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Clinical Trials for Substance-Related Disorders

• Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
• Oral Buprenorphine as a Novel Low-dose Induction Strategy for Opioid Use Disorder
• Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder
• Multiple Ascending Dose Study of TMP-301 in Healthy Subjects
• Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder
• Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy
• Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
• Transdermal Rotigotine as Adjunct to Behavioral Therapy for Cocaine Use Disorder
• Age-dependent Effects of Smoked and Oral Delta-9-THC
• Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
• Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3
• Cannabis and Opioid Use Disorder
• E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
• Effect of Folic Acid on the Presentation of Nuclear Abnormalities in People With a History Drug Abuse
• OMAR Opioid Use Disorder
• Orexin's Role in The Neurobiology of Substance Use Disorder
• Open Label Comparison of Injectable Buprenorphine ( Brixadi®) and Naltrexone (Vivitrol®) for Opioid Use Disorder
• Defining Neurobiological Links Between Substance Use and Mental Illness
• Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use
• Smoking Cessation and Menstrual Cycle Phase: A Randomized Controlled Trial
• Abuse Potential and Human Pharmacology of Methylone
• Low-dose Buprenorphine Initiation of Opioid Use Disorder
• SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
• Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder
• Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco
• Study of LYN-014 in Individuals With Opioid Use Disorder Who Are Stable on Methadone Therapy
• Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use
• Postpartum MDMA Co-occurring PTSD and OUD
• KAP for Depression in Abstinent Opioid Users
• Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)
• Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization
• Evaluation of Oral THC and CBD in Men and Women
• A Study to Assess the Safety and Efficacy of ASP8062 as an Add-on Therapy to Buprenorphine/Naloxone in Participants With Opioid Use Disorder
• Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder
• Evaluation of Smoked THC and CBD in Men and Women
• Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
• Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users
• Opioid Use Disorder Treatment Linkage at Sexual Health Clinics Using Buprenorphine
• Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder
• The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder
• Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder
• The Effect of Micro-doses Erytropoietin on Exercise Capacity in Male and Females
• Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
• AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)
• Computerized Chemosensory-Based Orbitofrontal Cortex (CBOT) for Opioid Use Disorder
• Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition
• Young Houston Emergency Opioid Engagement System
• PrEP at a Syringe Services Program
• Feasibility of Pediatric Emergency Department-Initiated Treatment for Adolescents With Opioid Use Disorder
• Pharmacokinetic Study of Vivitrol in Healthy Participants
• Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections
• N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use
• Evaluating the Abuse Potential of Neurontin® When Taken Orally in Healthy Non-drug Dependent Participants With Sedative Drug Abuse Experience
• Neuroimaging and CBD for Heroin Use Disorder
• Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders
• Psychotherapy for Psychosis, Adverse Events, and Substance Misuse
• Providing Suboxone and PrEP Using Telemedicine
• Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
• Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
• Analgesic and Subjective Effects of Terpenes
• A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using Participants
• A Study to Assess the Effect of a Single Dose of ASP8062 on the Multiple Dose Safety, Tolerability and Pharmacokinetics of Buprenorphine/Naloxone in Participants With Opioid Use Disorder
• Can Anti-asthmatic Medication Improve Sprint Performance in Healthy Endurance Athletes?
• Cannabis Effects as a Function of Sex (CanSex)
• A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
• Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder
• EXHIT ENTRE Comparative Effectiveness Trial
• ANCHORS Alcohol & Sexual Health Study: UH3 Project
• Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder
• Dual-Orexin Antagonism as a Mechanism for Improving Sleep and Drug Abstinence in Opioid Use Disorder
• Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder
• Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
• A Single Ascending Dose Trial of CVL-936 in Healthy Subjects
• Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder
• Neuroimmune Dysfunction in Alcohol Use Disorder
• Cannabidiol Use to Reduce Cravings in Individuals With Opioid Use Disorder on Buprenorphine
• Ketamine for the Treatment of Opioid Use Disorder and Depression
• Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder
• Safety and Preliminary Efficacy of ANS-6637 to Reduce Drug Craving and Harm in People With Opioid Use Disorder
• Adjunctive Effects of Psilocybin and Buprenorphine
• Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users
• Benzodiazepine Discontinuation in Opioid Agonist Therapy
• Feasibility of Emergency Department Initiated Extended-Release Naltrexone for the Treatment of Alcohol Use Disorder
• A Prospective, Randomized Trial of the Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms
• SUBLOCADE Rapid Initiation Extension Study
• Lofexidine for Management of Opioid Withdrawal With XR-NTX Treatment
• Oxytocin, Stress, Craving, Opioid Use Disorder
• A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers
• Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
• Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE
• Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid
• Guanfacine to Improve Substance Use Outcomes in Women
• Neurobehavioral Mechanisms of Choice in Opioid Use Disorder
• Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder
• Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults
• PWID; Longitudinal S Aureus Colonization Pattern and the Impact on Infection Frequency by Regular Showers With Chlorhexidine
• Alcohol, Behavior, and Brain Imaging
• Intravenous Lidocaine for Perioperative and Postoperative Analgesia
• Medication Treatment for Opioid Use Disorder in Expectant Mothers
• Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study
• Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study
• Combination of GT90001 and Nivolumab in Patients With Metastatic Hepatocellular Carcinoma(HCC)
• An Open-Label Pilot Study of Sublocade as Treatment for Opiate Use Disorder
• Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder
• Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use
• Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence
• Reducing the Abuse of Opioids in Drug Users
• Cannabidiol as Adjunctive Treatment for Opioid Use Disorder
• A Comparison of How Likely it is That Different Tablets of Oxycodone Will be Broken up and Snorted by Adults Who Sometimes Take Drugs for Pleasure
• A Trial to Evaluate the Abuse Potential of 3 Doses of GRT6005 in Adult Non-dependent Recreational Opioid Users
• An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
• Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia
• Influence of Medication on Functional Connectivity
• HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)
• Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy
• Brexpiprazole Study
• Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital
• Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)
• Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients
• The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial
• Opioid Free Anesthesia vs. Opioid Anesthesia Techniques.
• Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
• Gabapentin for Bipolar & Cannabis Use Disorders
• A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users
• Evaluation of Erythroferrone as a New Biomarker of Erythropoesis Stimulating Agents
• Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075
• Pharmacogenetics of Naltrexone for Stimulant Abuse
• Brain Imaging of Cannabinoid Receptors
• Lorcaserin in Combination With XR-Naltrexone for Relapse Prevention in Opioid Use Disorder
• Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users
• Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
• Methylphenidate for Cocaine Dependence
• Interactions Between Drug Effects and Environments II
• Entolimod, an Adjuvant for Vaccine Augmentation
• Sofosbuvir/Velpatasvir in Postpartum Women With Opioid Use Disorder and Chronic Hepatitis C Infection
• Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting
• Lorcaserin in the Treatment of Cocaine Use Disorder
• Abuse Liability of Reduced Nicotine Content Cigarettes Within a Complex Tobacco Marketplace
• A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses
• NAC for Treating Comorbid PTSD and SUD
• Oxytocin and Alcohol Withdrawal and Dependence
• Cannabidiol and Emotional Stimuli
• Varenicline Treatment for Cannabis Use Disorder
• Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology
• Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation
• Imaging the Neurochemistry of Drug Addiction With PET
• DOX as a Potential Treatment for Methamphetamine Dependence
• Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
• Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain
• Stopping Benzodiazepines and Related Molecules Among Elderly Living in Residential Institutions
• Evaluating Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Transitioning From Buprenorphine Maintenance Prior to First Dose of VIVITROL
• Adaptive Treatment for Alcohol and Cocaine Dependence
• Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users
• Long-Term Safety Study of Buprenorphine (CAM2038) in Adult Outpatients With Opioid Use Disorder
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
• CDP-choline Treatment in ATS Users
• Observational Study of Preoperative Screen for Substance Abuse
• A Study to Evaluate Abuse Potential of Istradefylline
• Medication-Assisted Treatment for Youth With Substance Use Disorders
• Project BEST: Buprenorphine Entry Into Substance Abuse Treatment
• Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder
• Cannabidiol and Cocaine Craving/Dependence
• Improving Treatment Outcomes for Prescription Opioid Dependence
• Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder
• Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension)
• Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder
• Intervention for Teens With ADHD and Substance Use
• Effects of Expectation, Medication and Placebo on Objective and Self-rated Performance
• Carisbamate as a Potential Treatment for Alcohol Dependence
• Abuse Liability of Pregabalin and Its Effects on Benzodiazepine Withdrawal Symptoms
• Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia
• The TAP Study: Treating People Who Inject Drugs in Community-Based Settings Using a Social Network Approach
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
• Acquisition of Responses to a Methamphetamine-associated Cue in Healthy Humans
• A Randomized Double-Blind Controlled Trial of Creatine in Female Methamphetamine Users
• Open-Label Creatine Study for Female Meth Users
• Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence
• Abuse Liability of Controlled-Release Oxycodone Formulations
• A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users
• Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
• Adherence to HIV Therapy in Heroin Addicts: Oral vs XR-NTX
• Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence
• Study of Icariin for Bipolar Disorder and Co-Occurring Substance Use Disorders
• Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
• Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts.
• Buprenorphine to Improve HIV Care Engagement and Outcomes
• Effects of MDMA on Social and Emotional Processing
• Extended Release Naltrexone for Opioid-Dependent Youth
• Influence of Bupropion on the Effects of MDMA
• Methadone Oxytocin Option
• The Role of Sleep in the Treatment of Cannabis Use Disorders
• Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed Veterans
• Pramipexole as a Treatment for Cocaine Dependence
• A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence
• Memory Reconsolidation Blockade for Treating Drug Addiction
• Modafinil - Escitalopram Study for Cocaine Dependence
• RTI-336 as a Treatment for Methamphetamine Dependence
• A Study to Assess the Abuse Potential of Hydrocodone Extended-Release Tablet in Recreational Opioid Users
• Varenicline as a Treatment for Methamphetamine Dependence
• Pre-Release VIVITROL for Opioid Dependent Inmates
• Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution
• HIV, Buprenorphine, and the Criminal Justice System
• Risk of Shopping Behavior of Tapentadol Immediate-Release (IR) Compared to Oxycodone Immediate-Release (IR)
• Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)
• Creatine as a Treatment Option for Depression in Methamphetamine Using Females
• Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214
• Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)
• Varenicline for Methamphetamine Dependence
• Identification of New Serum Markers for Detection of Abuse With Erythropoietin
• Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment
• Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)
• Efficacy Of Bupropion For Attention Deficit Hyperactivity Disorder (ADHD) In Adults
• Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populations
• Safety Interaction Trial Ibudilast and Methamphetamine
• Efficacy of Atomoxetine for ADHD in Adolescents and Young Adults With SUD
• Psychopharmacotherapy in Multiple Substances Abuse
• Medications Development for Drug Abuse Disorders
• Effects of Levetiracetam (Keppra) on Alcohol Consumption
• Neurobiology and Pharmacokinets of Acute MDMA Administration
• Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray
• Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)
• Adherence to HIV Therapy in Heroin Addicts: Oral vs XR-NTX
• Rivastigmine as a Treatment for Methamphetamine Dependence
• Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis
• Drug Discrimination in Methadone-Maintained Humans Study 3
• NAC as a Potential Treatment for Methamphetamine Dependence
• The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine
• An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence
• Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults
• Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement
• GSK618334 Repeat Dose Study
• Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers
• Adaptive Treatment for Alcohol and Cocaine Dependence
• Rivastigmine and Huperzine A as Treatments for Cocaine Dependence
• Smoking Cessation Treatment for Methadone Maintenance Patients
• A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence
• Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
• Functional Magnetic Resonance Imaging of Opioid Withdrawal in Healthy Human Volunteers
• Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)
• Oxytocin and Cognitive Behavioral Therapy in Drug Dependence
• Atomoxetine/Attention Deficit/ Hyperactive Disorder (ADHD)/Substance Use Disorder (SUD)in a Residential Treatment Facility
• Relapse Prevention With Varenicline
• Bupropion for ADHD in Adolescents With Substance Use Disorder
• Effects of GSK598809 on Brain Activation in Abstinent Alcoholics
• Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)
• EtOH Interaction Study
• Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)
• Disulfiram Interactions With HIV Medications: Clinical Implications
• Study of Medical Treatment for Methamphetamine Addiction
• Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users
• An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand
• Contingency Management for Smoking in Substance Abusers
• Relapse Prevention Study in Newly Abstinent Smokers
• Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse
• Varenicline-Methamphetamine Interaction Study (2008)
• A Healthy Volunteer Study to Investigate the Relative Bioavailability of Two Forms of GSK598809 Capsules.
• A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy Smokers
• Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers
• Post-marketing Surveillance Study of Ex-intravenous Drug Abusers With Chronic Hepatitis C Treated With PegIntron Plus Rebetol (P04408/MK-4031-261)
• Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)
• Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)
• Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED)
• Study of the Abuse Liability of Oxycodone HCl/Niacin in Subjects With a History of Opioid Abuse
• Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED)
• Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
• Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse
• Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal
• Initialization of Methadone in Primary Care, Randomized Intervention Research for Preventing HCV Transmission Practices
• Quetiapine for the Reduction of Cocaine Use
• A Dose Ranging Study of Modafinil for Methamphetamine Dependence
• Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial
• A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine Reward
• A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)
• A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED)
• Drug Discrimination in Methadone-Maintained Humans Study 1
• First Episode Schizophrenia and Cannabis-Related Disorder Study
• Impact of Attention Deficit/Hyperactivity Disorder and Substance Use Disorder on Motorcycle Traffic Accidents
• Pilot Study Examining Effect for Dextroamphetamine to Treat Cocaine Dependence Plus Attention-deficit Hyperactivity Disorder (ADHD)
• To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334
• Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone
• Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors
• Aripiprazole Treatment for Methamphetamine Dependence Among High-risk Individuals
• Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation
• Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care
• Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
• "The Evaluation of Stimulant Withdrawal"
• Substance Abuse Pre-Treatment Screening Study
• A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809
• Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809
• Efficacy of D-Cycloserine for Enhancing the Effects of CBT for Substance Use
• Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
• HIV Risk Reduction and Drug Abuse Treatment in Iran
• Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
• HIV Risk Reduction and Drug Abuse Treatment in Malaysia
• Treatment of Polydrug-Using Opiate Dependents During Withdrawal
• Paroxetine Treatment in Outpatients With Comorbid PTSD and Substance Dependence
• Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSM
• Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder
• Effects of Fatty Acid Supplementation on Substance Dependent Individuals
• The Impact of Quetiapine on the Drug Abuse Patterns of Addicted Schizophrenic Patients
• Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD)
• Combined Treatment for Alcohol-Dependent Individuals With PTSD
• Prometa Pharmacotherapy for Methamphetamine Dependence
• Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
• Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories
• Quetiapine for Cocaine Use and Cravings
• Treatment of Comorbid Depression and Substance Abuse in Young People
• Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users
• Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance Abuse
• Effectiveness of ATMX in Treating Adolescents With ADHD and SUD
• Depakote ER Therapy for Mania Comorbid With Substance Abuse
• Abilify Therapy for Reducing Comorbid Substance Abuse
• Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia
• Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder
• Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users
• Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse Disorder
• Alcoholism and Schizophrenia: Effects of Clozapine
• Rivastigmine For Methamphetamine Dependent Individuals
• Prescription Opioid Effects in Abusers Versus Non-Abusers
• Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder
• Improving Hepatitis C Treatment in Injection Drug Users
• Effectiveness of Bupropion in Treating Marijuana Dependent Individuals
• Addition of Naltrexone to Methadone Taper
• Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder
• GHB Withdrawal Symptoms and Effectiveness of Treatment With Lorazepam Versus Pentobarbital - 1
• Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
• A Study of Cabergoline for the Treatment of Cocaine Dependence - 1
• Reserpine for the Treatment of Cocaine Dependence - 1
• Atomoxetine to Treat Adolescents With Coexisting Alcohol and Other Substance Use Disorder and ADHD
• Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1
• Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14
• Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11
• Prepulse Inhibition of Startle in Cocaine Dependence - 7
• Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Disorder - 5
• Nefazodone in the Treatment of Cocaine Dependence and Depression - 4
• Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1
• Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2
• Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1
• Behavioral Economics of Human Drug Self-Administration
• Multimodal Treatment Study of Children With Attention Deficit and Hyperactivity Disorder (MTA)
• Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7
• Buprenorphine Maintenance for Opiate Dependence - 6
• Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5
• Effects of Buprenorphine and Naloxone in Opiate Addicts - 4
• Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3
• Trial of Buprenorphine/Naloxone for Opiate Dependence - 2
• Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1
• Methamphetamine Abuse Treatment in Patients With AIDS - 1
• Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2
• Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1
• Early Phase II Trials for Cocaine Medication Development - 1
• Combining Behavioral Treatment With Agonist Maintenance - 1
• Dextroamphetamine as an Adjunct in Cocaine Treatment - 1
• Novel Medications for Opiate Detoxification - 4
• Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9
• A Laboratory Model for Heroin Abuse Medications - 8
• Early Phase II Trials for Cocaine Medication Development - 1
• New Approaches to Cocaine Abuse Medications (A) - 6
• Pergolide Treatment for Substance Abusers - 4
• Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16
• Effects of Combined Alcohol and Nitrous Oxide Intake - 15
• Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
• Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13
• Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12
• Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11
• Role of Instructions in Nitrous Oxide Effects and Choice - 10
• Effects of Alcohol History on Effects of Nitrous Oxide - 9
• Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8
• Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7
• Isoflurane at Subanesthetic Concentrations - 6
• Effects of Nitrous Oxide: A Dose-Response Analysis - 5
• Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4
• Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3
• Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2
• Effects of Subanesthetic Concentrations of Nitrous Oxide - 1
• Rapid Benzodiazepine Detoxification Using Flumazenil - 1
• Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1
• Carbamazepine Treatment of Cocaine Dependence - 1
• Flupenthixol Decanoate in Methamphetamine Smoking - 1
• Pharmacotherapy and Intensive Treatment - 2
• Pharmacotherapy and Intensive Treatment of Drug Abuse - 1
• Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1
• Treatment Efficacy for Drug Abuse and AIDS Prevention - 2
• Treatment Efficacy for Drug Abuse and AIDS Prevention - 1