Continuous Preperitoneal Infiltration and Wound Hyperalgesia
• Effect of Intraoperative Magnesium on Remifentanil-induced Postoperative Hyperalgesia After Thyroidectomy
• Transversus Abdominis Plane (TAP) Block for Cesarean Section
• The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)
• Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil
• Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects
• Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis
• Effect of Systemic Ropivacaine on Hyperalgesia, Flare Reaction and Peripheral Nerve Excitability
• The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers
• Lactobacillus Farciminis and Hyperalgesia
• Effect of Ketamine on Opioid-Induced Hyperalgesia
• A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers
• Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery
• Subcutaneous Botulinum Toxin for Cutaneous Allodynia - Enriched Responder Trial
• The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
• Local Anesthetic Infusion and Sternotomy
• The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers
• Modulation of Remifentanil-induced Postinfusion Hyperalgesia
• Subcutaneous Botulinum Toxin for Cutaneous Allodynia
• A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.
• A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia
• Pain Medicine for Wound Care Procedures
• The Effect of Intravenous Lidocaine on Allodynia
• Sensory Function After Wound Instillation of Capsaicin
• Fentanyl Ultra Low Doses Effects on the Nociceptive Threshold
• Epidural Clonidine for Postoperative Hyperalgesia
• Effects of Nefopam on Hyperalgesia After Cardiac Surgery
• A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
• Effects of Lidocaine Patch on Intradermal Capsaicin Induced Pain and Hyperalgesia
• Hyperalgesia in Methadone Patients: Can it be Treated?
• Effects of Pregabalin on Mechanical Hyperalgesia
• Polyamine-free Diet to Prevent Post Surgery Hyperalgesia
• GW406381 In Patients With Peripheral Nerve Injury
• Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers
• Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
• Analgesic Efficacy of Smoked Cannabis
• Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia
• Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia, Opioid Use, and Pain After Radical Prostatectomy
• Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?
• Positron Emission Tomography to Measure Pain and Pain Control