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Clinical Trials for Sepsis

• The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis
• Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis
• Metformin and Lactoferrin in Sepsis in Icu
• Clinical Research on Shenfu Injection in Septic Patients
• Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial
• Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy
• Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation
• Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation
• Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients
• A Phase I Study of XJ101 in Chinese Healthy Subjects
• Safety and Feasibility of Metformin for Sepsis Induced AKI
• Continuous Spinal Anesthesia Versus General Anesthesia in Sepsis
• Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality
• Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis
• Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital
• Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
• Early Administration of Norepinephrine in Sepsis
• 8.4% Sodium Bicarbonate Locks in Intestinal Failure
• Alpha-Lipoic Acid in Patients With Sepsis
• The Impact of Early Norepinephrine Administration on Outcomes of Patients With Sepsis-induced Hypotension
• Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial
• Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis
• Neutrophil Elastase Inhibitor in Treatment of ARDS Patients With Mechanical Ventilation Caused by Sepsis
• Impact of Prophylactic Antibiotics on Bloodstream Infections After Liberation From Extracorporeal Membrane Oxygenation
• Alirocumab in Patients With Sepsis
• Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI)
• Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01)
• The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock
• Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome
• Hydrochloric Acid Lock Therapy in Children With Cancer
• Zinc Supplementation in Pediatric Sepsis
• Efficacy of Targeted Abdominal Perfusion Pressure in Septic Shock
• Effect of Montelukast Versus Co Enzyme in Sepsis
• A Phase 1, Randomized, Double-Blind, First-In-Human, Dose Escalation Study Investigating the Safety, Recovery, and Pharmacodynamics of Multiple Oral Administrations of SNIPR001 in Healthy Subjects
• Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
• GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS
• The Efficacy of YiQiFuMai Injection as an Adjunctive Treatment for Sepsis
• Outcome of High Dose Vitamin D on Prognosis of Sepsis Requiring Mechanical Ventilation
• Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa Bacteraemia
• Intravenously Administered M6229 in Critically Ill Sepsis Patients
• Clinical Efficacy of Megadose Vitamin C in Sepsis
• Early Vasopressors in Sepsis
• HAT for the Treatment of Sepsis Associated With NASTI
• Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis
• Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia
• Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus
• Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure
• Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients
• Epirubicin for the Treatment of Sepsis & Septic Shock
• Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa
• Personalized Immunotherapy in Sepsis
• Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis Complicated With Respiratory Failure
• Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury
• Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
• SY-005 （Recombinant Human Annexin A5）in Patients With Sepsis
• Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia
• Best Available Therapy With or Without Meropenem for Bloodstream Infections by Enterobacterales With High Level of Resistance to Carbapenems
• Safety Study of Inhaled Carbon Monoxide to Treat Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)
• Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection
• Effect of Vancomycin After Catheter Replacement
• Immunoinflammatory Regulation of Esketamine in Septic Patients
• Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria
• Efficacy and Safety of Kukoamine B Mesilate in Sepsis Patients
• High-dose Intravenous Vitamin C in Patients With Septic Shock
• The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis
• Efficacy and Safety of Colistin Based Antibiotic Therapy
• Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition
• Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
• Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact
• Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis
• A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients
• Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis
• Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
• The Effect of Esmolol on Patients With Sepsis
• Triple Therapy in Septic Shock Patients
• Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella Pneumoniae
• Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants
• Effects of Integrated Treatment of Traditional Medicine and Western Medicine for Sepsis-induced Cardiac Injury
• A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes
• Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Patients
• Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery
• Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis
• A Study of HY209 in Healthy Male Volunteers for Sepsis
• Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection
• Control of Fever in Septic Patients
• Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis
• Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
• Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
• Pentoxifylline Dose Optimization in Neonatal Sepsis
• Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients
• Adjuvant Use of Neostigmine in Sepsis and Septic Shock.
• Efficacy and Safety of Vitamin A Treatment for Children With Sepsis
• Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock
• Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis
• Safety and Efficacy of Oral Bovine Lactoferrin
• Rapid Atrial Fibrillation Treatment Strategy
• High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
• Adjunctive Sedation With Dexmedetomidine for the Prevention of Severe Inflammation and Septic Encephalopathy
• IgM-Enriched Immunoglobulin for Neonatal Sepsis
• Vitamin C, Vitamin B1 and Steroid in Sepsis
• Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course
• NICU Antibiotics and Outcomes Trial
• Efficacy of Cloxacillin and Fosfomycin Combination Versus Cloxacillin Monotherapy in Patients With MSSA Bacteremia
• Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock
• Azithromycin-Prevention in Labor Use Study (A-PLUS)
• RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI
• Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study)
• Inulin for Infections in the Intensive Care Unit
• Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis
• Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients
• GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study
• Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.
• Ascorbic Acid and Thiamine Effect in Septic Shock
• Comparison of Balanced Crystalloids and Normal Saline in Septic Patients
• t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection
• PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)
• Efficacy and Pharmacokinetics of Meropenem in Severe Septic Patients
• Treatment of Severe Infection With Antihyperlipidemia Drug
• Vitamin C & Thiamine in Sepsis
• The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy
• Vitamin C, Thiamine, and Steroids in Sepsis
• Pharmacokinetics of XueBiJing in Patients With Sepsis
• Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis
• Esomeprazole to Reduce Organ Failure in Sepsis
• Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis
• Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
• LIPIDS-P Trial Phase I/II
• Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury
• Efficacy of IgM Rich Immunoglobulin With Antibiotics for Bacterial Sepsis in Very Low Birth Weight Preterm Neonates
• Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants
• Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
• Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)
• Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System
• Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients
• Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study
• The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
• A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis
• Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis
• 7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis
• Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis
• The Effect of Fluid Resuscitation With 0.9% Sodium Chloride Versus Balanced Crystalloid Solution on Renal Function of Sepsis Patients
• The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis
• Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock
• Ethanol-lock Therapy for the Prevention of Non-tunneled Catheter-related Infection in Pediatric Patients
• Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
• The Efficacy of Xuebijing Injection on Sepsis
• Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients
• Tumescent Anesthesia Antibiotic Delivery (TAAD)
• Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death
• Adrenal Cortical Function and Vitamin A Deficiency in Sepsis
• Effect of Dexmedetomidine on Perfusion Index and Microcirculation in Severe Sepsis and Septic Shock Patients
• Midodrine Hydrochloride in Early Sepsis
• Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP)
• A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transp
• Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis
• Anticholium® Per Se
• Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia
• A Study of DEcolonization in Patients With HAematological Malignancies (DEHAM)
• Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis
• Dendritic Cells-Derived Exosomes in Human Sepsis
• Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis
• the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations
• Methylene Blue and Ozone in Early Sepsis
• Short-course Antimicrobial Therapy in Sepsis
• Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis
• Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis
• The Efficacy and Safety of Ta1 for Sepsis
• Effects of Dexmedetomidine on Respiratory Function and Inflammatory Responses in Patient With Sepsis Undergoing Cleaning Focus of Infection
• Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
• Immune Reconstitution of Immunosuppressed Sepsis Patients
• The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis
• Neonatal Vancomycin Trial
• The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis
• Midodrine During Recovery From Septic Shock
• Pharmacokinetics, Safety, Tolerability and Pharmacodynamics of BMS-986189 in Healthy Subjects
• High Dose Intravenous Ascorbic Acid in Severe Sepsis
• Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock
• Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
• The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia
• Vitamin D Status in Patients With Severe Sepsis
• Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic Shock
• L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury
• Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients.
• Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
• Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
• Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China
• A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients
• Preliminary Research On Two-step Dosing Of Imipenem/Cilastatin
• Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis
• Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults
• Severe Sepsis in Children - IMPRESS-C
• Volume Therapy With Crystalloids and Colloids and Hemodynamic Monitoring in Patients With Severe Sepsis
• Heparin Versus Taurolidine to Bloodstream Infection Prevention Related in Central Venous Catheter in Children
• Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis
• Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock
• Project 4B: Lower Extremity Strength Training in ICU Patients
• Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients
• Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin
• A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects
• Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response
• Safety, Tolerability and Efficacy of Ceftaroline in Paediatrics With Late-Onset Sepsis
• Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci
• Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics
• Trial of Hyperoxic O2 Therapy vs. Normoxic O2 Therapy in Sepsis
• Project 4A: Inspiratory Muscle Training and Diaphragm Strength
• Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department
• GM-CSF to Decrease ICU Acquired Infections
• Balanced Salt Solution VS. Normal Saline Solution in Septic Shock
• Dose Assessment of Melatonin in Sepsis Trial
• Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS
• A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis
• Antihypertensive Medications and the Risk of Sepsis
• Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition
• Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units
• Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure
• Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock
• Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis
• RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp.
• Pentoxifylline and Late Onset Sepsis in Preterm Infants
• Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis
• Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status
• The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis
• Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury
• Preemptive Ethanol Lock Therapy in Pediatric Bloodstream Infection
• rhTPO in Critical Patients With Thrombocytopenia
• Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care
• Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects
• Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis
• Efficacy of Mw Vaccine in Treatment of Severe Sepsis
• Angiotensin II Antagonist in Severe Sepsis
• Prehospital Antibiotics Against Sepsis Trial
• A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)
• Ubiquinol (Reduced COQ10) for Patients With Sepsis
• Early Use of Norepinephrine in Septic Shock Resuscitation
• Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections
• Umbilical Cord Care for the Prevention of Colonization
• The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis
• Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin
• Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock
• Methylene Blue in Severe Sepsis and Septic Shock
• ASpirin for Patients With SEPsis and SeptIc Shock
• Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial
• The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
• Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis
• Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio)
• Melatonin in Healthy Volunteers
• Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth
• Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis
• Single Dose Enteral Tranexamic Acid in Critically Ill Patients
• The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis
• Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term
• Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy
• Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli
• Outcome Following Vitamin C Administration in Sepsis
• Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants
• Pharmacology of Exenatide in Pediatric Sepsis
• A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis
• Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis
• Antimicrobial Catheter Lock Solution for the Treatment of Central Line Associated Bloodstream Infection (CLABSI)
• Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis
• Citrulline in Severe Sepsis
• Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection
• Preemptive Resuscitation for Eradication of Septic Shock
• Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome
• Ascorbic Acid (Vitamin C) Infusion in Human Sepsis
• Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
• Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.
• Evaluation of the Clinical Practice of Using of a 70% Ethanol Lock Solution for the Prevention of Catheter Related Blood Stream Infections in Pediatric Patients Undergoing Intestinal Rehabilitation
• The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia
• Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates
• Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock
• Lactated Ringer Versus Albumin in Early Sepsis Therapy
• Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis
• The Effect of Ketanserin on the Microcirculation in Sepsis
• Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients
• GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock
• Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS)
• Role of Antibiotics in Preventing Infection in Babies Born Through Meconium Stained Liquor
• Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
• Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture
• The Effect of Moderate-Dose Steroid Therapy in Sepsis
• Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis
• Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension
• Effect of L-arginine and Glutamine on Preterm
• Infant Severe Sepsis and Bacterial Meningitis in Malawi
• Hyperinsulinemic Therapy in Sepsis
• Safety of Heparin in Patients With Septic Shock
• Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants
• Clarithromycin as Immunomodulator for the Management of Sepsis
• Metronidazole Pharmacokinetics (PK) in Premature Infants
• Biological Modulation of Bacterial QSSMs, Innate and Adaptive Immunity by Antibiotics, Probiotics and Prebiotics in Healthy Individuals
• Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection
• Paracetamol Toxicity in Septic Patients
• Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant
• A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock
• A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock
• Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
• Immunomodulatory Properties of Ketamine in Sepsis
• Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients
• Simplified Antibiotic Therapy for Sepsis in Young Infants
• Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'
• Terlipressin in Septic Shock: Effects on Microcirculation
• Topical Antibiotics for Prevention of Intensive Care Unit (ICU) Central Line Infections
• Statins for Acutely Injured Lungs From Sepsis
• Scandinavian Starch for Severe Sepsis/Septic Shock Trial
• A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo)
• The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia
• Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome
• Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates
• The Influence of Oral Hygiene on Local Wound and Systemic Infection in Patients With Percutaneous Endoscopic Gastrostomy Placement
• Simplified Antibiotic Regimens for Outpatient Treatment of Suspected Sepsis in Neonates and Young Infants in Bangladesh
• Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis
• Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis
• Rapid Administration of Insulin in Sepsis
• Fluid Resuscitation in Early Septic Shock
• Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis
• Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology
• Septic Encephalopathy and Late Cognitive Dysfunction
• Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study
• Angiotensin in Septic Kidney Injury Trial
• Efficacy of Thymosin alpha1 for Severe Sepsis
• Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis Patients
• Ethanol Locks for the Treatment of Central Venous Line Infections
• Statin Therapy in the Treatment of Sepsis
• Hydrocortisone for Prevention of Septic Shock
• Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis
• Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis
• Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure
• Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis
• A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis
• AZD9773 Dose Escalation Study
• Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen
• Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
• Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock
• An Open Label Study of Severe Sepsis in Adults
• The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death
• A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult
• Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia
• Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
• Statins for the Early Treatment of Sepsis
• A Study in Sepsis Patients With Renal Failure
• Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe Sepsis
• The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis
• Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
• Methylene Blue in Sepsis: A Randomized Controlled Trial
• Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis
• Catheter Related - Gram Positive Bloodstream Infections
• Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
• Statin for Immunomudulation in Sepsis
• Pharmacokinetic of Ceftriaxone in Septic ICU Patients
• The Effect of Etomidate on Patient Outcomes After Single Bolus Doses
• Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
• Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections
• To Evaluate the Treatment Effect of an Anti-Infective Agent for Complicated Infections (0826-053)
• Cortisol Control of Human Inflammatory Responses to Endotoxin
• The CRISIS Prevention Study
• Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)
• Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
• Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers
• Effect of Rosuvastatin in Abdominal Sepsis
• The Effects of HIV Protease Inhibitors in Severe Sepsis
• Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women
• ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis
• Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.
• Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
• Intravenous Clarithromycin in Septic Syndrome
• Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh?
• BaSES Trial: Basel Starch Evaluation in Sepsis
• Selenium, as Sodium Selenite, in the Treatment of Septic Shock
• Treatment Targets for Chronic Hypertension in Pregnancy
• Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
• Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
• Vancomycin Study: Treatment of Catheter Related Bloodstream Infection Caused by Coagulase Negative Staphylococcus
• Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome
• A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers
• Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock
• Efficacy & Safety of Resatorvid in Adults With Severe Sepsis
• The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients
• Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation
• Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
• Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
• Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections
• Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
• Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections
• Unfractioned Heparin for Treatment of Sepsis
• GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults
• A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation
• Safety and Efficacy of Dalbavancin Versus Vancomycin in the Treatment of Catheter-Related Bloodstream Infections
• A Trial of Heparin in Patients With Severe Sepsis Who Are Undergoing Treatment With Drotrecogin Alfa (Activated)
• Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
• A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis
• The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients With Severe Sepsis
• A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis
• Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
• A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis
• Pleconaril Enteroviral Sepsis Syndrome
• Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis